Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Naohiko Ohkubo"'
Autor:
Yasukiyo Mori, Satoshi Murasawa, Mitsuo Inada, Toshiji Iwasaka, Katsuya Maruyama, Hiroaki Matsubara, Naohiko Ohkubo, Kazuhisa Kijima, Yoshio Yazaki, Issei Komuro
Publikováno v:
Circulation Research. 79:887-897
Mechanical stress plays a pivotal role in the development of cardiac hypertrophy during hemodynamic overload, and angiotensin (Ang) II secreted from stretched myocytes plays an important role in mechanical stretch–induced hypertrophy. In the presen
Autor:
Yasukiyo Mori, Naohiko Ohkubo, Hiroaki Matsubara, Katsuya Maruyama, Kazuhisa Kijima, Mitsuo Inada, Satoshi Murasawa
Publikováno v:
Hypertension. 27:529-534
Abstract In the present study, rat angiotensin II type 2 (AT 2 ) receptor expression was upregulated in confluence-arrested PC12 cells compared with expression in proliferating cells. Treatment with cycloheximide inhibited the increase in mRNA levels
Autor:
Satoshi Murasawa, Naohiko Ohkubo, Toshiji Iwasaka, Katsuya Maruyama, Mitsuo Inada, Hiroaki Matsubara, Yasukiyo Mori, Kazuhisa Kijima
Publikováno v:
Hypertension Research. 19:271-279
The rat angiotensin II type 2 receptor (AT2-R) gene was isolated, and cis-regulatory regions in its 5"- flanking area were analyzed. Primer extension and RNase protection analyses revealed a single transcriptional initiation site at the position 24bp
Autor:
Tetsuro Sugiura, Mitsuo Inada, Toshiji Iwasaka, Hisako Tsuji, Naohiko Ohkubo, Seishi Nakamura
Publikováno v:
Chest. 103:1320-1324
To investigate the serial changes of the infarcted and the noninfarcted areas, first-pass radionuclide angiocardiography was performed in 16 patients with uncomplicated anterior myocardial infarction (MI) at four weeks, one year, and two years after
Autor:
Hisato Nakamori, Mitsuo Inada, Yuka Wakayama, Toshiji Iwasaka, Naohiko Ohkubo, Hitoshi Koito, Tsutomu Katoh, Junichi Suzuki
Publikováno v:
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 30:990-996
A 85-year-old woman consulted our hospital with general fatigue, palpitation and chest discomfort changing with different postures. Her electrocardiogram showed sinus tachycardia, atrial premature beats and left atrial overload. 53% cardiothoracic ra
Autor:
Toshiji Iwasaka, Naohiko Ohkubo, Yasutaka Moriguchi, Satoshi Murasawa, Yoshiaki Tsutsumi, Hiroya Masaki, Yasunobu Shibasaki, Yoshihisa Nozawa, Hiroaki Matsubara, Yasukiyo Mori, Hiroshi Kamihata, Mitsuo Inada, Katsuya Maruyama, Kazuhisa Kijima
Publikováno v:
Circulation research. 83(10)
Abstract —The expression pattern of angiotensin (Ang) II type 2 receptor (AT 2 -R) in the remodeling process of human left ventricles (LVs) remains poorly defined. We analyzed its expression at protein, mRNA, and cellular levels using autopsy, biop
Autor:
Yoshiaki Tsutumi, Yoshinobu Shibazaki, Mitsuo Inada, Hiroaki Matsubara, Naohiko Ohkubo, Yasukiyo Mori, Satoshi Murasawa, Katsuya Maruyama, Toshiji Iwasaka, Hiroya Masaki, Kazuhisa Kijima, Yoshihisa Nozawa
Publikováno v:
Circulation. 96(11)
Background Angiotensin (Ang) II type 1 receptor (AT 1 -R) induces cardiomyocyte hypertrophy and fibroblast proliferation, whereas the physiological role of AT 2 -R in cardiac remodeling remains poorly defined. Methods and Results Using Bio14.6 cardio
Publikováno v:
Chest. 106(3)
Prolonged survival of the patient with a single ventricle is rare. We report the case of a 57-year-old man who has type A3 of Van Praagh's classification of single ventricle with pulmonary hypertension without pulmonary stenosis. Favorable streaming,