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of 5
pro vyhledávání: '"Nancy Winslow"'
Publikováno v:
Translational Research. 149:333-342
Maleimide-polyethylene glycol-modified (MalPEG) hemoglobin, 4.3 g/dL (MP4; Hemospan), is a hemoglobin-based oxygen carrier consisting of human hemoglobin (Hb) modified with maleimide polyethylene glycol. This study evaluates the potential toxicity an
Autor:
Per Nellgård, Robert J. Przybelski, Robert M. Winslow, Christina Olofsson, Nancy Winslow, Sari Ponzer, Torsten Johansson, Peter Keipert, Torbjörn Ahl, Bengt Fagrell, Sune Larsson
Publikováno v:
Anesthesiology. 105:1153-1163
Background Hemospan (Sangart Inc., San Diego, CA), a polyethylene glycol-modified hemoglobin with unique oxygen transport properties, has successfully completed a phase I trial in healthy volunteers. Because adverse events are expected to increase wi
Autor:
Magnus, Björkholm, Bengt, Fagrell, Robert, Przybelski, Nancy, Winslow, Mark, Young, Robert M, Winslow
Publikováno v:
Haematologica. 90(4)
MP4 (Hemospan), a hemoglobin-based oxygen carrier, has been designed to deliver oxygen to hypoxic tissues without causing vasoconstriction. A phase I clinical trial of MP4 was undertaken to evaluate whether MP4 elicits the clinical side effects assoc
Autor:
Robert J. Przybelski, Bengt Fagrell, Nancy Winslow, Per Nellgård, Sune Larsson, Torbjörn Ahl, Peter Keipert, Nina Olofsson, Robert M. Winslow, Sari Ponzer, Torsten Johansson
Publikováno v:
Critical Care Medicine. 33:A6
Publikováno v:
Respiration physiology. 61(2)
Measurements of whole blood O2 affinity were made with an automatic technique that allowed recording of O2 saturation continuously over a range of PO2 of 1 to 150 torr at constant pH and PCO2 with fresh samples of blood obtained from 5 natives of hig