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pro vyhledávání: '"Nandini Banik"'
Autor:
Donald J. Kyle, Yakov Rotshteyn, E. A. M. Seeds, Clive P. Page, Gary Douglas, Perry V. Halushka, Mark Chasin, Donna Donigi Gale, Tatsui Matsumoto, David Cavalla, Ronald M. Burch, Katherine H Banner, Nandini Banik, Domenico Spina, Forrest L. Smith, Richard H. Wong, Selina Harrison, Peter Hofer, Stephan Jordan
Publikováno v:
Pulmonary pharmacologytherapeutics. 16(2)
V11294 is a new cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor of the rolipram class. In this report we present the pharmacological profile of V11294. V11294 inhibited PDE4 isolated from human lung with IC 50 405 nM, compared to 3700 nM