Isolation of cytotoxic diterpenoids from the Chilean medicinal plantAzorella compactaPhil from the Atacama Desert by high-speed counter-current chromatography

Autor: Carlos Echiburú-Chau, Gerold Jerz, Javier Vallejos, Nandy López Bartolucci, Peter Winterhalter, Mario J. Simirgiotis, Jorge Bórquez

Publikováno v: Journal of the Science of Food and Agriculture. 96:2832-2838

BACKGROUND Azorella compacta (Apiaceae) is a native Chilean cushion shrub which produces a resin containing mulinane and azorellane diterpenoids. This plant has been used since pre-Colombian times to treat inflammation and dental neuralgias. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1007108974a6f0896c30c7c40308f55f
https://doi.org/10.1002/jsfa.7451

Extracellular Trypanosoma cruzi calreticulin in the host–parasite interplay

Autor: Nandy López, Viviana P. Ferreira, Carolina Valck, Galia Ramírez, Arturo Ferreira

Publikováno v: TRENDS IN PARASITOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Calreticulin (CRT) from vertebrates is a calcium-binding protein present mainly in the endoplasmic reticulum (ER). There, it directs the conformation of proteins and controls calcium levels. This review will focus on several extracellular roles of Tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90133fd8bdc14be4b66dccc8ef1686b3
https://doi.org/10.1016/j.pt.2010.12.007

Interleukin-1β increases spinal cord wind-up activity in normal but not in monoarthritic rats

Autor: Claudio Laurido, Hernán Sáez, Teresa Pelissier, Alejandro Hernández, Mauricio Mondaca, Nandy López, Luis Constandil, Rubén Soto-Moyano, Carlos Muñoz

Publikováno v: Neuroscience Letters. 342:139-142

Cytokines produced by spinal cord glia after peripheral inflammation, infection or trauma have a relevant role in the maintenance of pain states. The effect of intrathecally administered interleukin-1beta (IL-1beta) on spinal cord nociceptive transmi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54db317b7a333863e2a88bc994ac6c6e
https://doi.org/10.1016/s0304-3940(03)00278-7

Trypanosoma cruzi calreticulin: a novel virulence factor that binds complement c1 on the parasite surface and promotes infectivity

Autor: Pedro E. Cattan, Rosario Billetta, María Carmen Molina, Carolina Valck, Wilhelm J. Schwaeble, Ismael Maldonado, Arturo Ferreira, Viviana P. Ferreira, Galia Ramírez, Gittith Sánchez, Lorena Aguilar, Carolina H. Ribeiro, Nandy López

Publikováno v: IMMUNOBIOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

In Trypanosoma cruzi, calreticulin (TcCRT) translocates from the endoplasmic reticulum (ER) to the area of flagellum emergence. We propose herein that the parasite uses this molecule to capture complement C1, in an infective apoptotic mimicry strateg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b13c5b9f1bb307202cdde22f8da3b1c

Comparative in vivo antiangiogenic effects of calreticulin from trypanosoma cruzi and homo sapiens sapiens

Autor: Carolina Valck, Ismael Maldonado, Galia Ramírez, Arturo Ferreira, Lorena Aguilar, Victor Toledo, David Lemus, Nandy López, Carolina H. Ribeiro

Publikováno v: BIOLOGICAL RESEARCH
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Biological Research, Vol 43, Iss 3, Pp 287-289 (2010)
Biological Research, Volume: 43, Issue: 3, Pages: 287-289, Published: 2010
Biological Research v.43 n.3 2010
SciELO Chile

Angiogenesis is a complex multi-step process of neovascularization arising from preexisting blood vessels whose generation is regulated by pro- and anti-angiogenic factors. Both Trypanosoma cruzi calreticulin (TcCRT) and its human counterpart (HuCRT)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f06047e4a67aad37a0327798285557c