Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nancy T, Sklarin"'
Autor:
Shanu Modi, Sarat Chandarlapaty, Nancy T. Sklarin, Monica N. Fornier, Neal Rosen, Sujata Patil, Alexia Iasonos, Fanni Ratzon, Fresia Pareja, Rui Wang, Payal Deepak Shah, Joshua Z. Drago, Komal Jhaveri
Purpose:Activating mutations in PIK3CA promote resistance to HER2-targeted therapy in breast cancer; however, inhibition of PI3K alone leads to escape via feedback upregulation of HER3. Combined inhibition of HER2, HER3, and PI3K overcomes this mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ae01f97661fac0629fd8d398512a0d
https://doi.org/10.1158/1078-0432.c.6530615
https://doi.org/10.1158/1078-0432.c.6530615
Autor:
Komal, Jhaveri, Joshua Z, Drago, Payal Deepak, Shah, Rui, Wang, Fresia, Pareja, Fanni, Ratzon, Alexia, Iasonos, Sujata, Patil, Neal, Rosen, Monica N, Fornier, Nancy T, Sklarin, Sarat, Chandarlapaty, Shanu, Modi
Publikováno v:
Clin Cancer Res
BACKGROUND: Activating mutations in PIK3CA promote resistance to HER2-targeted therapy in breast cancer, however inhibition of PI3K alone leads to escape via feedback upregulation of HER3. Combined inhibition of HER2, HER3 and PI3K overcomes this mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89eeec9e8a106422ff5b1077e16fd370
https://pubmed.ncbi.nlm.nih.gov/33947692
https://pubmed.ncbi.nlm.nih.gov/33947692
Autor:
Sylvia Thomas, Williamn R. Grove, Laura Benson, Chetan D. Lathia, Nancy T. Sklarin, Avi I. Einzig, Javier Roca, Peter H. Wiernik
Publikováno v:
Investigational New Drugs. 15:235-246
CI-980 is a synthetic mitotic inhibitor that binds to the colchicine binding site of tubulin. It demonstrates broad activity against human and murine tumor models and shows no cross resistance with tumor models whose mechanism of resistance is mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160ac4c6bb3bf5e831456b18370cecb8
https://doi.org/10.1023/a:1005854510468
https://doi.org/10.1023/a:1005854510468
Autor:
Peter H. Wiernik, Joseph A. Sparano, Edward S. Greenwald, Nancy T. Sklarin, Janice P. Dutcher
Publikováno v:
Medical Oncology. 11:121-125
Women diagnosed with primary breast or lung cancer and recorded between 1972 and 1989 in our tumor registry were identified. Of 4,123 lung cancer patients and 3,537 breast cancer patients, 42 patients with both diagnoses were identified. The two mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745ef570f2905ae7ff3a953cd0a4c107
https://doi.org/10.1007/bf02999859
https://doi.org/10.1007/bf02999859
Implementation of a computerized provider order entry system for complex chemotherapy regimens at a large cancer center required intense effort from a multidisciplinary team of clinical and systems experts with experience in all facets of the chemoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4877ea28419be13d17488b9d5c51e3
https://europepmc.org/articles/PMC3140440/
https://europepmc.org/articles/PMC3140440/
Autor:
Nancy T. Sklarin, Mark Markham
Publikováno v:
American Journal of Clinical Oncology. 18:71-73
A case of spontaneous recurrent acute tumor lysis syndrome is presented in a woman with inflammatory breast cancer. The occurrence of tumor lysis syndrome in solid tumors is unusual, and spontaneous cases are rare. This and other unusual aspects of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41be2dba1a77e54abd598f1045bc3009
https://doi.org/10.1097/00000421-199502000-00015
https://doi.org/10.1097/00000421-199502000-00015
Autor:
Corinne B. Winston, Laura Liberman, Jerrold Teitcher, James F. Caravelli, David M. Panicek, Orna Hadar, Nancy T. Sklarin
Publikováno v:
AJR. American journal of roentgenology. 175(3)
We determined the pattern of spread of metastatic lobular carcinoma in the chest, abdomen, and pelvis on CT.We identified 57 women (age range, 30-79 years; mean age, 57 years) with metastatic lobular carcinoma of the breast who underwent CT of the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a89eaa66ae1ababd3b8f7d006217e3
https://pubmed.ncbi.nlm.nih.gov/10954469
https://pubmed.ncbi.nlm.nih.gov/10954469
Autor:
Farrah Mikhail Datko, Gabriella D'Andrea, Maura N. Dickler, Maria Theodoulou, Shari Beth Goldfarb, Diana Lake, Monica Nancy Fornier, Shanu Modi, Nancy T. Sklarin, Elizabeth Anne Comen, Julie Fasano, Devika Gajria, Pamela Drullinsky, Conleth G. Murphy, Angemael Syldor, Sujata Patil, Jennifer Liu, Sarat Chandarlapaty, Clifford Hudis, Chau T. Dang
Publikováno v:
Journal of Clinical Oncology. 30:134-134
134 Background: Pertuzumab (P) is a monoclonal antibody which binds to extracellular domain II of HER2 distally from trastuzumab (H), disrupting HER2 dimerization and signaling. The CLEOPATRA phase III trial showed that HP + docetaxel in HER2+ MBC pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::950bcb3306d4145ac7c84359d1663ad5
https://doi.org/10.1200/jco.2012.30.27_suppl.134
https://doi.org/10.1200/jco.2012.30.27_suppl.134
Publikováno v:
American journal of hematology. 37(2)
The success of allogeneic organ transplantation is in great part due to pharmacologic advances in the area of immunosuppressive therapy. However, this achievement has been attained at the price of an unexpectedly high incidence of malignancies in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab1a4cb6449246d9daad686eb16619d
https://pubmed.ncbi.nlm.nih.gov/1648879
https://pubmed.ncbi.nlm.nih.gov/1648879
Publikováno v:
Clinical Infectious Diseases. 15:738-739
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f11fcb7b4c7d9c38ebc244deca5a5fd
https://doi.org/10.1093/clind/15.4.738
https://doi.org/10.1093/clind/15.4.738