Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nandita, Vishwanathan"'
Autor:
Kevin Botelho Ferreira, Asma Benlegrimet, Gabriel Diane, Victor Pasquier, Raphael Guillot, Marc De Poli, Loïc Chappuis, Nandita Vishwanathan, Jonathan Souquet, Hervé Broly, Jean‐Marc Bielser
Publikováno v:
Biotechnology progressREFERENCES. 38(4)
Implementation of continuous in lieu of batch upstream processing (USP) and downstream process (DSP) for the production of recombinant therapeutic protein is a significant paradigm change. The present report describes how the first kilograms of monoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b179f78119799f185aa5c244e4a58d
https://pubmed.ncbi.nlm.nih.gov/35412696
https://pubmed.ncbi.nlm.nih.gov/35412696
Autor:
null Kevin Botelho Ferreira, null Asma Benlegrimet, null Gabriel Diane, null Victor Pasquier, null Raphael Guillot, null Marc De Poli, null Loïc Chappuis, null Nandita Vishwanathan, null Jonathan Souquet, null Hervé Broly, null Jean‐Marc Bielser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa0c07a3f13087f41a6378c290c01d1
https://doi.org/10.1002/btpr.3259/v2/response1
https://doi.org/10.1002/btpr.3259/v2/response1
Autor:
Nandita Vishwanathan, Ziomara P. Gerdtzen, Wei Shou Hu, Nicholas J. Baltes, Alicia T. Lucero, Camila A Wilkens
Publikováno v:
Journal of Chemical Technology & Biotechnology. 94:1488-1498
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5710970a9346b614f94bf9e94a923b3e
https://doi.org/10.1002/jctb.5906
https://doi.org/10.1002/jctb.5906
Autor:
Wei Shou Hu, Hsu Yuan Fu, Sofie A. O'Brien, Nandita Vishwanathan, Liang Zhao, Arpan Bandyopadhyay
Publikováno v:
Biotechnology and Bioengineering. 116:41-53
Chinese hamster ovary cells, commonly used in the production of therapeutic proteins, are aneuploid. Their chromosomes bear structural abnormality and undergo changes in structure and number during cell proliferation. Some production cell lines are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f431fe1777991274b84077ab2f6e5a31
https://doi.org/10.1002/bit.26823
https://doi.org/10.1002/bit.26823
Autor:
Nandita Vishwanathan, Hsu Yuan Fu, Arpan Bandyopadhyay, Wei Shou Hu, Kathryn C. Johnson, Nathan M. Springer
Publikováno v:
Biotechnology and Bioengineering. 114:1903-1908
Chinese Hamster Ovary (CHO) cells are aneuploid in nature. The genome of recombinant protein producing CHO cell lines continuously undergoes changes in its structure and organization. We analyzed nine cell lines, including parental cell lines, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f2d7e36370759f92446fbd64fb4be2
https://doi.org/10.1002/bit.26311
https://doi.org/10.1002/bit.26311
Publikováno v:
Biotechnology and Bioengineering. 114:1583-1592
In the past few years, transcriptome analysis has been increasingly employed to better understand the physiology of Chinese hamster ovary (CHO) cells at a global level. As more transcriptome data accumulated, meta-analysis on data sets collected from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65fa9128d9cf3017e511a6a8ffe99aea
https://doi.org/10.1002/bit.26272
https://doi.org/10.1002/bit.26272
Autor:
Nitya M. Jacob, Mohit Sharma, Huong Le, Kevin A. T. Silverstein, Kathryn C. Johnson, George Karypis, Wei Shou Hu, Joann Mudge, Thiruvarangan Ramaraj, Hsu Yuan Fu, Nandita Vishwanathan, Getiria Onsongo, Arpan Bandyopadhyay
Publikováno v:
Biotechnology Journal. 11:1151-1157
Chinese hamster Ovary (CHO) cell lines are the dominant industrial workhorses for therapeutic recombinant protein production. The availability of genome sequence of Chinese hamster and CHO cells will spur further genome and RNA sequencing of producin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782f757f7781d4bef7cd7b592a0b58fb
https://doi.org/10.1002/biot.201500455
https://doi.org/10.1002/biot.201500455
Autor:
Arpan A, Bandyopadhyay, Sofie A, O'Brien, Liang, Zhao, Hsu-Yuan, Fu, Nandita, Vishwanathan, Wei-Shou, Hu
Publikováno v:
Biotechnology and bioengineering. 116(1)
Chinese Hamster Ovary (CHO) cells, commonly used in the production of therapeutic proteins, are aneuploid. Their chromosomes bear structural abnormality and undergo changes in structure and number during cell proliferation. Some production cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e60e8bbf11f047f366b2d529be9df9c0
https://pubmed.ncbi.nlm.nih.gov/30144379
https://pubmed.ncbi.nlm.nih.gov/30144379
Publikováno v:
Biotechnology Letters. 37:1553-1564
At the core of a biomanufacturing process for recombinant proteins is the production cell line. It influences the productivity and product quality. Its characteristics also dictate process development, as the process is optimized to complement the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcad375cb258a6f71a776eb7fe41e6ee
https://doi.org/10.1007/s10529-015-1843-z
https://doi.org/10.1007/s10529-015-1843-z
Autor:
Nandita Vishwanathan, Nitya M. Jacob, Hsu Yuan Fu, Wei Shou Hu, Huong Le, Dong-Yup Lee, Andrew Yongky, Kathryn C. Johnson, Faraaz N.K. Yusufi
Publikováno v:
Biotechnology and Bioengineering. 112:965-976
Transcriptomics is increasingly being used on Chinese hamster ovary (CHO) cells to unveil physiological insights related to their performance during production processes. The rich transcriptome data can be exploited to provide impetus for systems inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f5a63df4c639a86bec88a1069be52f6
https://doi.org/10.1002/bit.25513
https://doi.org/10.1002/bit.25513