Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nao Sankoda"'
Autor:
Nao Sankoda, Wataru Tanabe, Akito Tanaka, Hirofumi Shibata, Knut Woltjen, Tsutomu Chiba, Hironori Haga, Yoshiharu Sakai, Masaki Mandai, Takuya Yamamoto, Yasuhiro Yamada, Shinji Uemoto, Yoshiya Kawaguchi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
How boundary regions form in the epithelia of tissues, for example, the squamous–columnar junction is unclear. Here, the authors identify the transcription factors Sox2 and Gata4 as specifying the transitional epithelium in the murine squamous–co
Externí odkaz:
https://doaj.org/article/d5b4d6d2648f4fb79f5c508bf941f035
Autor:
Hirofumi Shibata, Shingo Komura, Yosuke Yamada, Nao Sankoda, Akito Tanaka, Tomoyo Ukai, Mio Kabata, Satoko Sakurai, Bunya Kuze, Knut Woltjen, Hironori Haga, Yatsuji Ito, Yoshiya Kawaguchi, Takuya Yamamoto, Yasuhiro Yamada
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Cellular reprogramming and cancer development share properties. Here, the authors examine the impact of in vivo reprogramming on Kras-induced cancer and show reprogramming-mediated repression of somatic cell enhancers in conjunction with Kras mutatio
Externí odkaz:
https://doaj.org/article/e71dfb2ea18648a280e7955320885433
Autor:
Asahi Sato, Toshihiko Masui, Nao Sankoda, Kenzo Nakano, Yuichiro Uchida, Takayuki Anazawa, Kyoichi Takaori, Yoshiya Kawaguchi, Shinji Uemoto
Publikováno v:
Surgical Case Reports, Vol 3, Iss 1, Pp 1-5 (2017)
Abstract Background Although pancreatic neuroendocrine tumors generally have a far better prognosis relative to pancreatic cancer, the varied manifestations lead to treatment-related challenges. Everolimus therapy is generally recommended for patient
Externí odkaz:
https://doaj.org/article/c5f4add6cfad4f55bc23940525dcdb8e
Autor:
Yui Shimada-Takayama, Takayuki Yasuda, Tomoyo Ukai, Jumpei Taguchi, Manabu Ozawa, Nao Sankoda, Sho Ohta, Yasuhiro Yamada
Publikováno v:
Biochemical and Biophysical Research Communications. 599:43-50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba1d5ce24a72a58cb25380137a2b12e
https://doi.org/10.1016/j.bbrc.2022.02.005
https://doi.org/10.1016/j.bbrc.2022.02.005
Autor:
Michitada Hirano, Yusei So, Shin Tsunekawa, Mio Kabata, Sho Ohta, Hiroshi Sagara, Nao Sankoda, Jumpei Taguchi, Yosuke Yamada, Tomoyo Ukai, Makoto Kato, Jiro Nakamura, Manabu Ozawa, Takuya Yamamoto, Yasuhiro Yamada
Publikováno v:
Nature Metabolism. 4:254-268
β cells have a limited capacity for regeneration, which predisposes towards diabetes. Here, we show that, of the MYC family members, Mycl plays a key role in proliferation of pancreatic endocrine cells. Genetic ablation of Mycl causes a reduction in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac817dbb1660b2932d3b63eb45e0ed0
https://doi.org/10.1038/s42255-022-00530-y
https://doi.org/10.1038/s42255-022-00530-y
Autor:
Knut Woltjen, Nao Sankoda, Shinji Uemoto, Wataru Tanabe, Yoshiya Kawaguchi, Hironori Haga, Hirofumi Shibata, Tsutomu Chiba, Takuya Yamamoto, Akito Tanaka, Yoshiharu Sakai, Masaki Mandai, Yasuhiro Yamada
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The squamous–columnar junction (SCJ) is a boundary consisting of precisely positioned transitional epithelium between the squamous and columnar epithelium. Transitional epithelium is a hotspot for precancerous lesions, and is therefore clinically i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716401084b8a77e64ad6bb5720b554e7
https://doi.org/10.1038/s41467-021-20906-0
https://doi.org/10.1038/s41467-021-20906-0
Autor:
Kenji Ito, Kohei Nagata, Sho Ohta, Yutaka Matsuda, Tomoyo Ukai, Ichiro Yasuda, Akira Ota, Ryota Kobayashi, Mio Kabata, Nao Sankoda, Tatsuya Maeda, Knut Woltjen, Liying Yang, Reo Maruyama, Ryohei Katayama, Takuya Yamamoto, Yasuhiro Yamada
Publikováno v:
Cell Reports. 39:110721
The resistance to transcription factor-mediated reprogramming into pluripotent stem cells is one of the distinctive features of cancer cells. Here we dissect the profiles of reprogramming factor binding and the subsequent transcriptional response in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee853c319dbfdcabf2aa170de18fdfb4
https://doi.org/10.1016/j.celrep.2022.110721
https://doi.org/10.1016/j.celrep.2022.110721
Autor:
Hironori Haga, Hirofumi Shibata, Bunya Kuze, Mio Kabata, Shingo Komura, Takuya Yamamoto, Akito Tanaka, Nao Sankoda, Yosuke Yamada, Satoko Sakurai, Knut Woltjen, Tomoyo Ukai, Yoshiya Kawaguchi, Yasuhiro Yamada, Yatsuji Ito
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications
The faithful shutdown of the somatic program occurs in the early stage of reprogramming. Here, we examined the effect of in vivo reprogramming on Kras-induced cancer development. We show that the transient expression of reprogramming factors (1–3 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1aebe94651e3be872193e02628f1b8c
http://hdl.handle.net/2433/231318
http://hdl.handle.net/2433/231318
Autor:
Toshihiko Masui, Asahi Sato, Yoshiya Kawaguchi, Nao Sankoda, Yuichiro Uchida, Takayuki Anazawa, Kyoichi Takaori, Shinji Uemoto, Kenzo Nakano
Publikováno v:
Surgical Case Reports
Surgical Case Reports, Vol 3, Iss 1, Pp 1-5 (2017)
Surgical Case Reports, Vol 3, Iss 1, Pp 1-5 (2017)
Background Although pancreatic neuroendocrine tumors generally have a far better prognosis relative to pancreatic cancer, the varied manifestations lead to treatment-related challenges. Everolimus therapy is generally recommended for patients with ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c3960169d89bd96136e5fd2b860f7d
http://europepmc.org/articles/PMC5519517
http://europepmc.org/articles/PMC5519517