Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Naohiro, Yamaguchi"'
Autor:
Noriyuki Nishida, Naohiro Yamaguchi, Takujiro Homma, Daisuke Ishibashi, Hiroya Tange, Takayuki Fuse, Takehiro Nakagaki, Ryuichiro Atarashi
Publikováno v:
Neuroscience Research. 171:34-40
The defining characteristic of prion diseases is conversion of a cellular prion protein (PrPC) to an abnormal prion protein (PrPSc). The exogenous attachment of PrPSc to the surface of a target cell is critical for infection. However, the initial int
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2573
Human-induced pluripotent stem cells (hiPSCs) provide a powerful platform to study biophysical and molecular mechanisms underlying the pathophysiology of genetic mutations associated with cardiac arrhythmia. Human iPSCs can be generated by reprogrami
Autor:
Naohiro Yamaguchi, Norio Abiru, Osamu Higuchi, Haruki Koike, Masahisa Katsuno, Tomonori Tanaka, Hiroaki Kawano, Akira Tsujino, Hidenori Matsuo, Akihiro Mukaino, Fumiaki Tanaka, Makoto Oishi, Misako Kunii, Asami Saito, Yasuhiro Maeda, Eiko Tsuiki, Shunya Nakane, Yukimasa Arita
Publikováno v:
Journal of Neurology
Objective To determine whether autonomic dysfunction in neurosarcoidosis is associated with anti-ganglionic acetylcholine receptor (gAChR) antibodies, which are detected in autoimmune autonomic ganglionopathy. Methods We retrospectively extracted cas
Autor:
Naohiro Yamaguchi
Publikováno v:
Journal of General Physiology. 154
It is controversial whether the cardiac type-2 ryanodine receptor harboring a catecholaminergic polymorphic ventricular tachycardia-associated point mutation is regulated by luminal or cytosolic Ca2+. This commentary discusses new findings supporting
Publikováno v:
Biophysical Journal. 122:234a
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627068
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6af8c5492197ff61174a8aff8343d55c
https://doi.org/10.1007/978-1-0716-2707-5_4
https://doi.org/10.1007/978-1-0716-2707-5_4
Autor:
Venkat R. Chirasani, Hannah G. Addis, Naohiro Yamaguchi, Gerhard Meissner, Daniel A. Pasek, Le Xu, Nikolay V. Dokholyan
Publikováno v:
American Journal of Physiology-Cell Physiology. 317:C358-C365
Cryoelectron microscopy and mutational analyses have shown that type 1 ryanodine receptor (RyR1) amino acid residues RyR1-E3893, -E3967, and -T5001 are critical for Ca2+-mediated activation of skeletal muscle Ca2+ release channel. De novo missense mu
Autor:
Tatsuya Kishino, Yoshihiro Komohara, Koh-ichiro Yoshiura, Naohiro Yamaguchi, Chisei Satoh, Miako Sakaguchi, Hiroyuki Mishima, Akira Imamura, Hiroki Ozawa, Masahiro Nakashima, Naohiro Kurotaki, Shintaro Yoshida, Takeshi Tanaka, Akira Kinoshita, Shinji Ono, Katsuya Matsuda, Yoshiro Morimoto
Publikováno v:
Neurology. 92:e2364-e2374
OBJECTIVE: To identify genes related to normal-pressure hydrocephalus (NPH) in one Japanese family with several members with NPH. METHODS:We performed whole-exome sequencing (WES) on a Japanese family with multiple individuals with NPH and identified
Autor:
Asima Chakraborty, Daniel A Pasek, Tai-Qin Huang, Angela C Gomez, Naohiro Yamaguchi, Mark E Anderson, Gerhard Meissner
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104338 (2014)
In cardiac muscle, the release of calcium ions from the sarcoplasmic reticulum through ryanodine receptor ion channels (RyR2s) leads to muscle contraction. RyR2 is negatively regulated by calmodulin (CaM) and by phosphorylation of Ca2+/CaM-dependent
Externí odkaz:
https://doaj.org/article/2c7ef560bb6e49e5aa3ee8fb6c33ffea
Autor:
Gerhard Meissner, Jordan S. Carter, Venkat R. Chirasani, Nikolay V. Dokholyan, Naohiro Yamaguchi, Le Xu, Daniel A. Pasek
Publikováno v:
Journal of Biological Chemistry. 293:19501-19509
Cryo-electron micrograph studies recently have identified a Ca2+-binding site in the 2,200-kDa ryanodine receptor ion channel (RyR1) in skeletal muscle. To clarify the role of this site in regulating RyR1 activity, here we applied mutational, electro