Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Naoe Kotomura"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss , Pp 101086- (2021)
Human CYP19 spans a region of chromosome 15 of approximately 130 kb and encodes aromatase, an enzyme required for estrogen synthesis. In the human granulosa cell-line KGN, there are seven open chromatin regions within the CYP19 locus. In this study,
Externí odkaz:
https://doaj.org/article/7d2b782ecdeb4a64b9557f171fb1cb24
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128282 (2015)
The human CYP19 gene encodes aromatase, which converts androgens to estrogens. CYP19 mRNA variants are transcribed mainly from three promoters. Quantitative RT-PCR was used to measure the relative amounts of each of the three transcripts and determin
Externí odkaz:
https://doaj.org/article/194d299d92b8482f8d7f692973aa4670
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss, Pp 101086-(2021)
Human CYP19 spans a region of chromosome 15 of approximately 130 kb and encodes aromatase, an enzyme required for estrogen synthesis. In the human granulosa cell-line KGN, there are seven open chromatin regions within the CYP19 locus. In this study,
Autor:
Itoshi Nikaido, Takeru Kameda, Yohei Sasagawa, Mana Umeda, Naoe Kotomura, Masayuki Abe, Hayato Yamashita, Yohei Shimono, Satoru Ishihara
Publikováno v:
Nucleic Acids Research
The ‘open’ and ‘compact’ regions of chromatin are considered to be regions of active and silent transcription, respectively. However, individual genes produce transcripts at different levels, suggesting that transcription output does not depe
Publikováno v:
Biochemistry and Biophysics Reports
Human CYP19 spans a region of chromosome 15 of approximately 130 kb and encodes aromatase, an enzyme required for estrogen synthesis. In the human granulosa cell-line KGN, there are seven open chromatin regions within the CYP19 locus. In this study,
Autor:
Katsunori Tanaka, Yota Murakami, Naoe Kotomura, Satoru Tsunemine, Hiromi Nakagawa, Masahiro Kuragano, Takahiro Asanuma
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 23(9)
Abp1 is a fission yeast CENP-B homologue that contributes to centromere function, silencing at pericentromeric heterochromatin and silencing of retrotransposons. We identified the sfh1 gene, encoding a core subunit of the fission yeast chromatin remo
Publikováno v:
Analytical biochemistry. 531
Ligation-mediated polymerase chain reaction (LM-PCR) is a common technique for amplification of a pool of DNA fragments. Here, a double-stranded oligonucleotide consisting of two primer sequences in back-to-back orientation was designed as an adapter
Autor:
Josefina Ocampo, Victor B. Zhurkin, Feng Cui, V. Nagarajavel, Tatiana Nikitina, David Clark, Naoe Kotomura, Tara Burke, Hope A. Cole
Publikováno v:
Nucleic Acids Research
Eukaryotic chromosomal DNA is assembled into regularly spaced nucleosomes, which play a central role in gene regulation by determining accessibility of control regions. The nucleosome contains ∼147 bp of DNA wrapped ∼1.7 times around a central co
Autor:
Satoru Ishihara, Osamu Gotoh, Koichi Ohba, Naoe Kotomura, Hajime Nawata, Masatoshi Nomura, Tokuo Mukai, Toshihiko Yanase, Rina Kimura, Ken Ichirou Morohashi, Hironori Yoshii
Publikováno v:
Biochemical and Biophysical Research Communications. 278:63-71
It has been demonstrated that the mammalian Ad4BP/SF-1 (NR5A1) gene is regulated precisely in sex, tissue, and developmental stage specific manners. To clarify the complex transcriptional regulation, we investigated in the present study whether the g
Publikováno v:
Biochemical and Biophysical Research Communications. 222:632-638
The chromatin structure of the ELP gene was analyzed by DNase I hypersensitivity. A strong DNase I hypersensitive site (Y1DH) was identified at the exon 1 region of the ELP gene in steroidogenic Y1 cells. A strong DNase 1 hypersensitive site (ECDH2)