Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Naoaki Shimizu"'
Autor:
Jun Nakamura, Masaomi Iyo, Ryoji Nishimura, Toshifumi Kishimoto, Naohisa Uchimura, Jun Ishigooka, Yasuo Fujii, Nakao Iwata, Naoaki Shimizu
Publikováno v:
Schizophrenia research. 161(2-3)
Objective This study was designed to evaluate efficacy and safety of aripiprazole once-monthly (AOM) by verifying non-inferiority of AOM to oral aripiprazole in Asian patients with schizophrenia. Method The study consisted of a screening phase and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec92d37c48de6eb0ce4c452972fdf20
https://pubmed.ncbi.nlm.nih.gov/25556976
https://pubmed.ncbi.nlm.nih.gov/25556976
Autor:
Ken-ichi Saeki, Naoaki Shimizu, Yutaka Kawazoe, Ryuichi Murakami, Hiroshi Kawai, Arihiro Kohara, Atsushi Hakura
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 441:205-213
Some 16 nitroquinolines (NQs) and their fluorinated derivatives were tested for mutagenicity in Salmonella typhimurium TA100 without S9 mix to investigate the effect of fluorine-substitution on the mutagenicity. These NQs consist of 5-NQs, 5-nitroqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7363291856c683c2df834842e991f1df
https://doi.org/10.1016/s1383-5718(99)00049-2
https://doi.org/10.1016/s1383-5718(99)00049-2
Publikováno v:
Biological and Pharmaceutical Bulletin. 20:727-731
Laser scanning confocal fluorescence microscopic analysis provided a direct evidence of the internalization of non-permeant Lucifer Yellow and a dextran of MW 4400 into leukemia L1210 cells when the cells were vortex-stirred in the presence of a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d51d387efb682457409100ab567209
https://doi.org/10.1248/bpb.20.727
https://doi.org/10.1248/bpb.20.727
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:1126-1129
As we previously reported, the cytotoxicity of bleomycin (BLM) toward cultured mammalian cells was extraordinarily potentiated when the cells and BLM were vortex-stirred for a few seconds in the presence of high molecular weight polyacrylic acid (PAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9325638a04dce341a98a3250b02ebf8d
https://doi.org/10.1248/bpb.19.1126
https://doi.org/10.1248/bpb.19.1126
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:1565-1569
The permeability of murine leukemia L1210 cells toward non-permeant fluorescent Lucifer Yellow (LY) was evaluated by flow cytometry following vortex-stirring of cells with LY in the presence of high molecular weight polyacrylic acid (A-119). Permeabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a630f41950d29b74e3e03b3f78dc16
https://doi.org/10.1248/bpb.19.1565
https://doi.org/10.1248/bpb.19.1565
Publikováno v:
Biological and Pharmaceutical Bulletin. 20:25-27
Bleomycin (BLM) cytotoxicity was greatly enhanced by vortex-stirring BLM and mammalian cells for a few seconds together with 1 to 10 microg/ml high molecular weight polyacrylic acid (A-119). When suspensions of murine leukemia P388 cells were injecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9c6e3df2662790106864afc1226c57
https://doi.org/10.1248/bpb.20.25
https://doi.org/10.1248/bpb.20.25
Autor:
Yutaka Kawazoe, Naoaki Shimizu
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:1023-1025
Using a new technique of vortex-stirring of cells with high molecular weight polyacrylic acid (A-119), non-permeant fluorescein isothiocyanate-labeled dextrans (FDs) of various molecular weights were tested to determine the degree of their internaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a0c3d4e16d2a4974c6fb741c37d444
https://doi.org/10.1248/bpb.19.1023
https://doi.org/10.1248/bpb.19.1023
Autor:
Naoaki Shimizu, Yutaka Kawazoe
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:484-486
Transient permeabilization was readily achieved by vortex-stirring cultured mammalian cells for a few seconds in the presence of 1 to 10 micrograms/ml of high molecular weight polyacrylic acid (PAA). This was demonstrated by an appreciable uptake by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2baf0310bfe5ef7b46ffb9ea1f2150
https://doi.org/10.1248/bpb.19.484
https://doi.org/10.1248/bpb.19.484
Autor:
Yutaka Kawazoe, Naoaki Shimizu
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:1533-1535
We previously reported that cultured mammalian cells are effectively permeabilized by vortex-stirring the cells with a high molecular weight polyacrylic acid. The present study revealed that the efficiency of permeabilization of a non-permeant dye, L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1395af768e8f5ebbabcf99341edce4
https://doi.org/10.1248/bpb.19.1533
https://doi.org/10.1248/bpb.19.1533
Autor:
Naoaki Shimizu, Naoki Yamamoto, Tsutomu Murakami, T. Naoe, Hideki Nakashima, Yutaka Kawazoe, Hiroshi Sakagami
Publikováno v:
Biological and Pharmaceutical Bulletin. 16:434-436
After the dehydrogenation polymer of p-coumaric acid, a synthetic lignin, was intravenously injected into mice, the serum was collected immediately, 15 min, 1 h, 5 h, and 24 h after the injection. The serum thus obtained was added to the assay medium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10828182ddf0f8346d9b123d1cc497d8
https://doi.org/10.1248/bpb.16.434
https://doi.org/10.1248/bpb.16.434