Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nancy V. Brown"'
Autor:
John Sidney, Tonia Woodberry, Nicole Frahm, Kaori Sango, Simon Mallal, Eunice Pae, Florian Bihl, Carl M. Kadie, Nebojsa Jojic, Bruce D. Walker, Karina Yusim, Todd J. Suscovich, Alessandro Sette, Peter T. Hraber, Kellie Faircloth, Ashok Khatri, Francesco M. Marincola, Sharon Adams, Daniel G. Kavanagh, Hannah S. Hewitt, Caitlyn Linde, Jennifer Listgarten, Mina John, Christian Brander, Leah M. Henry, M. Tauheed Zaman, Bette T. Korber, Nancy V. Brown, David Heckerman
Publikováno v:
European Journal of Immunology. 37:2419-2433
Promiscuous binding of T helper epitopes to MHC class II molecules has been well established, but few examples of promiscuous class I-restricted epitopes exist. To address the extent of promiscuity of HLA class I peptides, responses to 242 well-defin
Autor:
Simon Delagrave, Thomas P. Monath, B. Barrere, Zhenxi Zhang, Konstantin V. Pugachev, S. Cyrek, I. Levenbook, Nancy V. Brown, C. Fournier, Barbara W. Johnson, Jean Lang, Farshad Guirakhoo, Ken Draper, Richard A. Nichols, Gwendolyn A. Myers
Publikováno v:
Journal of Virology. 78:9998-10008
A chimeric yellow fever-dengue 1 (ChimeriVax-DEN1) virus was produced by the transfection of Vero cells with chimeric in vitro RNA transcripts. The cell culture supernatant was subjected to plaque purification for the identification of a vaccine cand
Autor:
Ashok Khatri, James I. Mullins, P. Adolf, James J. Szinger, T. Simonis, David Stone, Devi SenGupta, Bruce D. Walker, Christian Brander, K. Davis, Alicja Piechocka-Trocha, C. M. Adams, Daniel E. Cohen, Alysse G. Wurcel, Karina Yusim, Philip J. R. Goulder, Bette T. Korber, Nancy V. Brown, Timothy Roach, A. StJohn, F. M. Marincola, Rika Draenert, Kaori Sango, Nicole Frahm, Christopher J. Russell, Marylyn M. Addo, Margaret E. Feeney
Publikováno v:
Journal of Virology. 78:2187-2200
Although there is increasing evidence that virus-specific cytotoxic-T-lymphocyte (CTL) responses play an important role in the control of human immunodeficiency virus (HIV) replication in vivo, only scarce CTL data are available for the ethnic popula
Autor:
Andrew D. Luster, Hungyi Shau, Marylyn M. Addo, Ralf Geiben-Lynn, Mischo Kursar, Judy Lieberman, Bruce D. Walker, Nancy V. Brown
Publikováno v:
Journal of Biological Chemistry. 278:1569-1574
CD8(+) T-cells are a major source for the production of non-cytolytic factors that inhibit HIV-1 replication. In order to characterize further these factors, we analyzed gene expression profiles of activated CD8(+) T-cells using a human cDNA expressi
Publikováno v:
Journal of Biological Chemistry. 277:42352-42357
CD8(+) T-cells secrete soluble factor(s) capable of inhibiting both R5- and X4-tropic strains of human immunodeficiency virus type 1 (HIV-1). CCR5 chemokine ligands, released from activated CD8(+) T-cells, contribute to the antiviral activity of thes
Publikováno v:
Alcoholism: Clinical and Experimental Research. 24:716-726
Background: Ethanol inhibition of insulin signaling pathways may contribute to impaired central nervous system (CNS) development in the fetal alcohol syndrome and brain atrophy associated with alcoholic neurodegeneration. Previous studies demonstrate
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:770-777
Insulin stimulation increases cell proliferation and energy metabolism by activating the insulin receptor substrate I (IRS-1)-signaling pathways. This downstream signaling is mediated by interactions of specific tyrosyl phosphorylated (PY) IRS- motif
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 55:1038-1050
Neuronal thread proteins (NTPs) comprise a family of molecules expressed in brain and primitive neuroectodermal tumor cell lines. In Alzheimer's disease (AD), increased CNS levels of the 21 kD NTP species are correlated with dementia. The present stu
Autor:
Fritz von Weizsäcker, Eiki Maeda, Terukatsu Arima, Jean-Claude Caput, Thierry Poynard, Siegfried Labeit, Jack R. Wands, Hubert E. Blum, Nancy V. Brown, Eithan Galun
Publikováno v:
Scopus-Elsevier
The presence of low level hepatitis B virus (HBV) and hepatitis C virus (HCV) infections was assessed in serum from 67 hepatitis B surface antigen (HBsAg) negative alcoholics from France without previous blood transfusions and/or i.v. drug abuse. It
Publikováno v:
Alcoholism: Clinical and Experimental Research. 19:441-446
Ethanol inhibits insulin (IN) and epidermal growth factor (EGF)-induced hepatocyte DNA synthesis. Growth factor receptor kinases, such as IN and EGF, phosphorylate insulin receptor substrate (IRS-1) and p36 protein kinase substrate, respectively, on