Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nand K. Gaur"'
Autor:
Douglas F. Lake, Y. Park, Peter N. Lipke, Nand K. Gaur, K. S. Hahm, Stephen A. Klotz, Jason M. Rauceo
Publikováno v:
Antimicrobial agents and chemotherapy. 64(8)
Candida albicans adheres to host tissue and then proliferates in order to establish a commensal as well as a pathogenic state. Specific adherence to proteins is provided by several surface adhesins of Candida. Two well-studied proteins, Als1p and Als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1256bef9e8644bb97a48d4a09da5c24e
https://pubmed.ncbi.nlm.nih.gov/15504862
https://pubmed.ncbi.nlm.nih.gov/15504862
Autor:
Aaron T. Frank, Cho Tan, Jason M. Rauceo, Peter N. Lipke, Stephen A. Klotz, Gregory Soybelman, Caleen B. Ramsook, Henry N. Otoo, Nand K. Gaur
Publikováno v:
Eukaryotic Cell. 9:405-414
Tandem repeat (TR) regions are common in yeast adhesins, but their structures are unknown, and their activities are poorly understood. TR regions in Candida albicans Als proteins are conserved glycosylated 36-residue sequences with cell-cell aggregat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1559e653fb1e0d656d83c45925496da
https://doi.org/10.1128/ec.00235-09
https://doi.org/10.1128/ec.00235-09
Autor:
Peter N. Lipke, Stephen A. Klotz, Richard E. Sobonya, Kevin B. Gilchrist, Jennifer Thorn, Nand K. Gaur
Publikováno v:
Journal of Clinical Pathology. 63:337-340
AimThe significance of finding Candida species in heart blood cultures obtained at postmortem examination has never been studied. This article describes the findings of autopsy patients with postmortem candidaemia and it compares them with findings i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358215945a55e3f3c4032fad6fc61c97
https://doi.org/10.1136/jcp.2009.070607
https://doi.org/10.1136/jcp.2009.070607
Autor:
Peter N. Lipke, Yves F. Dufrêne, Stephen A. Klotz, David Alsteens, Vincent Dupres, Nand K. Gaur
Publikováno v:
ACS Nano. 3:1677-1682
Elucidating the molecular mechanisms behind the strength and mechanics of cell adhesion proteins is of central importance in cell biology and offers exciting avenues for the identification of potential drug targets. Here we use single-molecule force
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cf636281fbfc4c36b6388d1ca61e13
https://doi.org/10.1021/nn900078p
https://doi.org/10.1021/nn900078p
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 59:401-406
Candida species are the 4th most common cause of nosocomial bloodstream infections in North America. It is not widely appreciated, however, that many of these infections are polymicrobial, that is, that bacteria and occasionally more than 1 species o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ab7e73d65ce00ba1290ded5ec4039a
https://doi.org/10.1016/j.diagmicrobio.2007.07.001
https://doi.org/10.1016/j.diagmicrobio.2007.07.001
Autor:
Jason M. Rauceo, Richard De Armond, Peter C. Kahn, Nand K. Gaur, Peter N. Lipke, Stephen A. Klotz, Henry N. Otoo
Publikováno v:
Eukaryotic Cell. 5:1664-1673
Commensal and pathogenic states of Candida albicans depend on cell surface-expressed adhesins, including those of the Als family. Mature Als proteins consist of a 300-residue N-terminal region predicted to have an immunoglobulin (Ig)-like fold, a 104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1893cedecf27d6dca8132ceb043bb7
https://doi.org/10.1128/ec.00120-06
https://doi.org/10.1128/ec.00120-06
Autor:
Kyeng Gea Lee, John E. Edwards, Nand K. Gaur, Stephen A. Klotz, Peter N. Lipke, Jason M. Rauceo
Publikováno v:
Infection and Immunity. 72:4948-4955
Candida albicans maintains both commensal and pathogenic states in humans. Both states are dependent on cell surface-expressed adhesins, including those of the Als family. Heterologous expression of Als5p at the surface of Saccharomyces cerevisiae re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06183ad00a64017ab8d72233497d0743
https://doi.org/10.1128/iai.72.9.4948-4955.2004
https://doi.org/10.1128/iai.72.9.4948-4955.2004
Autor:
Stephen A. Klotz, Nand K. Gaur
Publikováno v:
Microbiology. 150:277-284
Candida albicans displays a high degree of specificity in selecting and adhering to targets in vivo. The features of target recognition are poorly understood and likely to involve more than the mere chemical composition of the ligand. Using an adhere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d318e9792840772e0800933c8147d6
https://doi.org/10.1099/mic.0.26738-0
https://doi.org/10.1099/mic.0.26738-0
Publikováno v:
Cell Communication & Adhesion. 9:45-57
Saccharomyces cerevisiae transformed with Candida albicans ALA1/ALS5 exhibits adherence properties similar to C. albicans. Adherence of the fungi to immobilized proteins involves hydrogen bonds, is stable to shear forces, and is resistant to competit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b2b2c88fba36ae14886ca3c6e4523a
https://doi.org/10.1080/15419060212187
https://doi.org/10.1080/15419060212187
Publikováno v:
Infection and Immunity. 67:6040-6047
Candida albicans maintains a commensal relationship with human hosts, probably by adhering to mucosal tissue in a variety of physiological conditions. We show that adherence due to the C. albicans gene ALA1 when transformed into Saccharomyces cerevis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dee7412bcc4702d9550564411a09f09b
https://doi.org/10.1128/iai.67.11.6040-6047.1999
https://doi.org/10.1128/iai.67.11.6040-6047.1999