Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Nanna Fyhrquist"'
MeXposeA Modular Imaging Pipeline for the Quantitative Assessment of Cellular Metal Bioaccumulation
Autor:
Gabriel Braun, Martin Schaier, Paulina Werner, Sarah Theiner, Jürgen Zanghellini, Lukas Wisgrill, Nanna Fyhrquist, Gunda Koellensperger
Publikováno v:
JACS Au, Vol 4, Iss 6, Pp 2197-2210 (2024)
Externí odkaz:
https://doaj.org/article/7e3d0cf0d6e54cbb93058142b0a6e3bc
Autor:
Ying Yang, Peter Olah, Zoltan Radai, Guilherme Maia, Alexander Salava, Ville Salo, Jonathan Barker, Antti Lauerma, Björn Andersson, Bernhard Homey, Nanna Fyhrquist, Harri Alenius
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105222- (2024)
Summary: Background: Psoriasis (Pso) is a chronic inflammatory skin disease that poses both physical and psychological challenges. Dysbiosis of the skin microbiome has been implicated in Pso, yet a comprehensive multi-omics analysis of host-microbe i
Externí odkaz:
https://doaj.org/article/640fe0e353074af79b9a9929a2bd6beb
Autor:
Antonio Federico, Lena Möbus, Zeyad Al-Abdulraheem, Alisa Pavel, Vittorio Fortino, Giusy del Giudice, Harri Alenius, Nanna Fyhrquist, Dario Greco
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Atopic dermatitis (AD) is a prevalent chronic inflammatory skin disease whose pathophysiology involves the interplay between genetic and environmental factors, ultimately leading to dysfunction of the epidermis. While several trea
Externí odkaz:
https://doaj.org/article/8b2ab85eecfc497e92b3317b3f61f1f0
Autor:
Tari Haahtela, Harri Alenius, Petri Auvinen, Nanna Fyhrquist, Leena von Hertzen, Pekka Jousilahti, Piia Karisola, Tiina Laatikainen, Jenni Lehtimäki, Laura Paalanen, Lasse Ruokolainen, Kimmo Saarinen, Erkka Valovirta, Tuula Vasankari, Tiina Vlasoff, Marina Erhola, Jean Bousquet, Erkki Vartiainen, Mika J. Mäkelä
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
Contact with natural environments enriches the human microbiome, promotes immune balance and protects against allergies and inflammatory disorders. In Finland, the allergy & asthma epidemic became slowly visible in mid 1960s. After the World War II,
Externí odkaz:
https://doaj.org/article/c6e375d6f15d40ed8bff002ccf57bfb4
Autor:
Joseph Ndika, Piia Karisola, Vilma Lahti, Nanna Fyhrquist, Tiina Laatikainen, Tari Haahtela, Harri Alenius
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
BackgroundPreviously, we investigated skin microbiota and blood cell gene expression in Finnish and Russian teenagers with contrasting incidence of allergic conditions. The microbiota and transcriptomic signatures were distinctly different, with high
Externí odkaz:
https://doaj.org/article/c23ab8caec564a1ba27c2cbb6585cc82
Publikováno v:
Journal of Immunotoxicology, Vol 18, Iss 1, Pp 74-84 (2021)
Sensitization to a contact allergen brings with it a lifelong risk to develop allergic contact dermatitis. Inflammation is an important part of the skin sensitizing mechanism, and understanding how different haptens stimulate the immune system, as we
Externí odkaz:
https://doaj.org/article/aaabd4d77fe44a9fa38691c77d67d907
Autor:
Piia Karisola, Kati Palosuo, Victoria Hinkkanen, Lukas Wisgrill, Terhi Savinko, Nanna Fyhrquist, Harri Alenius, Mika J. Mäkelä
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
We previously reported the results of a randomized, open-label trial of egg oral immunotherapy (OIT) in 50 children where 44% were desensitized and 46% were partially desensitized after 8 months of treatment. Here we focus on cell-mediated molecular
Externí odkaz:
https://doaj.org/article/44430f4210c3418cbbc9fd4d8519f89c
Autor:
Nanna Fyhrquist, Gareth Muirhead, Stefanie Prast-Nielsen, Marine Jeanmougin, Peter Olah, Tiina Skoog, Gerome Jules-Clement, Micha Feld, Mauricio Barrientos-Somarribas, Hanna Sinkko, Ellen H. van den Bogaard, Patrick L.J.M. Zeeuwen, Gijs Rikken, Joost Schalkwijk, Hanna Niehues, Walter Däubener, Silvia Kathrin Eller, Helen Alexander, Davide Pennino, Sari Suomela, Ioannis Tessas, Emilia Lybeck, Anna M. Baran, Hamid Darban, Roopesh Singh Gangwar, Ulrich Gerstel, Katharina Jahn, Piia Karisola, Lee Yan, Britta Hansmann, Shintaro Katayama, Stephan Meller, Max Bylesjö, Philippe Hupé, Francesca Levi-Schaffer, Dario Greco, Annamari Ranki, Jens M. Schröder, Jonathan Barker, Juha Kere, Sophia Tsoka, Antti Lauerma, Vassili Soumelis, Frank O. Nestle, Bernhard Homey, Björn Andersson, Harri Alenius
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Atopic dermatitis (AD) and psoriasis (PSO) are associated with dysbiosis. Here, by analyses of skin microbiome and host transcriptome of AD and PSO patients, the authors find distinct microbial and disease-related gene transcriptomic signatures that
Externí odkaz:
https://doaj.org/article/801d353e9aec45f68391d2416fdff3f4
Autor:
Hanna-Leena Kelhälä, Riitta Palatsi, Nanna Fyhrquist, Sari Lehtimäki, Juha P Väyrynen, Matti Kallioinen, Minna E Kubin, Dario Greco, Kaisa Tasanen, Harri Alenius, Beatrice Bertino, Isabelle Carlavan, Bruno Mehul, Sophie Déret, Pascale Reiniche, Philippe Martel, Carine Marty, Ulrike Blume-Peytavi, Johannes J Voegel, Antti Lauerma
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105238 (2014)
The mechanisms of inflammation in acne are currently subject of intense investigation. This study focused on the activation of adaptive and innate immunity in clinically early visible inflamed acne lesions and was performed in two independent patient
Externí odkaz:
https://doaj.org/article/2be799c3d05146d78144b913059b859a
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107801 (2014)
Selecting relevant features is a common task in most OMICs data analysis, where the aim is to identify a small set of key features to be used as biomarkers. To this end, two alternative but equally valid methods are mainly available, namely the univa
Externí odkaz:
https://doaj.org/article/c09f792601714468969bf952927dc0cb