Výsledky vyhledávání - "Nanda K Nayuni"

The differences between the branded and generic medicines using solid dosage forms: In-vitro dissolution testing

Autor: Atholl Johnston, Mubarak Nasser Al Ameri, David Perrett, Arthur Tucker, K.G. Anil Kumar, Nanda K Nayuni

Publikováno v: Results in Pharma Sciences. 2:1-8

IntroductionDissolution is the amount of substance that goes into solution per unit time under standardised conditions of liquid/solid interface, solvent composition and temperature. Dissolution is one of the most important tools to predict the in-vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff8541ea18bea8ae437ee1548c710c3

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Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia

Autor: Julius Kieswich, Martin Raftery, Jonathan R. Seckl, Nanda K Nayuni, Steven Harwood, Petros Andrikopoulos, Roger Corder, Christoph Thiemermann, Brian R. Walker, Muhammad M. Yaqoob, Ananda Chapagain, Scott P. Webster, Paul W. Caton, Jamie H. Long

Insulin resistance and associated metabolic sequelae are common in chronic kidney disease (CKD) and are positively and independently associated with increased cardiovascular mortality. However, the pathogenesis has yet to be fully elucidated. 11β-Hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fc6f071a291943e41ed390bac092d9
https://europepmc.org/articles/PMC3956172/

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Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism

Autor: Roger Corder, Elizabeth G. Wood, Nanda K Nayuni, Paul W. Caton, Noorafza Q. Khan

Publikováno v: The Journal of endocrinology. 208(3)

Consumption of a fructose-rich diet leads to insulin resistance and dyslipidemia in part due to elevated gluconeogenesis and lipogenesis. SIRT1, an NAD(+)-dependent protein deacetylase, can induce gluconeogenesis and lipogenesis. The aim of this stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f53cac0c2f0801f4742168c82c3e058
https://pubmed.ncbi.nlm.nih.gov/21212096

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Endotoxin induced hyperlactatemia and hypoglycemia is linked to decreased mitochondrial phosphoenolpyruvate carboxykinase

Autor: Roger Corder, Oliver Murch, Paul W. Caton, Nanda K Nayuni

Publikováno v: Life sciences. 84(21-22)

Aims Phosphoenolpyruvate carboxykinase (PEPCK) is the rate limiting enzyme for gluconeogenesis, and plays a key role in recycling lactate for glucose production. It is synthesized as two separate isoforms; cytosolic (PEPCK-C, gene code; PCK1) and mit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e4b0cfbe831209fc80bac2ba6461ec
https://pubmed.ncbi.nlm.nih.gov/19268478

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