Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nantharat Pearnchob"'
Autor:
Valerie Hoffart, Nantharat Pearnchob, Roland Bodmeier, Mathias Walther, Mesut Ciper, Martin Körber, Ross James Macrae
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 78:447-454
Weakly basic drugs and their salts exhibit a decrease in aqueous solubility at higher pH, which can result in pH-dependent or even incomplete release of these drugs from extended release formulations. The objective of this study was to evaluate strat
Autor:
Nantharat Pearnchob, Roland Bodmeier
Publikováno v:
Pharmaceutical Research. 20:1970-1976
Purpose. To develop a novel powder coating technology for extended-release pellets based on the acrylic polymer, Eudragit® RS. Methods. A mixture of micronized Eudragit® RS plus talc and a liquid feed (plasticizer plus binder solution) were sprayed
Publikováno v:
Drug Development and Industrial Pharmacy. 29:925-938
Shellac is a natural polymer, which is used as enteric coating material in pharmaceutical applications. The major objective of the present study was to investigate the potential of shellac for other purposes, namely to provide moisture-protective and
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 94(2-3)
Shellac is a natural enteric polymer, which results in good gastric resistance; however, it often dissolves too slowly in intestinal fluids. The objective of this study was to improve the disintegration of shellac-coated soft gelatin capsules in simu
Autor:
Roland Bodmeier, Nantharat Pearnchob
Publikováno v:
International journal of pharmaceutics. 268(1-2)
Pellets were coated with ethylcellulose powder to achieve extended release. The film forming ability of ethylcellulose powder and the effect of formulation factors (plasticizer type and concentration) and curing conditions (curing temperature and tim
Autor:
Nantharat Pearnchob, Roland Bodmeier
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 56(3)
Drug-layered pellets were coated with micronized polymer powders (Eudragit® RS, ethylcellulose, and shellac) by a dry powder coating technique as an alternative to organic- and aqueous-based coatings (Eudragit® RS 30D, Aquacoat® ECD) were investig