Same data, different conclusions: Radical dispersion in empirical results when independent analysts operationalize and test the same hypothesis

Autor: Schweinsberg, M., Feldman, M., Staub, N., van den Akker, O.R., van Aert, R.C.M., van Assen, M.A.L.M., Liu, Y., Althoff, T., Heer, J., Kale, A., Mohamed, Z., Amireh, H., Venkatesh Prasad, V., Bernstein, A., Robinson, E., Snellman, K., Sommer, S.A., Otner, S.M.G., Robinson, D.A., Madan, N., Silberzahn, R., Goldstein, P., Tierney, W., Murase, T., Mandl, B., Viganola, D., Strobl, C., Schaumans, C.B.C., Kelchtermans, S., Naseeb, C., Mason Garrison, S., Yarkoni, T., Richard Chan, C. S., Adie, P., Alaburda, P., Albers, C., Alspaugh, S., Alstott, J., Nelson, A.A., Ariño de la Rubia, E., Arzi, A., Bahník, Š., Baik, J., Winther Balling, L., Banker, S., Baranger, D.A.A., Barr, D.J., Barros-Rivera, B., Bauer, M., Blaise, E., Boelen, L., Bohle Carbonell, K., Briers, R.A., Burkhard, O., Canela, M.A., Castrillo, L., Catlett, T., Chen, O., Clark, M., Cohn, B., Coppock, A., Cugueró-Escofet, N., Curran, P.G., Cyrus-Lai, W., Dai, D., Valentino Dalla Riva, G., Danielsson, H., Russo, R.d.F.S.M., de Silva, N., Derungs, C., Dondelinger, F., Duarte de Souza, C., Tyson Dube, B., Dubova, M., Dunn, B.M., Edelsbrunner, P.A., Finley, S., Fox, N., Gnambs, T., Gong, Y., Grand, E., Greenawalt, B., Han, D., Hanel, P.H.P., Hong, A.B., Hood, D., Hsueh, J., Huang, L., Hui, K.N., Hultman, K.A., Javaid, A., Ji Jiang, L., Jong, J., Kamdar, J., Kane, D., Kappler, G., Kaszubowski, E., Kavanagh, C.M., Khabsa, M., Kleinberg, B., Kouros, J., Krause, H., Krypotos, A.M., Lavbič, D., Ling Lee, R., Leffel, T., Yang Lim, W., Liverani, S., Loh, B., Lønsmann, D., Wei Low, J., Lu, A., MacDonald, K., Madan, C.R., Hjorth Madsen, L., Maimone, C., Mangold, A., Marshall, A., Matskewich, H.E., Mavon, K., McLain, K.L., McNamara, A.A., McNeill, M., Mertens, U., Miller, D., Moore, B., Moore, A., Nantz, E., Nasrullah, Z., Nejkovic, V., Nell, C.S., Nilsonne, G., Nolan, R., O'Brien, C.E., O'Neill, P., O'Shea, K., Olita, T., Otterbacher, J., Palsetia, D., Pereira, B., Pozdniakov, I., Protzko, J., Reyt, J.N., Riddle, T., (Akmal) Ridhwan Omar Ali, A., Ropovik, I., Rosenberg, J.M., Rothen, S., Schulte-Mecklenbeck, M., Sharma, N., Shotwell, G., Skarzynski, M., Stedden, W., Stodden, V., Stoffel, M.A., Stoltzman, S., Subbaiah, S., Tatman, R., Thibodeau, P.H., Tomkins, S., Valdivia, A., Druijff-van de Woestijne, G.B., Viana, L., Villesèche, F., Wadsworth, W.D., Wanders, F., Watts, K., Wells, J.D., Whelpley, C.E., Won, A., Wu, L., Yip, A., Youngflesh, C., Yu, J.C., Zandian, A., Zhang, L., Zibman, C., Uhlmann, E.L., Social Networks, Solidarity and Inequality, Leerstoel Buskens, Structural geology and EM, Experimental psychopathology, Leerstoel Engelhard

Publikováno v: Organizational Behavior and Human Decision Processes, 165, 228-249. Academic Press Inc.
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Organizational Behavior and Human Decision Processes, 165
Schweinsberg, M, Feldman, M, Staub, N, van den Akker, O R, van Aert, R C M, van Assen, M A L M, Liu, Y, Althoff, T, Heer, J, Kale, A, Mohamed, Z, Amireh, H, Venkatesh Prasad, V, Bernstein, A, Robinson, E, Snellman, K, Amy Sommer, S, Otner, S M G, Robinson, D, Madan, N, Silberzahn, R, Goldstein, P, Tierney, W, Murase, T, Mandl, B, Viganola, D, Strobl, C, Schaumans, C B C, Naseeb, C, Mason Garrison, S, Yarkoni, T, Richard Chan, C S, Adie, P, Alaburda, P, Albers, C, Alspaugh, S, Alstott, J, Nelson, A A, Ariño de la Rubia, E, Arzi, A, Bahník, Š, Baik, J, Winther Balling, L, Banker, S, AA Baranger, D, Barr, D J, Barros-Rivera, B, Bauer, M, Blaise, E, Boelen, L, Bohle Carbonell, K, Briers, R A, Burkhard, O, Canela, M A, Castrillo, L, Catlett, T, Chen, O, Clark, M, Cohn, B, Coppock, A, Cugueró-Escofet, N, Curran, P G, Cyrus-Lai, W, Dai, D, Valentino Dalla Riva, G, Danielsson, H, Russo, R D F S M, de Silva, N, Derungs, C, Dondelinger, F, Duarte de Souza, C, Tyson Dube, B, Dubova, M, Mark Dunn, B, Adriaan Edelsbrunner, P, Finley, S, Fox, N, Gnambs, T, Gong, Y, Grand, E, Greenawalt, B, Han, D, Hanel, P H P, Hong, A B, Hood, D, Hsueh, J, Huang, L, Hui, K N, Hultman, K A, Javaid, A, Ji Jiang, L, Jong, J, Kamdar, J, Kane, D, Kappler, G, Kaszubowski, E, Kavanagh, C M, Khabsa, M, Kleinberg, B, Kouros, J, Krause, H, Krypotos, A M, Lavbič, D, Ling Lee, R, Leffel, T, Yang Lim, W, Liverani, S, Loh, B, Lønsmann, D, Wei Low, J, Lu, A, MacDonald, K, Madan, C R, Hjorth Madsen, L, Maimone, C, Mangold, A, Marshall, A, Ester Matskewich, H, Mavon, K, McLain, K L, McNamara, A A, McNeill, M, Mertens, U, Miller, D, Moore, B, Moore, A, Nantz, E, Nasrullah, Z, Nejkovic, V, Nell, C S, Arthur Nelson, A, Nilsonne, G, Nolan, R, O'Brien, C E, O'Neill, P, O'Shea, K, Olita, T, Otterbacher, J, Palsetia, D, Pereira, B, Pozdniakov, I, Protzko, J, Reyt, J N, Riddle, T, (Akmal) Ridhwan Omar Ali, A, Ropovik, I, Rosenberg, J M, Rothen, S, Schulte-Mecklenbeck, M, Sharma, N, Shotwell, G, Skarzynski, M, Stedden, W, Stodden, V, Stoffel, M A, Stoltzman, S, Subbaiah, S, Tatman, R, Thibodeau, P H, Tomkins, S, Valdivia, A, Druijff-van de Woestijne, G B, Viana, L, Villesèche, F, Duncan Wadsworth, W, Wanders, F, Watts, K, Wells, J D, Whelpley, C E, Won, A, Wu, L, Yip, A, Youngflesh, C, Yu, J C, Zandian, A, Zhang, L, Zibman, C & Luis Uhlmann, E 2021, ' Same data, different conclusions : Radical dispersion in empirical results when independent analysts operationalize and test the same hypothesis ', Organizational Behavior and Human Decision Processes, vol. 165, pp. 228-249 . https://doi.org/10.1016/j.obhdp.2021.02.003
Organizational Behavior and Human Decision Processes, 165, 228-249. ACADEMIC PRESS INC ELSEVIER SCIENCE
Schweinsberg, Martin; Feldman, Michael; Staub, Nicola; van den Akker, Olmo R.; van Aert, Robbie C.M.; van Assen, Marcel A.L.M.; Liu, Yang; Althoff, Tim; Heer, Jeffrey; Kale, Alex; Mohamed, Zainab; Amireh, Hashem; Venkatesh Prasad, Vaishali; Bernstein, Abraham; Robinson, Emily; Snellman, Kaisa; Amy Sommer, S.; Otner, Sarah M.G.; Robinson, David; Madan, Nikhil; ... (2021). Same data, different conclusions: Radical dispersion in empirical results when independent analysts operationalize and test the same hypothesis. Organizational behavior and human decision processes, 165, pp. 228-249. Elsevier 10.1016/j.obhdp.2021.02.003
Organizational Behavior and Human Decision Processes, 165, 228. Academic Press Inc.
Organizational Behavior and Human Decision Processes

The project was funded by a research grant from INSEAD and was also supported by the Swiss National Science Foundation under grant number 143411.
In this crowdsourced initiative, independent analysts used the same dataset to test two hypotheses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a3073e310e26f20b83ba377741a061

Effects of baricitinib on lipid, apolipoprotein, and lipoprotein particle profiles in a phase 2b study in patients with active rheumatoid arthritis

Autor: Kremer, J, Genovese, MC, Keystone, E, Taylor, P, Zuckerman, SH, Ruotolo, G, Schlichting, DE, Crotzer, VL, Nantz, E, Beattie, SD, Macias, WL

Objective: To assess the effects of baricitinib on lipid profile in patients with moderate-to-severe rheumatoid arthritis. Methods: Once-daily baricitinib (1, 2, 4, or 8-mg) or placebo was studied in 301 randomized patients. Changes in lipid profile,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::492d95ea4fb0cd492c14e66201c7312e
https://ora.ox.ac.uk/objects/uuid:9b4a686d-7b65-4a06-8d0c-240b0c107946

Increases in Serum Cholesterol with Baricitinib Treatment are Associated with Favorable Changes in Apolipoprotein Content and with Improvement in DAS28-CRP in Patients with Rheumatoid Arthritis

Autor: Kremer, JM, Genovese, MC, Keystone, E, Taylor, P, Zuckerman, SH, Schlichting, D, Nantz, E, Beattie, S, Macias, W, Holzkämper, T

Publikováno v: 43. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 29. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 25. wissenschaftliche Jahrestagung der Gesellschaft für Kinder-und Jugendrheumatologie (GKJR); 20150902-20150905; Bremen; DOCRA.23 /20150901/

Introduction: Treatment with baricitinib, an oral JAK1/JAK2 inhibitor, demonstrated improvements in signs and symptoms of RA through 52 wks in a Phase 2b study [1] and also in dose- and time-dependent changes in serum lipids, LDL particle size, and H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef68f114925f94bde112a58756ff64fd

Effects of Baricitinib on Lipid, Apolipoprotein, and Lipoprotein Particle Profiles in a Phase IIb Study of Patients With Active Rheumatoid Arthritis.

Autor: Kremer JM; Albany Medical College, Albany, New York., Genovese MC; Stanford University Medical Center, Palo Alto, California., Keystone E; University of Toronto, Toronto, Ontario, Canada., Taylor PC; University of Oxford, Oxford, UK., Zuckerman SH; Eli Lilly and Company, Indianapolis, Indiana., Ruotolo G; Eli Lilly and Company, Indianapolis, Indiana., Schlichting DE; Eli Lilly and Company, Indianapolis, Indiana., Crotzer VL; Eli Lilly and Company, Indianapolis, Indiana., Nantz E; Eli Lilly and Company, Indianapolis, Indiana., Beattie SD; Eli Lilly and Company, Indianapolis, Indiana., Macias WL; Eli Lilly and Company, Indianapolis, Indiana.

Publikováno v: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2017 May; Vol. 69 (5), pp. 943-952.

Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications.

Autor: Hubbard, Erika L.^1,2 (AUTHOR) erika.hubbard@ampelbiosolutions.com, Bachali, Prathyusha^1,2 (AUTHOR), Kingsmore, Kathryn M.^1,2 (AUTHOR), He, Yisha³ (AUTHOR), Catalina, Michelle D.⁴ (AUTHOR), Grammer, Amrie C.^1,2 (AUTHOR), Lipsky, Peter E.^1,2 (AUTHOR)

Publikováno v: Genome Medicine. 10/16/2023, Vol. 15 Issue 1, p1-23. 23p.