Characterization of MORN2 stability and regulatory function in LC3-associated phagocytosis in macrophages

Autor: Maya Morita, Mayu Kajiye, Chiye Sakurai, Shuichi Kubo, Miki Takahashi, Daiki Kinoshita, Naohiro Hori, Kiyotaka Hatsuzawa

Publikováno v: Biology Open, Vol 9, Iss 6 (2020)

Microtubule-associated protein A1/B1-light chain 3 (LC3)-associated phagocytosis (LAP) is a type of non-canonical autophagy that regulates phagosome maturation in macrophages. However, the role and regulatory mechanism of LAP remain largely unknown.

Externí odkaz: https://doaj.org/article/d96c3ffd45c3457c97aafb702385e788

Syntaxin 11 regulates the stimulus-dependent transport of Toll-like receptor 4 to the plasma membrane by cooperating with SNAP-23 in macrophages

Autor: Chiye Sakurai, Daiki Kinoshita, Maya Morita, Masashi Tsunematsu, Naohiro Hori, Kiyotaka Hatsuzawa

Publikováno v: Molecular Biology of the Cell
Kinoshita, Daiki, Sakurai Chiye, Morita Maya et al. Syntaxin 11 regulates the stimulus-dependent transport of Toll-like receptor 4 to the plasma membrane by cooperating with SNAP-23 in macrophages. Molecular biology of the cell, 2019, 30(9), 1085-1097.

Syntaxin 11 (stx11) is a soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) that is selectively expressed in immune cells; however, its precise role in macrophages is unclear. We showed that stx11 knockdown reduces the ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8830c9af315e865b68c77f500a6ff0ea
http://repository.lib.tottori-u.ac.jp/12857

Quantitative analysis of phagosome formation and maturation using an Escherichia coli probe expressing a tandem fluorescent protein

Autor: Naohiro Hori, Kiyotaka Hatsuzawa, Chiye Sakurai, Daiki Kinoshita, Kazumasa Sawaki, Maya Morita

Publikováno v: Morita Maya, Sawaki Kazumasa, Kinoshita Daiki, et al. Quantitative analysis of phagosome formation and maturation using an Escherichia coli probe expressing a tandem fluorescent protein. JOURNAL OF BIOCHEMISTRY. 2017. 162(5). 309-316. doi:10.1093/jb/mvx03

Phagosome formation and maturation are essential innate immune mechanisms to engulf and digest foreign particles. To analyze these processes quantitatively, we established a specific Escherichia coli probe expressing a tandem fluorescent protein, com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bfc19c83f066ca2168b264bb48c6d5
http://id.nii.ac.jp/1824/00007236/

Oct motif variants in Beckwith-Wiedemann syndrome patients disrupt maintenance of the hypomethylated state of the H19/IGF2 imprinting control region

Autor: Chihiro Murata, Naohiro Hori, Shuichi Kubo, Hanayo Okamura, Kiyotaka Hatsuzawa, Chiye Sakurai, Taku Sakasegawa

Publikováno v: FEBS lettersReferences. 594(10)

The methylation status of imprinting control center 1 (IC1) regulates the monoallelic transcription of H19 and Igf2 in mammalian cells. Several single nucleotide variants in Oct motifs within IC1 occur in patients with Beckwith-Wiedemann syndrome (BW

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32441378934b8b68240979191add3686
https://pubmed.ncbi.nlm.nih.gov/32012256

OCT3/4-binding sequence-dependent maintenance of the unmethylated state of CTCF-binding sequences with DNA demethylation and suppression of de novo DNA methylation in the H19 imprinted control region

Autor: Shuichi Kubo, Kiyotaka Hatsuzawa, Taku Sakasegawa, Chiye Sakurai, Naohiro Hori

Publikováno v: Gene. 743:144606

DNA demethylation and suppression of de novo DNA methylation are activities that maintain an unmethylated state. However, the strength of these two activities at the same locus has not been estimated separately. Furthermore, the association between t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5b741e9bef0d475d6bc6b5696e7604
https://doi.org/10.1016/j.gene.2020.144606