Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nanthakumar Subramaniam"'
Autor:
Michael Downes, Christopher Liddle, Ronald M. Evans, Annette R. Atkins, Sally Coulter, Caroline Wilson, Renuka Rao, Mara H. Sherman, Nanthakumar Subramaniam
AMP-activated protein kinase (AMPK) regulates lipid, cholesterol, and glucose metabolism in specialized metabolic tissues, such as muscle, liver, and adipose tissue. Agents that activate AMPK, such as metformin and 5-aminoimidazole-4-carboxamide-1-be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::213b5b6b0bfd2dadfad7508faaa664c3
https://doi.org/10.1158/1940-6207.c.6544833
https://doi.org/10.1158/1940-6207.c.6544833
Autor:
Michael Downes, Christopher Liddle, Ronald M. Evans, Annette R. Atkins, Sally Coulter, Caroline Wilson, Renuka Rao, Mara H. Sherman, Nanthakumar Subramaniam
PDF file - 104K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b58ed366356f61325df65f6a864636
https://doi.org/10.1158/1940-6207.22525626
https://doi.org/10.1158/1940-6207.22525626
Autor:
Annette R. Atkins, Ronald M. Evans, Michael Downes, Nanthakumar Subramaniam, Christopher Liddle, Sally Coulter, Renuka Rao, Caroline L. Wilson, Mara H. Sherman
Publikováno v:
Cancer Prevention Research. 5:553-561
AMP-activated protein kinase (AMPK) regulates lipid, cholesterol, and glucose metabolism in specialized metabolic tissues, such as muscle, liver, and adipose tissue. Agents that activate AMPK, such as metformin and 5-aminoimidazole-4-carboxamide-1-be
Autor:
John A. Eisman, Edith M. Gardiner, Michael J. Hayman, Nanthakumar Subramaniam, Gary M. Leong, Janelle B. Barry, Tomoshige Kino, Laura L. Issa, Paul H. Driggers
Publikováno v:
Biochemical and Biophysical Research Communications. 315:1070-1076
Ski-interacting protein (SKIP), a vitamin D receptor (VDR) coactivator, also functions as a repressor in Notch signalling in association with the corepressor SMRT. Here we show that SKIP bifunctionally modulates (activates or represses) Retinoid-X re
Autor:
Patsie Polly, Peter W. Gunning, Edna C. Hardeman, Laura L. Issa, Nanthakumar Subramaniam, Enoch S. E. Tay, Kim L. Guven
Publikováno v:
Biochemical Journal. 374:359-367
A human MusTRD [muscle TFII-I repeat domain (RD)-containing protein] isoform was originally identified in a yeast one-hybrid screen as a protein that binds the slow fibre-specific enhancer of the muscle gene troponin I slow [O'Mahoney, Guven, Lin, Jo
Autor:
Nanthakumar Subramaniam, Gloria Velasco, Nigel C. Bennett, Cameron J. McDonald, V. Nathan Subramaniam, John D. Hooper, L. Ostini, Daniel F. Wallace
Publikováno v:
American Journal of Physiology-Cell Physiology
Mutations in the TMPRSS6 gene are associated with severe iron-refractory iron deficiency anemia resulting from an overexpression of hepcidin, the key regulator of iron homeostasis. The matriptase (MT)-2 protein (encoded by the TMPRSS6 gene) regulates
Autor:
Laura L. Issa, Patsie Polly, Leila M. Haddadi, Nanthakumar Subramaniam, Enoch S. E. Tay, Stephen J. Palmer, Edna C. Hardeman
Publikováno v:
The Journal of biological chemistry. 278(38)
The novel transcription factor hMusTRD1alpha1 (human muscle TFII-I repeat domain-containing protein 1alpha1; previously named MusTRD1; O'Mahoney, J. V., Guven, K. L., Lin, J., Joya, J. E., Robinson, C. S., Wade, R. P., and Hardeman, E. C. (1998) Mol.
Glucocorticoid (GC) signalling influences the response of the cell to a number of other signals via a mechanism referred to as ‘cross-talk'. This cross-talk may act at several levels, including an interaction between the transcription factors invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d8393e7fa206872d195ed4f1c20cd1
https://europepmc.org/articles/PMC1223238/
https://europepmc.org/articles/PMC1223238/
Autor:
John A. Eisman, Colette Fong, Alexander P. Kouzmenko, Judith Flanagan, Terrie-Anne Cock, Nanthakumar Subramaniam, Gary M. Leong
Publikováno v:
The Journal of biological chemistry. 276(19)
1,25-Dihydroxyvitamin D(3) (vitamin D) and transforming growth factor-beta (TGF-beta) regulate diverse biological processes including cell proliferation and differentiation through modulation of the expression of target genes. Members of the Smad fam
Autor:
Alexander P. Kouzmenko, John A. Eisman, Jonine Figueroa, Nanthakumar Subramaniam, Judith Flanagan, Gary M. Leong, Michael J. Hayman
Publikováno v:
The Journal of biological chemistry. 276(21)
Transforming growth factor-beta (TGF-beta) signaling requires the action of Smad proteins in association with other DNA-binding factors and coactivator and corepressor proteins to modulate target gene transcription. Smad2 and Smad3 both associate wit