Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Nanna Sarvilinna"'
Autor:
Heli Kuisma, Simona Bramante, Kristiina Rajamäki, Lauri J. Sipilä, Eevi Kaasinen, Jaana Kaukomaa, Kimmo Palin, Netta Mäkinen, Jari Sjöberg, Nanna Sarvilinna, Jussi Taipale, Liisa Kauppi, Manuela Tumiati, Antti Hassinen, Janne Pitkäniemi, Jyrki Jalkanen, Sanna Heikkinen, Annukka Pasanen, Oskari Heikinheimo, Ralf Bützow, Niko Välimäki, Lauri A. Aaltonen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Many factors have been associated with chromosomal damage, including mechanical forces in a constrained cellular environment. Here the authors reveal an association between parity and chromosomal damage by analysing karyotypes of 1946 uterine leiomyo
Externí odkaz:
https://doaj.org/article/d2e867958c8a4229a73872634dd5e339
Autor:
Niko Välimäki, Heli Kuisma, Annukka Pasanen, Oskari Heikinheimo, Jari Sjöberg, Ralf Bützow, Nanna Sarvilinna, Hanna-Riikka Heinonen, Jaana Tolvanen, Simona Bramante, Tomas Tanskanen, Juha Auvinen, Outi Uimari, Amjad Alkodsi, Rainer Lehtonen, Eevi Kaasinen, Kimmo Palin, Lauri A Aaltonen
Publikováno v:
eLife, Vol 7 (2018)
Uterine leiomyomas (ULs) are benign tumors that are a major burden to women’s health. A genome-wide association study on 15,453 UL cases and 392,628 controls was performed, followed by replication of the genomic risk in six cohorts. Effects of the
Externí odkaz:
https://doaj.org/article/94e199383a454da09e3a65af3810b73f
Publikováno v:
Archives of Gynecology and Obstetrics.
Purpose Shoulder dystocia is an obstetric emergency with severe complications. Our objective was to evaluate the major pitfalls in the diagnostics of shoulder dystocia, diagnostic descriptions documented in medical records, use of obstetric maneuvers
Publikováno v:
Acta Obstetricia et Gynecologica Scandinavica. 100:538-547
INTRODUCTION Shoulder dystocia has remained an unpredictable and feared emergency in obstetrics. Some risk factors have been identified but nevertheless there is a lack of risk evaluation tools in clinical practice. The aim of this study was to evalu
Publikováno v:
Acta Obstetricia et Gynecologica Scandinavica. 96:372-381
Introduction In this study, we have assessed the changes in pregnancy outcomes following the implementation of national guidelines for gestational diabetes mellitus (GDM). These national guidelines changed the screening policy from risk-based to comp
Autor:
Nanna Sarvilinna, Lauri A. Aaltonen, Jaana Tolvanen, Hanna-Riikka Heinonen, Norma Frizzell, Anne Ahtikoski, Pia Vahteristo, Ralf Bützow, Miika Mehine, Outi Uimari, Esa Pitkänen, Netta Mäkinen, Salla Välipakka, Tuomas Heikkinen, Jari Sjöberg, Kati Kämpjärvi
Publikováno v:
British Journal of Cancer
Background: Uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer (HLRCC) patients are driven by fumarate hydratase (FH) inactivation or occasionally by mediator complex subunit 12 (MED12) mutations. The aim of this study was to ana
Autor:
Esa Pitkänen, Jari Sjöberg, Kati Kämpjärvi, Anna Vähärautio, Pia Vahteristo, Miika Mehine, Oskari Heikinheimo, Eevi Kaasinen, Annukka Pasanen, Nanna Sarvilinna, Ralf Bützow, Hanna-Riikka Heinonen, Netta Mäkinen, Mervi Aavikko, Lauri A. Aaltonen
Publikováno v:
Proceedings of the National Academy of Sciences. 113:1315-1320
Uterine leiomyomas are common benign smooth muscle tumors that impose a major burden on women's health. Recent sequencing studies have revealed recurrent and mutually exclusive mutations in leiomyomas, suggesting the involvement of molecularly distin
Publikováno v:
Genes, Chromosomes and Cancer. 55:215-226
Genome instability is a hallmark of many tumors and recently, next-generation sequencing methods have enabled analyses of tumor genomes at an unprecedented level. Studying rearrangement-prone chromosomal regions (putative “breakpoint hotspots”) i
Autor:
Kimmo Palin, Amjad Alkodsi, Rainer Lehtonen, Tomas Tanskanen, Nanna Sarvilinna, Niko Välimäki, Annukka Pasanen, Jaana Tolvanen, Hanna-Riikka Heinonen, Eevi Kaasinen, Juha Auvinen, Heli Kuisma, Jari Sjöberg, Lauri A. Aaltonen, Ralf Bützow, Outi Uimari, Simona Bramante, Oskari Heikinheimo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a821bde24d3a0979c9db9f29fa89b0f
https://doi.org/10.7554/elife.37110.047
https://doi.org/10.7554/elife.37110.047
Publikováno v:
Clinical Cancer Research. 25:GMM-050
High-grade serous ovarian cancer (HGS-OVCA) is the most common type of ovarian cancer. HGS-OVCA genomes are usually very complex and unstable. Many studies have addressed cytogenetic changes, and with the advent of high-throughput sequencing, complex