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pro vyhledávání: '"Nandidni N. Kishore"'
Autor:
Sharon Rouw, Adam Libby, Michael Clare, Horng-Chih Huang, Cynthia D. Sommers, Julia A. Guzova, Nandidni N. Kishore, Richard Weier, Sheri L. Bonar, Sumathy Mathialagan, Lori J. Vanella, Dominique Bonafoux, Jeanette L. Glaenzer, Koszyk Francis, Ann M. Donnelly, He Huang, David S. Oburn, Patrick J. Lennon, Catherine S. Tripp, Serge G. Wolfson
Publikováno v:
Bioorganicmedicinal chemistry. 18(1)
Series of aminopyridinecarboxamide-based inhibitors were synthesized and tested against human recombinant IKK-2 and in IL-1beta stimulated synovial fibroblasts. The 2-amino-5-chloropyridine-4-carboxamides were identified as the most potent inhibitors