Zobrazeno 1 - 10
of 600
pro vyhledávání: '"Nanosponge"'
Autor:
Durgaramani Sivadasan, Krishnaraju Venkatesan, Jamal Moideen Muthu Mohamed, Saud Alqahtani, Yahya I. Asiri, Mennatullah M. Faisal, Adel Ehab Ibrahim, Yahya Bin Abdullah Alrashdi, Farid Menaa, Sami El Deeb
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Loratadine (LoR) is a highly lipophilic and practically insoluble in water, hence having a low oral bioavailability. As it is formulated as topical gel, it competitively binds with the receptors, thus reducing the side-effects. The objective
Externí odkaz:
https://doaj.org/article/1316fe22211942c9a5bc8ebfb6058231
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Background The current investigation aimed to develop, optimise, and assess a mupirocin-loaded nanosponge-based topical delivery system for diabetic foot ulcer and to achieve prolonged drug release while improving drug deposition within the
Externí odkaz:
https://doaj.org/article/10ca28fdf0f74435a9993746f10dc4ae
Autor:
Qingbo Lv, Jun Lin, He Huang, Boxuan Ma, Wujiao Li, Jiawen Chen, Meihui Wang, Xiaoyu Wang, Guosheng Fu, Yun Xiao
Publikováno v:
Advanced Science, Vol 11, Iss 25, Pp n/a-n/a (2024)
Abstract Myocardial infarction (MI), a consequence of coronary artery occlusion, triggers the degradation of ferritin, resulting in elevated levels of free iron in the heart and thereby inducing ferroptosis. Targeting myocardial ferroptosis through t
Externí odkaz:
https://doaj.org/article/56a5235b152946ddadacfd0c3144de8e
Autor:
Claudiu Radu, Andreea Alexandra Olteanu, Corina Cristina Aramă, Mirela Mihăilă, Valentina Uivaroși
Publikováno v:
Applied Sciences, Vol 14, Iss 13, p 5441 (2024)
In the present study, the complexes of aluminum and gallium with 5-hydroxyflavone were evaluated for their interaction with cyclodextrin polymers, as well as for the pharmacological effect of their inclusion. The cyclodextrin polymers were synthesize
Externí odkaz:
https://doaj.org/article/909c717967de437e963061c4797378b4
Autor:
Honglan Wang, Huiwen Liu, Jia Li, Chunying Liu, Hui Chen, Junying Li, Chunyan Sun, Tao Guo, Zhiqing Pang, Bo Zhang, Yu Hu
Publikováno v:
Bioactive Materials, Vol 21, Iss , Pp 531-546 (2023)
Hemophagocytic lymphohistiocytosis (HLH) is a highly fatal condition with the positive feedback loop between continued immune cell activation and cytokine storm as the core mechanism to mediate multiple organ dysfunction. Inspired by macrophage membr
Externí odkaz:
https://doaj.org/article/28af2262c48f469fa8fa5b7049d5ac58
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3527 (2024)
Cyclodextrin-based nanosponges (CDNSs) are complex macromolecular structures composed of individual cyclodextrins (CDs) and nanochannels created between cross-linked CD units and cross-linkers. Due to their unique structural and physicochemical prope
Externí odkaz:
https://doaj.org/article/027eff6176eb42fa94ac0634ed8a8a7b
Autor:
Francesca Uberti, Francesco Trotta, Roberta Cavalli, Rebecca Galla, Fabrizio Caldera, Sara Ferrari, Simone Mulè, Arianna Brovero, Claudio Molinari, Pasquale Pagliaro, Claudia Penna
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2189 (2024)
Vitamin D3 (VitD3) plays a crucial role in various cellular functions through its receptor interaction. The biological activity of Vitamin D3 can vary based on its solubility and stability. Thus, the challenge lies in maximizing its biological effect
Externí odkaz:
https://doaj.org/article/aba801f395fc48cb8eb98001ce74d1c3
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