Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nandini Pichamoorthy"'
Autor:
Eduardo E. Arteaga-Bracho, Maria Gulinello, Michael L. Winchester, Nandini Pichamoorthy, Jenna R. Petronglo, Alicia D. Zambrano, Julio Inocencio, Chirstopher D. De Jesus, Joseph O. Louie, Solen Gokhan, Mark F. Mehler, Aldrin E. Molero
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 144-155 (2016)
The mutation in huntingtin (mHtt) leads to a spectrum of impairments in the developing forebrain of Huntington's disease (HD) mouse models. Whether these developmental alterations are due to loss- or gain-of-function mechanisms and contribute to HD p
Externí odkaz:
https://doaj.org/article/033914eac2624c8087987ee040422140
Autor:
Bipasha Mukherjee, Nozomi Tomimatsu, Kaushik Amancherla, Cristel V. Camacho, Nandini Pichamoorthy, Sandeep Burma
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 1, Pp 34-43 (2012)
Inhibitors of PI3K/Akt signaling are being actively developed for tumor therapy owing to the frequent mutational activation of the PI3K-Akt-mTORC1 pathway in many cancers, including glioblastomas (GBMs). NVP-BEZ235 is a novel and potent dual PI3K/mTO
Externí odkaz:
https://doaj.org/article/3a0224af826648ffb77aacf013f8895b
Autor:
Aldrin E. Molero, Maria Gulinello, Christopher D. DeJesus, Hifza Ishtiaq, Nandini Pichamoorthy, Jenna R. Petronglo, Solen Gokhan, Mark F. Mehler, Michael L. Winchester, Eduardo E. Arteaga-Bracho, Stephen K. Young
Publikováno v:
The Journal of Neuroscience. 39:1892-1909
Emerging studies are providing compelling evidence that the pathogenesis of Huntington's disease (HD), a neurodegenerative disorder with frequent midlife onset, encompasses developmental components. Moreover, our previous studies using a hypomorphic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5a77453fe69c44b2b5d4ad68929bbd
https://doi.org/10.1523/jneurosci.2443-18.2018
https://doi.org/10.1523/jneurosci.2443-18.2018
Autor:
Kathy Y.M. Cheung, Charu Ramakrishnan, Yoon Seok Kim, Alice S. O. Hong, Nandini Pichamoorthy, Elle Yuen, Masatoshi Inoue, Maisie Lo, Sam Vesuna, Lief E. Fenno, Karl Deisseroth, Kathryn E. Evans
Publikováno v:
Neuron
Both the resolution and dimensionality with which biologists can characterize cell types have expanded dramatically in recent years, and intersectional consideration of such features (e.g. multiple gene-expression and anatomical parameters) is increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67d75947deaaeac16086902092f099f
https://europepmc.org/articles/PMC7687746/
https://europepmc.org/articles/PMC7687746/
Autor:
Solen Gokhan, Mark F. Mehler, Chirstopher D. De Jesus, Michael L. Winchester, Alicia D. Zambrano, Jenna R. Petronglo, Aldrin E. Molero, Maria Gulinello, Eduardo E. Arteaga-Bracho, Julio F. Inocencio, Joseph O. Louie, Nandini Pichamoorthy
Publikováno v:
Neurobiology of Disease, Vol 96, Iss, Pp 144-155 (2016)
The mutation in huntingtin (mHtt) leads to a spectrum of impairments in the developing forebrain of Huntington's disease (HD) mouse models. Whether these developmental alterations are due to loss- or gain-of-function mechanisms and contribute to HD p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c21c12af66d33cf9ab628350cbb5e1
http://www.sciencedirect.com/science/article/pii/S096999611630225X
http://www.sciencedirect.com/science/article/pii/S096999611630225X
Autor:
Timothy A. Machado, Isaac Kauvar, Elle Yuen, Cephra Raja, Gordon Wetzstein, John Kochalka, William E. Allen, Karl Deisseroth, Nandini Pichamoorthy
Publikováno v:
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f5c0816fef392f45ee5c9d2855d1aab
https://doi.org/10.1364/boda.2019.jw3b.2
https://doi.org/10.1364/boda.2019.jw3b.2
Autor:
Maria Gulinello, Solen Gokhan, Michael L. Winchester, Christopher H. Chen, Aldrin E. Molero, Eduardo E. Arteaga-Bracho, Mark F. Mehler, Kamran Khodakhah, Nandini Pichamoorthy
Publikováno v:
Proceedings of the National Academy of Sciences. 113:5736-5741
Recent studies have identified impairments in neural induction and in striatal and cortical neurogenesis in Huntington's disease (HD) knock-in mouse models and associated embryonic stem cell lines. However, the potential role of these developmental a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bc0d3338ed50911dbddf756b4f0853
https://doi.org/10.1073/pnas.1603871113
https://doi.org/10.1073/pnas.1603871113
Autor:
Karl Deisseroth, Christina K. Kim, Joshua H. Jennings, Li Ye, Daniel D. Tang, Nandini Pichamoorthy, Ai-Chi W. Yoo, Charu Ramakrishnan
Publikováno v:
Cell. 170(5)
Reward-seeking behavior is fundamental to survival, but suppression of this behavior can be essential as well, even for rewards of high value. In humans and rodents, the medial prefrontal cortex (mPFC) has been implicated in suppressing reward seekin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4487b638ef9848250bf0b0ab567d9e
https://pubmed.ncbi.nlm.nih.gov/28878370
https://pubmed.ncbi.nlm.nih.gov/28878370
Autor:
Soo Yeun Lee, Joshua H. Jennings, Masatoshi Inoue, Andre Berndt, Samuel Yang, Thomas J. Davidson, Charu Ramakrishnan, Karl Deisseroth, Talia N. Lerner, Nandini Pichamoorthy, Christina K. Kim, Isaac Kauvar, Noah P. Young, Haruhiko Bito
Publikováno v:
Nature methods. 13(4)
Real-time activity measurements from multiple specific cell populations and projections are likely to be important for understanding the brain as a dynamical system. Here we developed frame-projected independent-fiber photometry (FIP), which we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285d50e4a846fa8e7ef82f44880dabeb
https://pubmed.ncbi.nlm.nih.gov/26878381
https://pubmed.ncbi.nlm.nih.gov/26878381
Autor:
Kaushik Amancherla, Nandini Pichamoorthy, Sandeep Burma, Bipasha Mukherjee, Cristel V. Camacho, Nozomi Tomimatsu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 1, Pp 34-43 (2012)
ResearcherID
ResearcherID
Inhibitors of PI3K/Akt signaling are being actively developed for tumor therapy owing to the frequent mutational activation of the PI3K-Akt-mTORC1 pathway in many cancers, including glioblastomas (GBMs). NVP-BEZ235 is a novel and potent dual PI3K/mTO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5a1e1b26346881c2cfe95d2091ae10
https://doi.org/10.1593/neo.111512
https://doi.org/10.1593/neo.111512