Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Naofumi Yui"'
Autor:
Fumiaki Ando, Shuichi Mori, Naofumi Yui, Tetsuji Morimoto, Naohiro Nomura, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Yoshiaki Kondo, Hiroyuki Kagechika, Shinichi Uchida
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Patients suffering from congenital nephrogenic diabetes insipidus (NDI) fail to concentrate urine due to mutations in vasopressin type 2 receptor (V2R). Here Ando et al. show that agents disrupting the interaction between PKA and AKAPs restore aquapo
Externí odkaz:
https://doaj.org/article/8c60b14a92e94b27bd57f69fed3d984d
Autor:
Fumiaki Ando, Eisei Sohara, Tetsuji Morimoto, Naofumi Yui, Naohiro Nomura, Eriko Kikuchi, Daiei Takahashi, Takayasu Mori, Alain Vandewalle, Tatemitsu Rai, Sei Sasaki, Yoshiaki Kondo, Shinichi Uchida
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The water channel AQP2 mediates the concentration of urine in the kidney. Here Ando et al. show that Wnt5 promotes collecting duct permeability by regulating AQP2 expression and localization through activation of the calmodulin/calcineurin signalling
Externí odkaz:
https://doaj.org/article/29e7b2aadd534db090339dd9c18e6a53
Publikováno v:
Cells, Vol 9, Iss 4, p 1057 (2020)
We previously showed that in polarized Madin–Darby canine kidney (MDCK) cells, aquaporin-2 (AQP2) is continuously targeted to the basolateral plasma membrane from which it is rapidly retrieved by clathrin-mediated endocytosis. It then undertakes mi
Externí odkaz:
https://doaj.org/article/21c88428a7cb48b286ba0485d5aa644b
Publikováno v:
Biology Open, Vol 1, Iss 2, Pp 101-108 (2012)
Summary Remodeling of the actin cytoskeleton is required for vasopressin (VP)-induced aquaporin 2 (AQP2) trafficking. Here, we asked whether VP and forskolin (FK)-mediated F-actin depolymerization depends on AQP2 expression. Using various MDCK and LL
Externí odkaz:
https://doaj.org/article/27629c680967407ebadcc28a89f0d477
Autor:
Yu Hara, Fumiaki Ando, Daisuke Oikawa, Koichiro Ichimura, Hideki Yanagawa, Yuriko Sakamaki, Azuma Nanamatsu, Tamami Fujiki, Shuichi Mori, Soichiro Suzuki, Naofumi Yui, Shintaro Mandai, Koichiro Susa, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Mikiko Takahashi, Sei Sasaki, Hiroyuki Kagechika, Fuminori Tokunaga, Shinichi Uchida
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Protein kinase A (PKA) directly phosphorylates aquaporin-2 (AQP2) water channels in renal collecting ducts to reabsorb water from urine for the maintenance of systemic water homeostasis. More than 50 functionally distinct PKA-anchoring proteins (AKAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2950337696c57ce850895fedc0dfd68e
https://doi.org/10.1073/pnas.2202125119
https://doi.org/10.1073/pnas.2202125119
Publikováno v:
Biochemical and Biophysical Research Communications. 490:1039-1044
Vasopressin catalyzes aquaporin-2 phosphorylation at several serine sites in the C-terminal region. Compared with Ser-256 and Ser-269 phosphorylation, the role of Ser-261 phospho-regulation on vasopressin-regulated AQP2 apical translocation is largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65fc510fc4cde16913bd4cb23903e496
https://doi.org/10.1016/j.bbrc.2017.06.162
https://doi.org/10.1016/j.bbrc.2017.06.162
Publikováno v:
Biochemical and Biophysical Research Communications. 482:524-529
Aquaporin-2 (AQP2) is a water channel in collecting duct principal cells in the kidney. Vasopressin catalyzes AQP2 phosphorylation at several serine sites in its C-terminus: Ser-256, Ser-261, and Ser-269. Upon stimulation by vasopressin, Ser-269 phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c948dcde7db92e1b31cfcc0e7c33f941
https://doi.org/10.1016/j.bbrc.2016.11.118
https://doi.org/10.1016/j.bbrc.2016.11.118
Autor:
Shinichi Uchida, Fumiaki Ando, Tatemitsu Rai, Naofumi Yui, Tetsuji Morimoto, Hiroyuki Kagechika, Eisei Sohara, Yoshiaki Kondo, Naohiro Nomura, Shuichi Mori, Sei Sasaki
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Congenital nephrogenic diabetes insipidus (NDI) is characterized by the inability of the kidney to concentrate urine. Congenital NDI is mainly caused by loss-of-function mutations in the vasopressin type 2 receptor (V2R), leading to impaired aquapori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acae80befd3bdede8bec8006cb91759
https://doi.org/10.1038/s41467-018-03771-2
https://doi.org/10.1038/s41467-018-03771-2
Autor:
Yumi Noda, Soichiro Iimori, Hidenori Nishida, Naofumi Yui, Tomokazu Okado, Sei Sasaki, Shinichi Uchida, Hiromi Kihira, Tatemitsu Rai, Shotaro Naito
Publikováno v:
Nephrology. 20:601-608
Aim To investigate the association between iron deficiency anaemia and mortality risk and assess the changes in anaemia and iron status after primary management by a nephrologist. Methods In this prospective cohort study, we stratified 951 non-dialys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aacb1293ccc6a6f5c55eac8964cbc26
https://doi.org/10.1111/nep.12493
https://doi.org/10.1111/nep.12493
Autor:
Yuki Yoshizaki, Naofumi Yui, Junichi Ishigami, Shinichi Uchida, Tatemitsu Rai, Tomokazu Okado, Soichiro Iimori, Katusyuki Oi, Eisei Sohara, Sei Sasaki
Publikováno v:
General Medicine. 16:103-106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::322faf730e0b260fbfde5f239dc2316b
https://doi.org/10.14442/general.16.103
https://doi.org/10.14442/general.16.103