Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nand Baindur"'
Autor:
Carl L. Manthey, Nand Baindur, Ioanna Petrounia, Celine Schalk-Hihi, Naresh Chadha, Christian Andrew Baumann, Heidi Ott, Benjamin M. Brandt, Raymond J. Patch, Mark R. Player, Davoud Asgari, Barry A. Springer, Theodore E. Carver
Publikováno v:
Journal of Medicinal Chemistry. 48:1717-1720
2-Hydroxy-4,6-diamino-[1,3,5]triazines are described which are a novel class of potent inhibitors of the VEGF-R2 (flk-1/KDR) tyrosine kinase. 4-(Benzothiazol-6-ylamino)-6-(benzyl-isopropyl-amino)-[1,3,5]triazin-2-ol (14d) exhibited low nanomolar pote
Publikováno v:
Journal of Combinatorial Chemistry. 5:653-659
An efficient solution-phase parallel synthesis of a library of 3,5,7-trisubstituted [1,2,3]triazolo[4,5-d]pyrimidines is described. Monosubstituted amidines may be converted to 2-substituted 5-amino-4,6-dihydroxypyrimidines in four steps. Treatment w
Autor:
Nand Baindur, Margery A. Chaikin, Davoud Asgari, Wing S. Cheung, Ioanna Petrounia, Robert R. Donatelli, Taxiarchis Georgiadis, Naresh Chadha, Raymond J. Patch, Mark R. Player, Benjamin M. Brandt
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(22)
A series of 2′-aminoanilides have been identified which exhibit potent and selective inhibitory activity against the cFMS tyrosine kinase. Initial SAR studies within this series are described which examine aroyl and amino group substitutions, as we
Publikováno v:
Journal of combinatorial chemistry. 6(2)
Monoamides of oxalic acid are of interest as bioisosteric replacements for phosphate groups in the design of new enzyme inhibitors. Here, we have demonstrated the use of oxalic acid as a linker to the Wang resin to synthesize individual or libraries
Publikováno v:
ChemInform. 35
Autor:
Nand Baindur, Celine Schalk-Hihi, Matthew Wayne Olson, Keli C. Dzordzorme, Ruth Steele, Jennifer Kirkpatrick, Kenneth R. Singleton, Marina I. Nelen, Min Xiang, Lawrence Kuo, James Lenhard, Mike Gaul, Gee Hong Kuo, Christian Andrew Baumann, Todd J. Matthew, Wenfeng Sun, Erica L Nulton
Publikováno v:
The FASEB Journal. 22:332-332