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Catalysis and oxygen binding of Ec DOS: a haem-based oxygen-sensor enzyme from Escherichia coli

Autor: Atsunari Tanaka, Toru Shimizu, Jotaro Igarashi, Yukako Ishitsuka, Hiroto Takahashi, Kazuo Kobayashi, Nao Yokota

Publikováno v: The Journal of Biochemistry. 148:693-703

A phosphodiesterase (PDE) from Escherichia coli (Ec DOS) is a novel haem-based oxygen sensor enzyme. Binding of O(2) to the reduced haem in the sensor domain enhances PDE activity exerted by the catalytic domain. Kinetic analysis of oxygen-dependent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a51a5cdfdd8d39a4b32d5de8c340af
https://doi.org/10.1093/jb/mvq103

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Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a heme-regulated phosphodiesterase from Escherichia coli

Autor: Nao Yokota, Osamu Ito, Jotaro Igarashi, Hirofumi Kurokawa, Yasuyuki Araki, Toru Shimizu

Publikováno v: FEBS Journal. 273:1210-1223

The heme-regulated phosphodiesterase from Escherichia coli (Ec DOS), which is a heme redox-dependent enzyme, is active with a ferrous heme but inactive with a ferric heme. Global structural changes including axial ligand switching and a change in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd652dc9469cbdeb6bb03b29afb7ee1e
https://doi.org/10.1111/j.1742-4658.2006.05145.x

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DOS Ec , a Heme-Regulated Phosphodiesterase, Plays an Important Role in the Regulation of the Cyclic AMP Level in Escherichia coli

Autor: Tokiko Yoshimura-Suzuki, Ikuko Sagami, Hirofumi Kurokawa, Nao Yokota, Toru Shimizu

Publikováno v: Journal of Bacteriology. 187:6678-6682

Heme-regulated phosphodiesterase from Escherichia coli (DOS Ec ) catalyzes the hydrolysis of cyclic AMP (cAMP) in vitro and is regulated by the redox state of the bound heme. Changes in the redox state result in alterations in the three-dimensional s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898e93a00b01cf6f8521700a10c18e30
https://doi.org/10.1128/jb.187.19.6678-6682.2005

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Structure and physical properties of oxalato-based organic conductors

Autor: Nao Yokota, Gunzi Saito, T. Kondo

Publikováno v: Synthetic Metals. 103:1839

Oxalato based organic conductors were prepared with M(ox)2, M(ox)3 (M=Al, Cr, Cu, Pt, Fe) using BEDT-TTF, BEDO-TTF, TMTSF, and their crystallographic, electronic, and magnetic properties were investigated. Partial charge transferred compounds were ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08777d297c62f022d52dae4688f96c52
https://doi.org/10.1016/s0379-6779(98)00490-1

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