Zobrazeno 1 - 10
of 772
pro vyhledávání: '"Nanoassembly"'
Autor:
Yu Hou, Lin Zhu, Xiaofeng Ye, Qiaoying Ke, Qibin Zhang, Xiaowei Xie, Ji-gang Piao, Yinghui Wei
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Renal fibrosis is a progressive process associated with chronic kidney disease (CKD), contributing to impaired kidney function. Active constituents in traditional Chinese herbs, such as emodin (EMO) and asiatic acid (AA), exhibit
Externí odkaz:
https://doaj.org/article/ab90b1c1086641d5bd240524528d8c8f
Autor:
Fujun Yang, Shumeng Li, Qingyu Ji, Hongyuan Zhang, Mingyang Zhou, Yuequan Wang, Shenwu Zhang, Jin Sun, Zhonggui He, Cong Luo
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract The clinical translation of tumor hypoxia intervention modalities still falls short of expectation, restricted by poor biocompatibility of oxygen‐carrying materials, unsatisfactory oxygen loading performance, and abnormally high cellular o
Externí odkaz:
https://doaj.org/article/8845a15f197a4345aadea1f85625fcfc
Autor:
Zhilin Li, Qianfeng Zhang, Zhiqian Li, Long Ren, Dayi Pan, Qiyong Gong, Zhongwei Gu, Hao Cai, Kui Luo
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 2194-2209 (2024)
Despite the great potential of anti-PD-L1 antibodies for immunotherapy, their low response rate due to an immunosuppressive tumor microenvironment has hampered their application. To address this issue, we constructed a cell membrane-coated nanosystem
Externí odkaz:
https://doaj.org/article/70ce0f1e01b14ffc8c29e5c2c878ea83
Autor:
Ziqi Lin, Yuequan Wang, Wenwen Li, Fei Sun, Qingzhi Lv, Shenwu Zhang, Xiaohong Liu, Feng Qin, Cong Luo
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 4, Pp 100892- (2024)
Small-molecule prodrug nanoassembly technology with a unique advantage in off-target toxicity reduction has been widely used for antitumor drug delivery. However, prodrug activation remains a rate-limiting step for exerting therapeutic actions, which
Externí odkaz:
https://doaj.org/article/c473bb0289d241e1ab46ccdc69ffc4ff
Autor:
Lu Su, Kellie S. Dalby, Hannah Luehmann, Sussana A. Elkassih, Sangho Cho, Xun He, Lisa Detering, Yen-Nan Lin, Nari Kang, Dennis A. Moore, Richard Laforest, Guorong Sun, Yongjian Liu, Karen L. Wooley
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1660-1670 (2023)
To expand the single-dose duration over which noninvasive clinical and preclinical cancer imaging can be conducted with high sensitivity, and well-defined spatial and temporal resolutions, a facile strategy to prepare ultrasmall nanoparticulate X-ray
Externí odkaz:
https://doaj.org/article/e7261962bbb84ae9b003fc1dcfe14759
Autor:
Mengnan Zhao, Rujing Wang, Kunmeng Yang, Yuhong Jiang, Yachen Peng, Yuke Li, Zhen Zhang, Jianxun Ding, Sanjun Shi
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 916-941 (2023)
RNAs are involved in the crucial processes of disease progression and have emerged as powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of therapeutic RNA to the targeted location and precise detection of RNA markers
Externí odkaz:
https://doaj.org/article/a0d4f58595554074bbb3d34a30adf0c4
Autor:
Guanting Li, Qianhui Jin, Fengli Xia, Shuwen Fu, Xuanbo Zhang, Hongying Xiao, Chutong Tian, Qingzhi Lv, Jin Sun, Zhonggui He, Bingjun Sun
Publikováno v:
Acta Materia Medica, Vol 2, Iss 1, Pp 54-63 (2023)
The compound 7-ethyl-10-hydroxy-camptothecin (SN38) is a broad-spectrum antitumor agent whose applications are greatly limited by its poor solubility. Therefore, irinotecan, the hydrophilic derived prodrug of SN38, has been developed as the commercia
Externí odkaz:
https://doaj.org/article/ae6512a5df90477c8a75cb397dae81d1
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 3281-3290 (2022)
Photodynamic therapy (PDT) has been extensively investigated as a spatiotemporally noninvasive and controllable modality for cancer treatment. However, the intracellular antioxidant systems mainly consisting of thioredoxin (Trx) and glutathione (GSH)
Externí odkaz:
https://doaj.org/article/6e351dd2fca646f3b4e70ea0828815c3
Autor:
Rozhdestvenskiy Oleg Igorevich, Lalitha Yaragudipati Sri, Ikram Mohsin, Gupta Mridula, Jain Alok, Verma Raman, Sood Sumita
Publikováno v:
E3S Web of Conferences, Vol 588, p 02005 (2024)
By virtue of their unique properties at the nanoscale, nanomaterials have revolutionized the field of material science. The current work provides a thorough analysis of nanomaterials, classifying them into three main categories: nanoparticles, nanoso
Externí odkaz:
https://doaj.org/article/4863a0fa09514d35a473f6bec83b59ee
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