Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Nao Hosoda"'
Publikováno v:
ACS Omega, Vol 9, Iss 6, Pp 6873-6879 (2024)
Externí odkaz:
https://doaj.org/article/cc946a77a2a441149c431b5e9fc28dcf
Autor:
Ryoichi Sawazaki, Shunsuke Imai, Mariko Yokogawa, Nao Hosoda, Shin-ichi Hoshino, Muneyo Mio, Kazuhiro Mio, Ichio Shimada, Masanori Osawa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Eukaryotic mature mRNAs possess a poly adenylate tail (poly(A)), to which multiple molecules of poly(A)-binding protein C1 (PABPC1) bind. PABPC1 regulates translation and mRNA metabolism by binding to regulatory proteins. To understand funct
Externí odkaz:
https://doaj.org/article/72a8c212de0b4c6b858a335b08566f8e
Autor:
Takuto Nogimori, Koichi Ogami, Yuka Oishi, Ryoya Goda, Nao Hosoda, Yoshiaki Kitamura, Yukio Kitade, Shin-ichi Hoshino
Publikováno v:
Viruses, Vol 12, Iss 2, p 174 (2020)
The 2′-5′-oligoadenylate synthetase (OAS)/RNase L system protects hosts against pathogenic viruses through cleavage of the exogenous single-stranded RNA. In this system, an evolutionally conserved RNA quality control factor Dom34 (known as Pelota
Externí odkaz:
https://doaj.org/article/838ee9f5587e44f2bdccdbf020a55f99
Publikováno v:
Polymers, Vol 8, Iss 3, p 66 (2016)
This study deals with the fabrication of biodegradable porous materials from bacterial polyester, poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P3HB3HHx), via thermally induced phase separation. P3HB3HHx monoliths with topological porous structure w
Externí odkaz:
https://doaj.org/article/dc47a7c61ffc4b2f968aa0fbdf02a088
Publikováno v:
Biochemical and Biophysical Research Communications. 553:9-16
The RNA-binding protein Ataxin-2 regulates translation and mRNA stability through cytoplasmic polyadenylation of the targets. Here we newly identified DDX6 as a positive regulator of the cytoplasmic polyadenylation. Analysis of Ataxin-2 interactome u
Autor:
Koichi Ogami, Yuka Oishi, Kentaro Sakamoto, Mayu Okumura, Ryota Yamagishi, Takumi Inoue, Masaya Hibino, Takuto Nogimori, Natsumi Yamaguchi, Kazuya Furutachi, Nao Hosoda, Hiroto Inagaki, Shin-ichi Hoshino
Publikováno v:
Cell Reports. 41:111548
Translation of 5' terminal oligopyrimidine (TOP) mRNAs encoding the protein synthesis machinery is strictly regulated by an amino-acid-sensing mTOR pathway. However, its regulatory mechanism remains elusive. Here, we demonstrate that TOP mRNA transla
Publikováno v:
Biochemical and Biophysical Research Communications. 511:422-426
MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate gene expression at post-transcriptional level via translational repression and/or mRNA degradation. miRNAs are associated with many cellular processes, and down-regulati
Autor:
Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa
Publikováno v:
Journal of Biological Chemistry. 298:101844
Eukaryotic mRNAs possess a poly(A) tail at their 3'-end, to which poly(A)-binding protein C1 (PABPC1) binds and recruits other proteins that regulate translation. Enhanced poly(A)-dependent translation, which is also PABPC1 dependent, promotes cellul
Autor:
Takahiro Nagai, Sho Kawashima, Takuto Nogimori, Kyutatsu Nishiura, Yoshiaki Kitamura, Hiroaki Imataka, Shin-ichi Hoshino, Nao Hosoda, Yuka Oishi, Yukio Kitade
Publikováno v:
Nucleic Acids Research
The 2′-5′-oligoadenylate synthetase (OAS)/RNase L pathway is an innate immune system that protects hosts against pathogenic viruses and bacteria through cleavage of exogenous single-stranded RNA; however, this system's selective targeting mechani
Publikováno v:
J Biol Chem
The RNA-binding protein Ataxin-2 binds to and stabilizes a number of mRNA sequences, including that of the transactive response DNA-binding protein of 43 kDa (TDP-43). Ataxin-2 is additionally involved in several processes requiring translation, such