Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nancy Vander Heyden"'
Publikováno v:
Journal of Virology. 77:13389-13395
Alpha-2a interferon (IFN-α2a) has beneficial clinical effects on human T-cell leukemia virus type 1 (HTLV-1) infection, but its antiviral mechanism of action is unknown. Antiviral effects of IFN-α2a were studied in 293T cells expressing HTLV-1 prov
Autor:
Lee Ratner, Nancy Vander Heyden
Publikováno v:
AIDS Research and Human Retroviruses. 9:291-297
The effects on HIV-1 infection of a glucosidase inhibitor, N-butyl deoxynojirimycin (N-buDNJ), were examined. The combinations of N-buDNJ and nucleoside analogs dideoxyinosine (DDI), dideoxycytidine (DDC), or azidothymidine (AZT) were examined in an
Autor:
Michael Becich, Michael Polinsky, Peter Westervelt, Lee Ratner, Juan Carlos Garcia, Nancy Vander Heyden
Publikováno v:
AIDS Research and Human Retroviruses. 7:287-294
Deletions were constructed within a functional human immunodeficiency virus type 1 (HIV-1) proviral clone in order to assess the role of the envelope protein in virus particle formation. A graded exonuclease deletion technique was used to produce 12
Publikováno v:
Virology. 181:180-192
Processing of HIV and SIV envelope oligosaccharides is critical for proper intracellular trafficking and function. An inhibitor of α-glucosidases I and 11, N -butyl deoxynojirimycin ( N -BuDNJ), retards HIV-1 and SIVmac spread in lymphocytes and mon
Autor:
Michael Dale Lairmore, Nancy Vander Heyden, Elizabeth Paine, Debra Frei-Lahr, Randy G. Brown, Satyanarayan Reddy, Paul J. Petruska, Lee Ratner
Publikováno v:
American Journal of Hematology. 34:215-222
Clinical and laboratory data are described for two siblings who both developed adult T-cell leukemia/lymphoma resulting from infection by human T lymphotropic virus type I (HTLV-I). These findings suggest that genetic factors or virus-specific factor
Publikováno v:
Journal of virology. 74(13)
Vpx is a virion-associated protein of human immunodeficiency virus type 2 (HIV-2) and simian immunodeficiency viruses. The yeast two-hybrid system was used to identify invariant chain (Ii) as a cellular protein that interacts with HIV-2 Vpx. Vpx-Ii i
Publikováno v:
Journal of virological methods. 85(1-2)
Phenotypic drug susceptibility assays of human immunodeficiency virus type 1 (HIV-1) isolates generally use time-consuming, expensive assays with peripheral blood mononuclear cells. A new HIV-1 indicator cell line, MAGI-CCR5, has been developed and a
Publikováno v:
Nature medicine. 5(1)
At present, treatment of HIV infection uses small inhibitory molecules that target HIV protease; however, the emergence of resistant HIV strains is increasingly problematic. To circumvent this, we report here a new 'Trojan horse' strategy to kill HIV
Autor:
Francis Chiu, Nancy Vander Heyden, Jeremy Green, George Glover, Lee Ratner, Mihaly V. Toth, Stephen B. H. Kent, Daniel H. Rich, Garland R. Marshall
Publikováno v:
Peptides ISBN: 9789401090629
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bef3a0f9d5b7e88135c6fd62323df50
https://doi.org/10.1007/978-94-010-9060-5_280
https://doi.org/10.1007/978-94-010-9060-5_280
Publikováno v:
AIDS Research and Human Retroviruses. 5:647-653
Several different nucleoside analogs have been demonstrated to inhibit retroviral RNA-dependent DNA polymerase activity in preference to cellular DNA-dependent DNA polymerases. 3'-Amino derivatives of 3-deoxyadenosine was analyzed for their antiviral