Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Nandini Dey"'
Autor:
Raed Sulaiman, Adam Dale, Xiaoqian Lin, Jennifer C. Aske, Kris Gaster, David Starks, Luis Rojas Espaillat, Pradip De, Nandini Dey
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3441 (2024)
Lymphovascular invasion (LVSI) is defined as the presence of tumor cells within a definite endothelial-lined space (lymphatics or blood vessels) in the organ surrounding invasive carcinoma. The presence of LVI is associated with an increased risk of
Externí odkaz:
https://doaj.org/article/2d5f3e409be34675868e4e8e293e9bcd
Autor:
Raed Sulaiman, Pradip De, Jennifer C. Aske, Xiaoqian Lin, Adam Dale, Nischal Koirala, Kris Gaster, Luis Rojas Espaillat, David Starks, Nandini Dey
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11079 (2023)
The bipartite landscape of tumor cells and stromal cells determines a tumor’s response to treatment during disease management. In endometrial cancers (ECs), the mechanistic contribution of PD-L1/L2 and PD-1 signaling of the host’s tumor microenvi
Externí odkaz:
https://doaj.org/article/4440ab4ebe2b4206b8d0cf736daea14c
Autor:
Raed Sulaiman, Pradip De, Jennifer C. Aske, Xiaoqian Lin, Adam Dale, Kris Gaster, Luis Rojas Espaillat, David Starks, Nandini Dey
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1326 (2023)
The management of advanced or recurrent endometrial cancers presents a challenge due to the development of resistance to treatments. The knowledge regarding the role of the tumor microenvironment (TME) in determining the disease’s progression and t
Externí odkaz:
https://doaj.org/article/ba8f21249e95479085a329abb8dfeff8
Autor:
Raed Sulaiman, Pradip De, Jennifer C. Aske, Xiaoqian Lin, Adam Dale, Kris Gaster, Luis Rojas Espaillat, David Starks, Nandini Dey
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6449 (2023)
Cancer-associated fibroblasts (CAFs) within a solid tumor can support the progression of cancer. We studied the identification and characterization of patient-derived endometrial CAFs in the context of their clinical relevance in endometrial cancers.
Externí odkaz:
https://doaj.org/article/fb4b05b1198d4969a879bac9335737bc
Autor:
Raed Sulaiman, Pradip De, Jennifer C. Aske, Xiaoqian Lin, Adam Dale, Nischal Koirala, Kris Gaster, Luis Rojas Espaillat, David Starks, Nandini Dey
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 112 (2023)
Ovarian cancers rank first in both aggressiveness and dismal prognosis among gynecological neoplasms. The poor outcome is explained by the fact that most patients present with late-stage disease and progress through the first line of treatment. Ovari
Externí odkaz:
https://doaj.org/article/fd218910569e4b56a9bce3300ef45fca
Autor:
Raed Sulaiman, Pradip De, Jennifer C. Aske, Xiaoqian Lin, Adam Dale, Ethan Vaselaar, Cheryl Ageton, Kris Gaster, Luis Rojas Espaillat, David Starks, Nandini Dey
Publikováno v:
Cancers, Vol 14, Iss 19, p 4577 (2022)
The blood of patients with solid tumors contains circulating tumor-associated cells, including epithelial cells originating from the tumor mass, such as circulating tumor cells (CTCs), or phagocytic myeloid cells (differentiated monocytes), such as c
Externí odkaz:
https://doaj.org/article/0372a5a96e27434e9ea3e2f737d20644
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6547 (2022)
The development of HER2-targeted therapies has dramatically improved patient survival and patient management and increased the quality of life in the HER2+ breast cancer patient population. Due to the activation of compensatory pathways, patients eve
Externí odkaz:
https://doaj.org/article/38c0d7ad582f4e30878d3ac920b921c6
Autor:
Raed Sulaiman, Pradip De, Jennifer C. Aske, Xiaoqian Lin, Adam Dale, Ethan Vaselaar, Nischal Koirala, Cheryl Ageton, Kris Gaster, Joshua Plorde, Benjamin Solomon, Bradley Thaemert, Paul Meyer, Luis Rojas Espaillat, David Starks, Nandini Dey
Publikováno v:
Cancers, Vol 14, Iss 12, p 2871 (2022)
The source of circulating tumor cells (CTC) in the peripheral blood of patients with solid tumors are from primary cancer, metastatic sites, and a disseminated tumor cell pool. As 90% of cancer-related deaths are caused by metastatic progression and/
Externí odkaz:
https://doaj.org/article/d9a0b622cec546e5b653629b25f510d9
Autor:
Nandini Dey, Pradip De
Publikováno v:
Cancers, Vol 14, Iss 13, p 3202 (2022)
The future of disease management in solid tumors will rely heavily on how effectively we understand precision medicine and how successfully we can deliver personalized medicine [...]
Externí odkaz:
https://doaj.org/article/8be71318823e48a0810261f1fc06052a
Publikováno v:
Cancers, Vol 14, Iss 6, p 1519 (2022)
In tumor cells’ struggle for survival following therapy, they resist treatment. Resistance to therapy is the outcome of well-planned, highly efficient adaptive strategies initiated and utilized by these transformed tumor cells. Cancer cells undergo
Externí odkaz:
https://doaj.org/article/dcb14b733ac6424a89403169e067aa5c