Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nanduri Prabhakar"'
Autor:
Rengul Cetin-Atalay, Angelo Y. Meliton, David Wu, Parker S. Woods, Kaitlyn A. Sun, Ying-Jie Peng, Jayasri Nanduri, Xiaoyu Su, Yun Fang, Robert B. Hamanaka, Nanduri Prabhakar, Gökhan M. Mutlu
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Obstructive sleep apnea (OSA) is a common breathing disorder affecting a significant percentage of the adult population. OSA is an independent risk factor for cardiovascular disease (CVD); however, the underlying mechanisms are not completely underst
Externí odkaz:
https://doaj.org/article/b9c692b18c724b9f9e6edc007e2175e8
Publikováno v:
Physiology. 38
We have previously identified histone 3 (H3) post translational modifications, specifically acetylation and methylation as an early epigenetic mechanism associated with sympathetic nerve activation and hypertension in rodent models of intermittent hy
Autor:
Ying-Jie Peng, Jayasri Nanduri, Ning Wang, Vytautas Bindokas, Aaron Fox, Thibaut Vignane, Milos Filipovic, Nanduri Prabhakar
Publikováno v:
Physiology. 38
Hydrogen sulfide (H2S) is implicated in O2 sensing by the carotid body(CB) to stimulate breathing response to hypoxia. Present study shows hydrogen sulfide-dependent persulfidation (S-sulfhydration) of olfactory receptor 78 (Olfr78) as an integral co
Publikováno v:
Physiology. 38
Histone3 (H3) lysine acetylation levels regulate transcriptional activation through a dynamic process involving equilibrium between histone acetylases (KATs) and histone deacetylases (KDACs). We have previously shown that lysine acetylation of H3 is
Publikováno v:
Physiology. 38
We previously showed that activation of Olfr78 by H2S as an important component of carotid body(CB) O2 sensing. Present study delineated signaling associated with H2S/Olfr78 interaction. Odorant receptor activation is linked to olfactory G protein GO
Publikováno v:
Physiology. 38
Airway obstruction during inspiration is a hallmark trait of sleep apnea (SA). In mice, genetic elimination of the CO producing enzyme, heme oxygenase-2 (HO-2), leads to a SA phenotype predominately associated with recurrent airway obstruction. This
Autor:
Estelle B. Gauda, Maria Emilia Monteiro, Nanduri Prabhakar, Christopher Wyatt, Harold D. Schultz
This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017). Each article contains original data and represents up-to-date i
Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime
Publikováno v:
Advances in experimental medicine and biology. 860
Autor:
Jessica, Kåhlin, Souren, Mkrtchian, Anette, Ebberyd, Lalle, Hammarstedt-Nordenvall, Britt, Nordlander, Takashi, Yoshitake, Jan, Kehr, Nanduri, Prabhakar, Lorenz, Poellinger, Malin Jonsson, Fagerlund, Lars I, Eriksson
Publikováno v:
Experimental physiology. 99(8)
Studies on experimental animals established that the carotid bodies are sensory organs for detecting arterial blood O2 levels and that the ensuing chemosensory reflex is a major regulator of cardiorespiratory functions during hypoxia. However, little