Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Naohiko Takahata"'
Autor:
Nakano, Norihito, Hatakeyama, Yoshihisa, Fukatsu, Ryo, hayashi, Shuichiro, Fujii, Mitsuru, Fujimori, Kenji, Naohiko, Takahata
Publikováno v:
In Progress in Neuropsychopharmacology & Biological Psychiatry 1999 23(6):1053-1062
Autor:
Taku Yoshida, Kayo Tsuzuki, Nobuhiro Fujii, Yuji Takamaru, Naohiko Takahata, Yorihide Hayashi, Ryo Fukatsu, Kunihiko Kobayashi
Publikováno v:
International Journal of Experimental Pathology. 78:1-8
Pathological and immunopathological studies were carried out on snake coiled fibres (SCF) which occurred in affected soleus muscle in chloroquine treated rats. The SCF began to appear in denervated soleus muscle by 8 days after chloroquine injection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced9939b1d93952f2df56333aeecabe3
https://doi.org/10.1046/j.1365-2613.1997.9950333.x
https://doi.org/10.1046/j.1365-2613.1997.9950333.x
Autor:
Shinichi Hatta, Naohiko Takahata, Hiroki Ozawa, Toshikazu Saito, Masayuki Watanabe, Sadamu Toki, Hiroki Kamada
Publikováno v:
Cellular and Molecular Neurobiology. 19:109-117
1. Antidepressants have been used clinically for many years; however, the neurochemical mechanism for their therapeutic effect has not been clarified yet. Recent reports indicate that chronic antidepressant treatment directly affects the postsynaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d20f58950c2496ccc8b47cc14360a31e
https://doi.org/10.1023/a:1006972709733
https://doi.org/10.1023/a:1006972709733
Recent progress in brain science has been remarkable, especially with regard to advances in the area of neuroscience. Particularly in the past decade, there have been many important discoveries about signal transduction in the brain. With this backgr
Autor:
Shin Shichinohe, E. Hashimoto, Peter Riederer, Naohiko Takahata, Carola Lang, Hiroki Ozawa, Toshikazu Saito
Publikováno v:
Alcoholism: Clinical and Experimental Research. 22:84S-87S
In animal and culture cell experiments, the upregulation of cAMP-related signal transduction after chronic opioid administration has been hypothesized to be an adaptive change of the molecular mechanism to maintain homeostasis in intracellular signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b1d257f66707cebec40046b16c5058
https://doi.org/10.1111/acer.1998.22.s3_part1.84s
https://doi.org/10.1111/acer.1998.22.s3_part1.84s
Autor:
Lutz Frölich, Naohiko Takahata, Jobst Böning, E. Hashimoto, Peter Riederer, K Maurer, Toshikazu Saito, Hiroki Ozawa
Publikováno v:
Alcoholism: Clinical and Experimental Research. 22:88S-92S
Reduced adenylyl cyclase activity after chronic ethanol exposure has been reported. In this study, we investigated by immunoblotting whether quantitative changes of adenylyl cyclase isoforms (type I, type II, and type V/VI adenylyl cyclases) exist in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fb4ccaff6af155ae9f8abbefd16cd9
https://doi.org/10.1111/acer.1998.22.s3_part1.88s
https://doi.org/10.1111/acer.1998.22.s3_part1.88s
Autor:
Hiroki Ozawa, Peter Riederer, Toshikazu Saito, Naohiko Takahata, Yuji Odagaki, Tsukasa Koyama, Nobuyuki Nishi
Publikováno v:
Brain Research. 789:84-91
Guanine nucleotide-binding regulatory proteins (G proteins) play a pivotal role in receptor-mediated transmembrane signal transduction, and have been implicated in modes of action of psychotropic drugs as well as in pathogenesis of psychiatric disord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d621579273028ffb9db71019039d67a
https://doi.org/10.1016/s0006-8993(98)00019-5
https://doi.org/10.1016/s0006-8993(98)00019-5
Autor:
Yorihide Hayashi, Nobuyuki Sasaki, Nobuhiro Fujii, Ryo Fukatsu, Koichi Kimura, Taku Yoshida, Kayo Tsuzuki, Haruyasu Yamaguchi, Naohiko Takahata, Peter St George-Hyslop
Publikováno v:
Brain Research. 789:307-314
Presenilin-1 (PS-1) has been identified as the protein encoded by the chromosome 14 locus that, when mutated, leads to familial Alzheimer's disease (FAD). The role PS-1 plays in the pathogenesis of Alzheimer's disease (AD) remains unclear. Using a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a18af6e1589500f942c813b41b6fb92
https://doi.org/10.1016/s0006-8993(98)00027-4
https://doi.org/10.1016/s0006-8993(98)00027-4
Autor:
Hitoshi Chiba, Yuji Aizawa, Nobuhiro Fujii, Naohiko Takahata, Kunihiko Kobayashi, Ryo Fukatsu, Yuji Takamaru, Kayo Tsuzuki
Publikováno v:
Brain Research. 768:208-214
Amyloid deposits in Alzheimer's disease (AD) are composed of amyloid beta protein (A beta) and many other components called amyloid-associated proteins. Apolipoprotein E (apoE) is one of the most important amyloid-associated proteins. The role apoE p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519849e52221767cafb1e69be26111d4
https://doi.org/10.1016/s0006-8993(97)00640-9
https://doi.org/10.1016/s0006-8993(97)00640-9
Autor:
Yuji Aizawa, Naohiko Takahata, Nobuhiro Fujii, Nobuyuki Sasaki, Kayo Tsuzuki, Yuji Takamaru, Yorihide Hayashi, Ryo Fukatsu, Taku Yoshida
Publikováno v:
Brain Research. 764:283-288
To understand the retinal changes in Alzheimer disease (AD) patients, pathological and immunocytochemical studies were performed on retinal cells in the chloroquine-treated rats at 0, 4, 8, 12, 16, 20, and 24 weeks after the initial injection, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0e6e7ab51a4edc3a2a216f547d7a2c
https://doi.org/10.1016/s0006-8993(97)00600-8
https://doi.org/10.1016/s0006-8993(97)00600-8