Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Nancy Troiano"'
Publikováno v:
J Am Soc Nephrol
Background We recently showed the transcription factor Early B cell factor 1 (EBF1) is essential for the last stages of metanephric development, and that mice globally deficient in EBF1 display impaired maturation of peripheral glomeruli. EBF1 is pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f744b0f4a5ef4c39ce29678fa002d90b
https://doi.org/10.1681/asn.2018070699
https://doi.org/10.1681/asn.2018070699
Autor:
Ben-hua Sun, João Pereira, Katarzyna Saar, Meiling Zhu, LeAnn M. Tiede-Lewis, Robert S. Weinstein, Nancy Troiano, Sarah L. Dallas, Erin Nevius, Steven M. Tommasini, Karl L. Insogna, Christine A. Simpson
Publikováno v:
Journal of Bone and Mineral Research. 31:864-873
Rac1 and Rac2 are thought to have important roles in osteoclasts. Therefore, mice with deletion of both Rac1 and Rac2 in mature osteoclasts (DKO) were generated by crossing Rac1(flox/flox) mice with mice expressing Cre in the cathepsin K locus and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0e04094870baee677ffba462f8f4646
https://doi.org/10.1002/jbmr.2733
https://doi.org/10.1002/jbmr.2733
Autor:
Arijeet K. Gattu, Thomas O. Carpenter, Matthew S. Rodeheffer, Ryan Berry, E. Scott Swenson, Yasuko Iwakiri, Varman T. Samuel, Chuhan Chung, Nancy Troiano, Christopher D. Church
Publikováno v:
The FASEB Journal. 27:4384-4394
Pigment epithelium-derived factor (PEDF), the protein product of the SERPINF1 gene, has been linked to distinct diseases involving adipose or bone tissue, the metabolic syndrome, and osteogenesis imperfecta (OI) type VI. Since mesenchymal stem cell (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e405daea90fe3eaa11a1927479a1ca0
https://doi.org/10.1096/fj.13-232900
https://doi.org/10.1096/fj.13-232900
Publikováno v:
Journal of Bone and Mineral Metabolism. 30:408-418
To better define the biologic function of membrane-bound CSF1 (mCSF1) in vivo, we have generated mCSF1 knockout (k/o) mice. Spinal bone density (BMD) was 15.9% higher in k/o mice compared to wild-type (wt) controls (P < 0.01) and total BMD was increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c36e684cac418fa7235986087c1db9
https://doi.org/10.1007/s00774-011-0336-y
https://doi.org/10.1007/s00774-011-0336-y
Publikováno v:
Journal of Bone and Mineral Metabolism. 29:141-148
Parathyroid hormone (PTH) is a potent ana- bolic agent, but the cellular mechanisms by which it increases bone mass are not fully understood. Dickkopf 1 (Dkk1) is an endogenous inhibitor of Wnt signaling and suppresses bone formation in vivo. We soug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b096cd8ec0cce5ba7673a5cb6dfb21
https://doi.org/10.1007/s00774-010-0202-3
https://doi.org/10.1007/s00774-010-0202-3
Autor:
Catherine A. Brownstein, Richard P. Lifton, Caren M. Gundberg, Nancy Troiano, Douglas J. Adams, Thomas O. Carpenter, Junhui Zhang, Bruce Ellis, Althea A. Stillman
Publikováno v:
Endocrinology. 151:492-501
Inactivating mutations of PHEX cause X-linked hypophosphatemia and result in increased circulating fibroblast growth factor 23 (FGF23). FGF23 action is dependent upon Klotho, which converts FGF receptor 1 into an FGF23-specific receptor. Disruption o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77caa116a17dfea354afbf8982a56f14
https://doi.org/10.1210/en.2009-0564
https://doi.org/10.1210/en.2009-0564
Autor:
Yukiji K. Fujimoto, Adele L. Boskey, Lyudmila Spevak, Kostas Verdelis, William M. Philbrick, Nancy Troiano, Bruce Ellis, Thomas O. Carpenter, Aaron T. Frank
Publikováno v:
Calcified Tissue International. 84:126-137
Hypophosphatemia is an X-linked dominant disorder resulting from a mutation in the PHEX gene. While osteoblast-specific expression of the PHEX transgene has been reported to decrease the phosphate wasting associated with the disease in male hypophosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f3f846d83233437afab174cb18dc2b
https://doi.org/10.1007/s00223-008-9201-y
https://doi.org/10.1007/s00223-008-9201-y
Publikováno v:
Journal of Histotechnology. 31:169-173
Alkaline phosphatase and acid phosphatase are two major enzymatic measures of osteoblastic and osteoclastic activity, respectively. As a result, the preservation of the enzymes in bone specimens to near in vivo accuracy is essential. Despite standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37a53017fb969c840319fc1f4bf84ed
https://doi.org/10.1179/his.2008.31.4.169
https://doi.org/10.1179/his.2008.31.4.169
Publikováno v:
Journal of Histotechnology. 31:61-64
Pamela Dannl, Julie R. Hensl, Nancy W. Troiano2, John J. Wysolmerskil, and Melissa A. Kacena2,3*I Department of Internal Medicine, Yale University School of Medicitte, New Haven, CT2 Department of Orthopaedics and Rehabilitation, Yale University Scho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ac4e8c5fb24804e5e07895ae6bc3dcf
https://doi.org/10.1179/his.2008.31.2.61
https://doi.org/10.1179/his.2008.31.2.61
Autor:
Melissa A. Kacena, Christiane E. Coady, Nancy Troiano, Christopher K. Breuer, Reynold I. Lopz-Soler, Jason D. Roh
Publikováno v:
Journal of Histotechnology. 29:245-250
The use of autologous arteries or veins is the “gold standard” for cardiovascular bypass grafting to repair congenital defects or diseased vessels. Nonetheless, a limited supply of healthy vessels for harvest necessitates the use of alternative g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3b0a594ae2662682da37c6fa74ab870
https://doi.org/10.1179/his.2006.29.4.245
https://doi.org/10.1179/his.2006.29.4.245