Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Naoaki Ohkubo"'
Autor:
Naoaki Ohkubo, Yusuke Miyazaki, Shingo Nakayamada, Shunsuke Fukuyo, Yoshino Inoue, Yurie Satoh-Kanda, Hiroaki Tanaka, Yasuyuki Todoroki, Hiroko Miyata, Atsushi Nagayasu, Masashi Funada, Hiroki Kobayashi, Hidenori Sakai, Shumpei Kosaka, Satsuki Matsunaga, Yukiko Tomoyose, Hirotsugu Nohara, Yoshiya Tanaka
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 5, Pp 1303-1319 (2024)
Abstract Introduction The study aimed to determine the efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) in the treatment of polymyalgia rheumatica (PMR) complicated by rheumatoid arthritis (RA). Methods Patients with
Externí odkaz:
https://doaj.org/article/4bf563ac6abb415f8bae6b44e3ae265f
Autor:
Tsutomu Takeuchi, Yoshiya Tanaka, Rangi Kandane-Rathnayake, Sang-Cheol Bae, Zhanguo Li, Shereen Oon, Vera Golder, Mandana Nikpour, Masayoshi Harigai, Yi-Hsing Chen, Zhuoli Zhang, Eric Morand, Chak Sing Lau, Sunil Kumar, Alberta Hoi, Sandra Navarra, Sean O’Neill, Michael Tee, Jun Kikuchi, Yanjie Hao, Shue Fen Luo, Yasuhiro Katsumata, Aisha Lateef, Laniyati Hamijoyo, Sargunan Sockalingam, Nicola Tugnet, Madelynn Chan, Jiacai Cho, Cherica Tee, Leonid Zamora, BMDB Basnayake, Fiona Goldblatt, Naoaki Ohkubo, Kristine (Pek Ling) Ng, Louthrenoo Worawit, Yeong-Jian Jan Wu, Annie Hui Nee Law
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/bdbf55b194f6481798620e562a199f17
Autor:
Tsutomu Takeuchi, Yoshiya Tanaka, Rangi Kandane-Rathnayake, Sang-Cheol Bae, Zhanguo Li, Shereen Oon, Vera Golder, Mandana Nikpour, Masayoshi Harigai, Yi-Hsing Chen, Zhuoli Zhang, Eric Morand, Chak Sing Lau, Worawit Louthrenoo, Sunil Kumar, Alberta Hoi, Sandra Navarra, Sean O’Neill, Shue-Fen Luo, Michael Tee, Jun Kikuchi, Yanjie Hao, Yasuhiro Katsumata, Aisha Lateef, Laniyati Hamijoyo, Sargunan Sockalingam, Nicola Tugnet, Evelyn Salido, Jiacai Cho, Nick Faelnar, Cherica Tee, Jaime Caro, Geoffrey Solano, Angelene Therese Magbitang-Santiago, Yeong-Jian J Wu, Leonid Zamora, BMDB Basnayake, Madelynn Chann, Fiona Goldblatt, Kristine Ng, Annie Law, Naoaki Ohkubo
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9ba436e8e09041e196bb50c304685d52
Autor:
Ippei Miyagawa, Shingo Nakayamada, Masanobu Ueno, Yusuke Miyazaki, Shigeru Iwata, Satoshi Kubo, Koshiro Sonomoto, Junpei Anan, Naoaki Ohkubo, Yoshino Inoue, Yoshiya Tanaka
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Background We explored whether serum cytokines could be used as biomarkers for optimal use of tumor necrosis factor inhibitors (TNF-i) and interleukin (IL)-17 inhibitors (IL-17-i) in patients with psoriatic arthritis (PsA). Methods In cohort
Externí odkaz:
https://doaj.org/article/a3c9e3bf0f3c4952839348a8578adc7b
Autor:
Rangi Kandane-Rathnayake, Worawit Louthrenoo, Alberta Hoi, Shue-Fen Luo, Yeong-Jian J. Wu, Yi-Hsing Chen, Jiacai Cho, Aisha Lateef, Laniyati Hamijoyo, Sandra V. Navarra, Leonid Zamora, Sargunan Sockalingam, Yuan An, Zhanguo Li, Yasuhiro Katsumata, Masayoshi Harigai, Yanjie Hao, Zhuoli Zhang, Jun Kikuchi, Tsutomu Takeuchi, B. M. D. B. Basnayake, Madelynn Chan, Kristine Pek Ling Ng, Nicola Tugnet, Sunil Kumar, Shereen Oon, Fiona Goldblatt, Sean O’Neill, Kathryn A. Gibson, Naoaki Ohkubo, Yoshiya Tanaka, Sang-Cheol Bae, Chak Sing Lau, Mandana Nikpour, Vera Golder, Eric F. Morand, For the Asia-Pacific Lupus Collaboration
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Background The unmet need in systemic lupus erythematosus (SLE) with the current standard of care is widely recognised, but few studies have quantified this. The recent definition of treat-to-target endpoints and other thresholds of uncontro
Externí odkaz:
https://doaj.org/article/461787ebe7cb4251a2a681718deb19b6
Autor:
He Hao, Shingo Nakayamada, Naoaki Ohkubo, Kaoru Yamagata, Mingzeng Zhang, Yu Shan, Shigeru Iwata, Tong Zhang, Yoshiya Tanaka
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-11 (2021)
Abstract Background The single nucleotide polymorphism (SNP) rs62324212, located in IL21 antisense RNA 1 (IL21-AS1), has been identified as a genetic risk variant associated with systemic lupus erythematosus (SLE). We aimed to probe the characteristi
Externí odkaz:
https://doaj.org/article/5dca6634e8194bb292af811221eec726
Autor:
Ippei Miyagawa, Shingo Nakayamada, Masanobu Ueno, Yusuke Miyazaki, Naoaki Ohkubo, Yoshino Inoue, Satoshi Kubo, Yoshiya Tanaka
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
PurposeWe validated the one-year effectiveness of strategic treatment with biological disease-modifying anti-rheumatic drugs (bDMARDs) based on peripheral T-lymphocytic phenotyping and explored the impact of treatment on T helper lymphocytic phenotyp
Externí odkaz:
https://doaj.org/article/3ed8631a55874c0abafe40ac4da0ecc1
Autor:
Kaoru Yamagata, Shingo Nakayamada, Tong Zhang, Anh Phuong Nguyen, Naoaki Ohkubo, Shigeru Iwata, Shigeaki Kato, Yoshiya Tanaka
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/753b823d180640f995dfde2ff57ad31b
Enhanced Fatty Acid Synthesis Leads to Subset Imbalance and IFN-γ Overproduction in T Helper 1 Cells
Autor:
Shigeru Iwata, Mingzeng Zhang, He Hao, Gulzhan Trimova, Maiko Hajime, Yusuke Miyazaki, Naoaki Ohkubo, Yurie Satoh Kanda, Yasuyuki Todoroki, Hiroko Miyata, Masanobu Ueno, Atsushi Nagayasu, Shingo Nakayamada, Kei Sakata, Yoshiya Tanaka
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Recent reports have shown the importance of IFN-γ and T-bet+ B cells in the pathology of SLE, suggesting the involvement of IFN-γ-producing T-bet+ CD4+ cells, i.e., Th1 cells. This study determined the changes in Th1 subsets with metabolic shift an
Externí odkaz:
https://doaj.org/article/95ad77e1a47f4bab91a607e8855e9819
Autor:
Kathryn Connelly, Rangi Kandane-Rathnayake, Alberta Hoi, Worawit Louthrenoo, Laniyati Hamijoyo, Jiacai Cho, Aisha Lateef, Shue Fen Luo, Yeong-Jian J Wu, Zhanguo Li, Sandra Navarra, Leonid Zamora, Sargunan Sockalingam, Yanjie Hao, Zhuoli Zhang, Yasuhiro Katsumata, Masayoshi Harigai, Shereen Oon, Madelynn Chan, Yi-Hsing Chen, Sang-Cheol Bae, Sean O'Neill, Fiona Goldblatt, Jun Kikuchi, Tsutomu Takeuchi, Kristine Pek Ling Ng, Nicola Tugnet, B M D B Basnayake, Naoaki Ohkubo, Yoshiya Tanaka, Chak Sing Lau, Mandana Nikpour, Vera Golder, Eric F Morand
Publikováno v:
The Lancet Rheumatology. 4:e831-e841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2fb5efa550e8026121aeff32fa98b45
https://doi.org/10.1016/s2665-9913(22)00307-1
https://doi.org/10.1016/s2665-9913(22)00307-1