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pro vyhledávání: '"Nao Asakawa"'
Autor:
Carl P. Decicco, Nicole Stowell, George L. Trainor, Robert C. Newton, Nao Asakawa, Steven M. Friedman, Kimberly A. Solomon, Kim Harrison, Patricia K. Welch, Bin Jiang, Paul S. Watson, Maryanne B. Covington, Soo S. Ko, Eric A. Wadman, Paul Davies
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:5695-5699
Linear unselective CCR3 antagonist leads with IC(50) values in the 200 nM range were converted into low nM binding compounds selective at CCR3 by moving the piperidine nitrogen substituent to the carbon at the 2-position of the ring. Substitution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00d69b7b8609837c7fb5ea4f7a5b499
https://doi.org/10.1016/j.bmcl.2006.08.012
https://doi.org/10.1016/j.bmcl.2006.08.012
