Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Nandadeva, Lokugamage"'
Autor:
Lizette Elaine Rios, Nandadeva Lokugamage, Subhadip Choudhuri, Imran Hussain Chowdhury, Nisha Jain Garg
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract This study investigated a candidate vaccine effect against maternal Trypanosoma cruzi (Tc) infection and improved pregnancy outcomes. For this, TcG2 and TcG4 were cloned in a nanoplasmid optimized for delivery, antigen expression, and regula
Externí odkaz:
https://doaj.org/article/da8a948a474542299f999812a3b2f2f7
Autor:
Nandadeva Lokugamage, Imran H. Chowdhury, Ronald J. Biediger, Robert V. Market, Sayadeth Khounlo, Navin D. Warier, Shen-An Hwang, Jeffrey K. Actor, Darren G. Woodside, Upendra Marathi, Peter Vanderslice, Nisha Jain Garg
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract The development of suitable safe adjuvants to enhance appropriate antigen-driven immune responses remains a challenge. Here we describe the adjuvant properties of a small molecule activator of the integrins αLβ2 and α4β1, named 7HP349, w
Externí odkaz:
https://doaj.org/article/fa56993f549b4cbda0b8eb8236c01b18
Publikováno v:
The American Journal of Pathology. 193:313-331
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A parasitic protozoan Trypanosoma cruzi (T. cruzi) is the etiologic agent of Chagas disease. Previously, we have identified T. cruzi antigens TcG2 and TcG4 as potential vaccine candidates, cloned in eukaryotic expression vector pCDNA3.1 (referred as
Externí odkaz:
https://doaj.org/article/19152b1d08fa41c281c2356ed198968b
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007904 (2019)
Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to Africa and the Middle East, affecting both humans and ruminants. There are no licensed vaccines or antivirals available for humans, whereas research using RVF virus (RVFV) is str
Externí odkaz:
https://doaj.org/article/fb4d0ba123e348e98ac4a0ca4dccbae0
Autor:
Nandadeva Lokugamage, Tetsuro Ikegami
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-10 (2017)
Rift Valley fever: Whole-virus vaccine alters the attenuation profile A vaccine candidate for Rift Valley fever virus can undergo mutations and partially revert to parental pathogenic strain. Rift Valley fever is a prolific infection that affects liv
Externí odkaz:
https://doaj.org/article/6877a549b3d44f31b2c263a6a429ad79
Autor:
Shivali Gupta, Berenice Salgado-Jiménez, Nandadeva Lokugamage, Juan Carlos Vázquez-Chagoyán, Nisha Jain Garg
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Chagas cardiomyopathy is caused by Trypanosoma cruzi (Tc). Two antigenic candidates, TcG2 and TcG4, are recognized by antibodies in naturally infected dogs and humans; and these vaccine candidates provided protection from Tc infection in
Externí odkaz:
https://doaj.org/article/c455e81e63cb4a1887fb49f3c8204497
Autor:
Nandadeva Lokugamage, Subhadip Choudhuri, Carolina Davies, Imran Hussain Chowdhury, Nisha Jain Garg
Publikováno v:
Vaccines, Vol 8, Iss 1, p 96 (2020)
Chagas cardiomyopathy is caused by Trypanosoma cruzi (Tc). We identified two candidate antigens (TcG2 and TcG4) that elicit antibodies and T cell responses in naturally infected diverse hosts. In this study, we cloned TcG2 and TcG4 in a nanovector an
Externí odkaz:
https://doaj.org/article/cea0a5a99f0a4018ae138eeb1e32c351
Autor:
Imran H. Chowdhury, Marathi Upendra K, Peter Vanderslice, Nisha Jain Garg, Jeffrey K. Actor, Nandadeva Lokugamage, Shen-An Hwang, Biediger Ronald J, Market Robert, Navin D. Warier, Darren G. Woodside, Sayadeth Khounlo
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
NPJ Vaccines
NPJ Vaccines
The development of suitable safe adjuvants to enhance appropriate antigen-driven immune responses remains a challenge. Here we describe the adjuvant properties of a small molecule activator of the integrins αLβ2 and α4β1, named 7HP349, which can
Autor:
Tetsuro Ikegami, Aaron Balogh, Shoko Nishiyama, Nandadeva Lokugamage, Tais B Saito, John C Morrill, Vinay Shivanna, Sabarish V Indran, Lihong Zhang, Jennifer K Smith, David Perez, Terry L Juelich, Igor Morozov, William C Wilson, Alexander N Freiberg, Juergen A Richt
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189250 (2017)
Rift Valley fever phlebovirus (RVFV) causes high rates of abortions and fetal malformations in ruminants, and hemorrhagic fever, encephalitis, or blindness in humans. Viral transmission occurs via mosquito vectors in endemic areas, which necessitates
Externí odkaz:
https://doaj.org/article/97d0de26605c4e4f90aca0a0d6adc0b0