Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nanxiong Yu"'
Autor:
Li-Shu Wang, Gary D. Stoner, Claire Seguin, Claudio M. Rocha, Kristen Stoner, Steven Chiu, Nanxiong Yu, Stephen S. Hecht, Steven G. Carmella
Publikováno v:
Journal of Agricultural and Food Chemistry. 58:3992-3995
Biodirected fractionation is used to identify the active inhibitory constituents in berries for esophageal cancer in rats. The present study was undertaken to determine if ellagitannins contribute to the chemopreventive activity of an alcohol/water-i
Autor:
Lorraine B. Anderson, Robyn M. Scherber, Pramod Upadhyaya, Nanxiong Yu, David Lahti, Stephen S. Hecht, Fekadu Kassie
Publikováno v:
Cancer Research. 67:6502-6511
We tested the chemopreventive efficacy of indole-3-carbinol (I3C), a constituent of Brassica vegetables, and its major condensation product, 3,3′-diindolylmethane (DIM), against lung tumorigenesis induced by a mixture of 4-(methylnitrosamino)-1-(3-
Publikováno v:
Chemical Research in Toxicology. 20:246-256
NNN (1) is an esophageal carcinogen in rats. 2'-Hydroxylation of NNN is believed to be the major bioactivation pathway for NNN tumorigenicity. (S)-NNN is preferentially metabolized by 2'-hydroxylation in cultured rat esophagus, whereas there is no pr
Autor:
Gary R. Gray, Nanxiong Yu
Publikováno v:
Carbohydrate Research. 312:225-231
The degree of substitution (ds) and the distribution pattern of the two ester substituents in commercial samples of cellulose acetate–butyrate (CAB) were determined by sequential neutral methylation, direct reductive cleavage and in situ acetylatio
Autor:
Gary R. Gray, Nanxiong Yu
Publikováno v:
Carbohydrate Research. 313:29-36
The degree of substitution (ds) and the distribution pattern of the two ester substituents in commercial samples of cellulose acetate–propionate (CAP) were determined by sequential neutral methylation, direct reductive cleavage, and in situ acetyla
Autor:
Nanxiong Yu, Gary R. Gray
Publikováno v:
ChemInform. 30
The degree of substitution (ds) and the distribution pattern of the two ester substituents in commercial samples of cellulose acetate–butyrate (CAB) were determined by sequential neutral methylation, direct reductive cleavage and in situ acetylatio
Autor:
Claudio M. Rocha, Li-Shu Wang, Colleen McIntyre, Gary D. Stoner, Steven G. Carmella, John F. Lechner, Bethany Larue, Stephen S. Hecht, Cassandra Henry, Nanxiong Yu
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 2(1)
Diets containing freeze-dried black raspberries (BRB) suppress the development of N-nitrosomethylbenzylamine (NMBA)–induced tumors in the rat esophagus. Using bioassay-directed fractionation, the anthocyanins in BRB were found to be the most active
Publikováno v:
Chemical research in toxicology. 20(2)
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK, 1) and its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL, 2) are both potent pulmonary carcinogens in rats. The metabolism of NNK to NNAL is stereoselective and reversible, with (
Autor:
Mingyao Wang, Li Chen, Nanxiong Yu, J. Bradley Hochalter, Peter W. Villalta, Stephen S. Hecht
Publikováno v:
Chemical research in toxicology. 19(2)
Acetaldehyde, an ubiquitous mutagen and carcinogen, could be involved in human cancer etiology. Because DNA adducts are important in carcinogenesis, we have used liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) to
Autor:
Pramod Upadhyaya, Guang Cheng, Mingyao Wang, Nanxiong Yu, Peter W. Villalta, Shana J. Sturla, Stephen S. Hecht
Publikováno v:
Chemical research in toxicology. 17(5)
Metabolic hydroxylation of the methyl group of the tobacco specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) results in the formation of intermediates that