Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Naoe Kaneko"'
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281746 (2023)
The apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)/caspase-1/interleukin(IL)-1β axis, also known as the inflammasome pathway, is indispensable for IL-1β activation in response to various pathogens or own damag
Externí odkaz:
https://doaj.org/article/4d441646a3254eafb531a90a5217e1c3
Autor:
Junya Masumoto, Wei Zhou, Shinnosuke Morikawa, Sho Hosokawa, Haruka Taguchi, Toshihiro Yamamoto, Mie Kurata, Naoe Kaneko
Publikováno v:
Inflammation and Regeneration, Vol 41, Iss 1, Pp 1-26 (2021)
Abstract The long battle between humans and various physical, chemical, and biological insults that cause cell injury (e.g., products of tissue damage, metabolites, and/or infections) have led to the evolution of various adaptive responses. These res
Externí odkaz:
https://doaj.org/article/70d7aff5e3b0451ab4273d60ce5b8351
Publikováno v:
Inflammation and Regeneration, Vol 39, Iss 1, Pp 1-16 (2019)
Abstract Interleukin-1, an inflammatory cytokine, is considered to have diverse physiological functions and pathological significances and play an important role in health and disease. In this decade, interleukin-1 family members have been expanding
Externí odkaz:
https://doaj.org/article/c80d78ccb25647a38d3e6b53951803df
Autor:
Ayaka Nakanishi, Naoe Kaneko, Hiroyuki Takeda, Tatsuya Sawasaki, Shinnosuke Morikawa, Wei Zhou, Mie Kurata, Toshihiro Yamamoto, Sheikh Mohammad Fazle Akbar, Tamotsu Zako, Junya Masumoto
Publikováno v:
Inflammation and Regeneration, Vol 38, Iss 1, Pp 1-8 (2018)
Abstract Background Alzheimer’s disease is a neurodegenerative disease characterized by the interstitial deposition of amyloid β (Aβ) plaque, which is thought to be related to chronic neuroinflammation. Aβ is known to make fibrils via oligomers
Externí odkaz:
https://doaj.org/article/1772f38fc6d44f489f0e14f9eaac811a
Autor:
Naoe Kaneko, Tomoyuki Iwasaki, Yuki Ito, Hiroyuki Takeda, Tatsuya Sawasaki, Shinnosuke Morikawa, Naoko Nakano, Mie Kurata, Junya Masumoto
Publikováno v:
Inflammation and Regeneration, Vol 37, Iss 1, Pp 1-7 (2017)
Abstract The inflammasome, typically consisting of a Nod-like receptor, apoptosis-associated speck-like protein, and pro-caspase-1, has recently been identified as a huge intracellular complex, which plays a crucial role in interleukin-1 maturation o
Externí odkaz:
https://doaj.org/article/4d10b2e62750477bbf886a534fde92db
Autor:
Naoe Kaneko, Yuki Ito, Tomoyuki Iwasaki, Hiroyuki Takeda, Tatsuya Sawasaki, Kiyoshi Migita, Kazunaga Agematsu, Tomohiro Koga, Atsushi Kawakami, Akihiro Yachie, Koh-ichiro Yoshiura, Shinnosuke Morikawa, Mie Kurata, Junya Masumoto
Publikováno v:
European Journal of Inflammation, Vol 15 (2017)
In the NLR family, pyrin domain containing 3 (NLRP3) is an intracellular pattern recognition receptor that activates pro-caspase-1, leading to IL-1β and IL-18 processing and activation in a large complex called the NLRP3 inflammasome. Since various
Externí odkaz:
https://doaj.org/article/2b4f051e8ddc4634a8aff09e6f57abfb
Publikováno v:
International journal of immunopathology and pharmacology. 36
IntroductionDialysis-related amyloidosis (DRA) caused by β2-microgloblin (B2M) fibrils is a serious complication for patients with kidney failure on long-term dialysis. Deposition of B2M amyloid fibrils is thought to be due not only to serum extrace
Autor:
Tomoyuki Iwasaki, Naoe Kaneko, Yuki Ito, Hiroyuki Takeda, Tatsuya Sawasaki, Toshio Heike, Kiyoshi Migita, Kazunaga Agematsu, Atsushi Kawakami, Shinnosuke Morikawa, Sho Mokuda, Mie Kurata, Junya Masumoto
Publikováno v:
The Scientific World Journal, Vol 2016 (2016)
Nucleotide-binding oligomerization domain-containing protein (Nod) 2 is an intracellular pattern recognition receptor, which recognizes muramyl dipeptide (N-Acetylmuramyl-L-Alanyl-D-Isoglutamine: MDP), a bacterial peptidoglycan component, and makes a
Externí odkaz:
https://doaj.org/article/725b492ae4d440729c24225fda611f23
Publikováno v:
Cell Death and Differentiation
Human death domain superfamily proteins (DDSPs) play important roles in many signaling pathways involved in cell death and inflammation. Disruption or constitutive activation of these DDSP interactions due to inherited gene mutations is closely relat
Autor:
Kiyoshi Migita, Takeshi Urano, Naoe Kaneko, Hiroyuki Takeda, Akihiro Yachie, Kazunaga Agematsu, Tomohiro Koga, Koh-ichiro Yoshiura, Tomonari Shigemura, Toshihiro Yamamoto, Takashi Yamazaki, Mie Kurata, Tatsuya Sawasaki, Junya Masumoto, Atsushi Kawakami
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
NLRP3, an intracellular pattern recognition receptor, recognizes numerous pathogens and/or its own damage-associated molecules, and forms complexes with the adaptor protein ASC. These complexes constitute the NLRP3 inflammasome, a platform for proces