Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nanyan Rena Zhang"'
Autor:
Peining Tao, Stacey Conarello, Thomas P. Wyche, Nanyan Rena Zhang, Keefe Chng, John Kang, Theodore R. Sana
Publikováno v:
Metabolites, Vol 14, Iss 3, p 159 (2024)
Type 2 diabetes (T2D) is a global public health issue characterized by excess weight, abdominal obesity, dyslipidemia, hyperglycemia, and a progressive increase in insulin resistance. Human population studies of T2D development and its effects on sys
Externí odkaz:
https://doaj.org/article/50ab0f0e80484fc1978aed52a6d43461
Autor:
Nanyan Rena Zhang, Nathan G. Hatcher, Kim Ekroos, Komal Kedia, Monika Kandebo, Jacob N. Marcus, Sean M. Smith, Kevin P. Bateman, Daniel S. Spellman
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 6, Pp 100218- (2022)
A major challenge of lipidomics is to determine and quantify the precise content of complex lipidomes to the exact lipid molecular species. Often, multiple methods are needed to achieve sufficient lipidomic coverage to make these determinations. Mult
Externí odkaz:
https://doaj.org/article/dab7af844e374932baf5dd7f758560ce
Autor:
Lanfang Zou, Nanyan Rena Zhang, Marissa Vavrek, Bingming Chen, Xiaodong Bu, Joseph P. Smith, Wendy Zhong, Nicole M. Ralbovsky, Catherine D. G. Hines
Publikováno v:
Talanta. 235:122725
Analysis of the spatial distribution of metals, metalloids, and non-metals in biological tissues is of significant interest in the life sciences, helping to illuminate the function and roles these elements play within various biological pathways. Che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13774b1f07ee4829723365fe6dc89da
https://doi.org/10.1016/j.talanta.2021.122725
https://doi.org/10.1016/j.talanta.2021.122725
Autor:
José A. Lebrón, Donna Lynch, Kristin Geddes, Stephen Pacchione, Hong Duong, Yutai Li, Warren E. Glaab, Alema Galijatovic-Idrizbegovic, Frank D. Sistare, Wen Kang, Raymond J. Gonzalez, Daniel J. Holder, Kyeongmi Cheon, Kara Pearson, Nanyan Rena Zhang, Alex M Tamburino, Michael J. Hafey, Raymond Evers, Keith Q. Tanis, Lisa LaFranco-Scheuch
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 170(1)
Inhibition of the bile salt export pump (BSEP) may be associated with clinical drug-induced liver injury, but is poorly predicted by preclinical animal models. Here we present the development of a novel rat model using siRNA knockdown (KD) of Bsep th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0bf4d9d28084bd888d7572b62cf84e
https://pubmed.ncbi.nlm.nih.gov/30903168
https://pubmed.ncbi.nlm.nih.gov/30903168
Autor:
Christopher R. Gibson, Stacey L. Polsky-Fisher, Lihang Yao, Nanyan Rena Zhang, Ronald G. Robinson, Jeffrey W. Schubert, John M. Sanders, Scott E. Wolkenberg, Pete H. Hutson, Nancy A. Sachs, Scott T. Harrison, Debra McLoughlin, Zhijian Zhao, James C. Barrow, Sean M. Smith, Monika Kandebo
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(12)
A series of N -heterocyclic pyridinone catechol- O -methyltransferase (COMT) inhibitors were synthesized. Physicochemical properties, including ligand lipophilic efficiency (LLE) and c log P , were used to guide compound design and attempt to improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bbebc8732cb49d22f101f002ebfabc
https://pubmed.ncbi.nlm.nih.gov/27133481
https://pubmed.ncbi.nlm.nih.gov/27133481
Autor:
Donald J. Graham, Steven W. Ludmerer, David B. Olsen, Nanyan Rena Zhang, Kenneth A. Koeplinger, Malcolm MacCoss, Daria J. Hazuda, Mary-Ellen Davies, Larry Handt, Steven S. Carroll
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:926-934
Hepatitis C virus (HCV) infects an estimated 170 million individuals worldwide and is associated with an increased incidence of liver fibrosis, cirrhosis, and hepatocellular carcinoma. Currently approved therapies to treat HCV infection consist of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc7fc654defa660808a6f908c677c21
https://doi.org/10.1128/aac.01032-08
https://doi.org/10.1128/aac.01032-08
Autor:
Nanyan Rena Zhang, William Bart Emary
Publikováno v:
Mass Spectrometry for Drug Discovery and Drug Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a31aae3c5412523c210f379c5017ee2b
https://doi.org/10.1002/9781118516157.ch2
https://doi.org/10.1002/9781118516157.ch2
Autor:
W. Bart Emary, Nanyan Rena Zhang
Publikováno v:
Bioanalysis. 3(22)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb3a6280498e2b3283d5b9d6b05eb58
https://pubmed.ncbi.nlm.nih.gov/22122595
https://pubmed.ncbi.nlm.nih.gov/22122595
Autor:
James M. Fujitaki, Nanyan Rena Zhang, Malcolm MacCoss, Kenneth A. Koeplinger, Serge H. Boyer, Laurence Handt, Steven S. Carroll, Zhili Sun, Paul D. van Poelje, David B. Olsen, David L. Linemeyer, K. Raja Reddy, Scott J. Hecker, Marissa Vavrek, Mark D. Erion
Publikováno v:
Antimicrobial agents and chemotherapy. 55(8)
Hepatitis C virus (HCV) infects an estimated 170 million individuals worldwide, and the current standard of care, a combination of pegylated interferon alpha and ribavirin, is efficacious in achieving sustained viral response in ∼50% of treated pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4541a47dfc2d40b4578e58c816ef70e
https://pubmed.ncbi.nlm.nih.gov/21628542
https://pubmed.ncbi.nlm.nih.gov/21628542
Autor:
David B. Olsen, Nanyan Rena Zhang, Nigel J. Liverton, Malcolm MacCoss, Larry Handt, Mary-Ellen Davies, Steven S. Carroll, Kenneth A. Koeplinger, Daria J. Hazuda, Steven W. Ludmerer, Donald J. Graham
Publikováno v:
Antimicrobial agents and chemotherapy. 55(2)
Efforts to develop novel, interferon-sparing therapies for treatment of chronic hepatitis C (HCV) infection are contingent on the ability of combination therapies consisting of direct antiviral inhibitors to achieve a sustained virologic response. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b84d84e9dfda05c7aa8ddab60728b4
https://pubmed.ncbi.nlm.nih.gov/21115793
https://pubmed.ncbi.nlm.nih.gov/21115793