Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Naofumi Seira"'
Autor:
Masato Mashimo, Asuka Shimizu, Aimi Mori, Ayaka Hamaguchi, Keijo Fukushima, Naofumi Seira, Takeshi Fujii, Hiromichi Fujino
Publikováno v:
Biochemical and Biophysical Research Communications. 623:133-139
E type prostanoid 4 (EP4) receptors and their signaling pathways have been implicated in the development and malignant transformation of colorectal cancer. We herein demonstrated that the mono(ADP-ribosyl)ation of histone deacetylase (HDAC)1 and HDAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec41cc08f1f74a080e1ab9740042d178
https://doi.org/10.1016/j.bbrc.2022.07.055
https://doi.org/10.1016/j.bbrc.2022.07.055
Autor:
Akito Onishi, Akiko Higashiyama, Shunya Yanagawa, Naofumi Seira, John W Regan, Kento Ohkawachi, Masaya Denda, Keijo Fukushima, Akira Otaka, Hiromichi Fujino
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1cf61865e605d6e4c2a232df26846ab
https://doi.org/10.1254/jpssuppl.95.0_1-p-092
https://doi.org/10.1254/jpssuppl.95.0_1-p-092
Autor:
Makiko Wasai, John W. Regan, Yutaka Tamura, Naofumi Seira, Akiko Suganami, Takayoshi Arai, Hiromichi Fujino, Naoki Yanagisawa, Keijo Fukushima, Takuya Honda, Toshihiko Murayama, Naoto Yamaguchi
Publikováno v:
Biologicalpharmaceutical bulletin. 40(10)
Ministry of Education, Culture, Sports, Science and Technology of Japan [JP17K08308]; Center of Excellence (COE) program from Chiba University of Japan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b170f9d39330fc6bb73d2cd3ac3abb6
https://pubmed.ncbi.nlm.nih.gov/28966256
https://pubmed.ncbi.nlm.nih.gov/28966256
Autor:
Hiromichi Fujino, W John Regan, Keijo Fukushima, Masato Mashimo, Naoki Yanagisawa, Toshihiko Murayama, Kazuyuki Yamagata, Naoki Kurata, Yumi Araki, Hiroyuki Nakamura, Naofumi Seira
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fd48e0045e7e08cbcbe95580b5a4739
https://doi.org/10.1254/jpssuppl.92.0_2-p-125
https://doi.org/10.1254/jpssuppl.92.0_2-p-125
Autor:
Naoki Kurata, Yumi Araki, Keijo Fukushima, Hiromichi Fujino, Toshihiko Murayama, Naofumi Seira, Kazuyuki Yamagata, Masato Mashimo, Hiroyuki Nakamura, John W. Regan, Naoki Yanagisawa
Publikováno v:
Pharmacology Research & Perspectives
The up‐regulated expression of E‐type prostanoid (EP) 4 receptors has been implicated in carcinogenesis; however, the expression of EP4 receptors has also been reported to be weaker in tumor tissues than in normal tissues. Indeed, EP4 receptors h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8d99331d4730a4ab12fcadb0036eed
http://repo.lib.tokushima-u.ac.jp/115684
http://repo.lib.tokushima-u.ac.jp/115684
Autor:
Naoki Kurata, Yumi Araki, Hiromichi Fujino, Naofumi Seira, Toshihiko Murayama, John W. Regan, Hiroyuki Nakamura
Publikováno v:
European journal of pharmacology. 768
Approximately two decades have passed since E-type prostanoid 4 (EP4) receptors were cloned, and the signaling pathways mediated by these receptors have since been implicated in cancer development through the alliance of Gαi-protein/phosphatidylinos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2dfe3ec3e3213d7a7ffbe0ca606427
https://pubmed.ncbi.nlm.nih.gov/26518053
https://pubmed.ncbi.nlm.nih.gov/26518053
Autor:
Kenji Yoshida, Sho Otake, John W. Regan, Naofumi Seira, Hiromichi Fujino, Christopher M. Sanchez, Toshihiko Murayama
Publikováno v:
Pharmacology Research & Perspectives
Increases in prostaglandin E2 (PGE2) and cyclooxygenase-2 (COX-2) levels are features of colon cancer. Among the different E-type prostanoid receptor subtypes, EP4 receptors are considered to play a crucial role in carcinogenesis by, for example, ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6facbce4ce559fddc27d74306e828
https://pubmed.ncbi.nlm.nih.gov/25692008
https://pubmed.ncbi.nlm.nih.gov/25692008
Publikováno v:
European journal of pharmacology. 718(1-3)
Increased expressions of cyclooxygenase-2 (COX-2) and its downstream metabolite, prostaglandin E2 (PGE2), are well documented events in the development of colorectal cancer. Interestingly, PGE2 itself can induce the expression of COX-2 thereby creati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b0283ca8ba91a85da434607fb58178
https://pubmed.ncbi.nlm.nih.gov/23973650
https://pubmed.ncbi.nlm.nih.gov/23973650