Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Naofumi Seira"'
Autor:
Masato Mashimo, Asuka Shimizu, Aimi Mori, Ayaka Hamaguchi, Keijo Fukushima, Naofumi Seira, Takeshi Fujii, Hiromichi Fujino
Publikováno v:
Biochemical and Biophysical Research Communications. 623:133-139
E type prostanoid 4 (EP4) receptors and their signaling pathways have been implicated in the development and malignant transformation of colorectal cancer. We herein demonstrated that the mono(ADP-ribosyl)ation of histone deacetylase (HDAC)1 and HDAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec41cc08f1f74a080e1ab9740042d178
https://doi.org/10.1016/j.bbrc.2022.07.055
https://doi.org/10.1016/j.bbrc.2022.07.055
Autor:
Akito Onishi, Akiko Higashiyama, Shunya Yanagawa, Naofumi Seira, John W Regan, Kento Ohkawachi, Masaya Denda, Keijo Fukushima, Akira Otaka, Hiromichi Fujino
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1cf61865e605d6e4c2a232df26846ab
https://doi.org/10.1254/jpssuppl.95.0_1-p-092
https://doi.org/10.1254/jpssuppl.95.0_1-p-092
Autor:
Makiko Wasai, John W. Regan, Yutaka Tamura, Naofumi Seira, Akiko Suganami, Takayoshi Arai, Hiromichi Fujino, Naoki Yanagisawa, Keijo Fukushima, Takuya Honda, Toshihiko Murayama, Naoto Yamaguchi
Publikováno v:
Biologicalpharmaceutical bulletin. 40(10)
Ministry of Education, Culture, Sports, Science and Technology of Japan [JP17K08308]; Center of Excellence (COE) program from Chiba University of Japan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b170f9d39330fc6bb73d2cd3ac3abb6
https://pubmed.ncbi.nlm.nih.gov/28966256
https://pubmed.ncbi.nlm.nih.gov/28966256
Autor:
Hiromichi Fujino, W John Regan, Keijo Fukushima, Masato Mashimo, Naoki Yanagisawa, Toshihiko Murayama, Kazuyuki Yamagata, Naoki Kurata, Yumi Araki, Hiroyuki Nakamura, Naofumi Seira
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fd48e0045e7e08cbcbe95580b5a4739
https://doi.org/10.1254/jpssuppl.92.0_2-p-125
https://doi.org/10.1254/jpssuppl.92.0_2-p-125
Autor:
Naoki Kurata, Yumi Araki, Keijo Fukushima, Hiromichi Fujino, Toshihiko Murayama, Naofumi Seira, Kazuyuki Yamagata, Masato Mashimo, Hiroyuki Nakamura, John W. Regan, Naoki Yanagisawa
Publikováno v:
Pharmacology Research & Perspectives
The up‐regulated expression of E‐type prostanoid (EP) 4 receptors has been implicated in carcinogenesis; however, the expression of EP4 receptors has also been reported to be weaker in tumor tissues than in normal tissues. Indeed, EP4 receptors h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8d99331d4730a4ab12fcadb0036eed
http://repo.lib.tokushima-u.ac.jp/115684
http://repo.lib.tokushima-u.ac.jp/115684
Autor:
Naoki Kurata, Yumi Araki, Hiromichi Fujino, Naofumi Seira, Toshihiko Murayama, John W. Regan, Hiroyuki Nakamura
Publikováno v:
European journal of pharmacology. 768
Approximately two decades have passed since E-type prostanoid 4 (EP4) receptors were cloned, and the signaling pathways mediated by these receptors have since been implicated in cancer development through the alliance of Gαi-protein/phosphatidylinos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2dfe3ec3e3213d7a7ffbe0ca606427
https://pubmed.ncbi.nlm.nih.gov/26518053
https://pubmed.ncbi.nlm.nih.gov/26518053
Autor:
Kenji Yoshida, Sho Otake, John W. Regan, Naofumi Seira, Hiromichi Fujino, Christopher M. Sanchez, Toshihiko Murayama
Publikováno v:
Pharmacology Research & Perspectives
Increases in prostaglandin E2 (PGE2) and cyclooxygenase-2 (COX-2) levels are features of colon cancer. Among the different E-type prostanoid receptor subtypes, EP4 receptors are considered to play a crucial role in carcinogenesis by, for example, ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6facbce4ce559fddc27d74306e828
https://pubmed.ncbi.nlm.nih.gov/25692008
https://pubmed.ncbi.nlm.nih.gov/25692008
Publikováno v:
European journal of pharmacology. 718(1-3)
Increased expressions of cyclooxygenase-2 (COX-2) and its downstream metabolite, prostaglandin E2 (PGE2), are well documented events in the development of colorectal cancer. Interestingly, PGE2 itself can induce the expression of COX-2 thereby creati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b0283ca8ba91a85da434607fb58178
https://pubmed.ncbi.nlm.nih.gov/23973650
https://pubmed.ncbi.nlm.nih.gov/23973650
Autor:
Seira, Naofumi1 (AUTHOR), Yamagata, Kazuyuki1 (AUTHOR), Fukushima, Keijo2 (AUTHOR), Araki, Yumi1,2 (AUTHOR), Kurata, Naoki1,2 (AUTHOR), Yanagisawa, Naoki1 (AUTHOR), Mashimo, Masato3 (AUTHOR), Nakamura, Hiroyuki1 (AUTHOR), Regan, John W.4 (AUTHOR), Murayama, Toshihiko1 (AUTHOR), Fujino, Hiromichi2 (AUTHOR) hfujino@tokushima-u.ac.jp
Publikováno v:
Pharmacology Research & Perspectives. Dec2018, Vol. 6 Issue 6, p1-N.PAG. 14p.
Autor:
Otake, Sho1, Yoshida, Kenji1, Seira, Naofumi1, Sanchez, Christopher M.2, Regan, John W.2, Fujino, Hiromichi1, Murayama, Toshihiko1
Publikováno v:
Pharmacology Research & Perspectives. Feb2015, Vol. 3 Issue 1, pn/a-N.PAG. 13p.