Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Nancy Schultz"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2023)
Depression and anxiety are some of the most prevalent and debilitating mental health conditions in humans. They can present on their own or as co-morbidities with other disorders. Like humans, non-human primates (NHPs) can develop depression- and anx
Externí odkaz:
https://doaj.org/article/71116da2876440a89823fc84071c760b
Autor:
Chelsea M Crooks, Andrea M Weiler, Sierra L Rybarczyk, Mason I Bliss, Anna S Jaeger, Megan E Murphy, Heather A Simmons, Andres Mejia, Michael K Fritsch, Jennifer M Hayes, Jens C Eickhoff, Ann M Mitzey, Elaina Razo, Katarina M Braun, Elizabeth A Brown, Keisuke Yamamoto, Phoenix M Shepherd, Amber Possell, Kara Weaver, Kathleen M Antony, Terry K Morgan, Christina M Newman, Dawn M Dudley, Nancy Schultz-Darken, Eric Peterson, Leah C Katzelnick, Angel Balmaseda, Eva Harris, David H O'Connor, Emma L Mohr, Thaddeus G Golos, Thomas C Friedrich, Matthew T Aliota
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009641 (2021)
Concerns have arisen that pre-existing immunity to dengue virus (DENV) could enhance Zika virus (ZIKV) disease, due to the homology between ZIKV and DENV and the observation of antibody-dependent enhancement (ADE) among DENV serotypes. To date, no st
Externí odkaz:
https://doaj.org/article/1455c754d9084b968c3c722d37483da7
Autor:
Nikki P. L. Toledo, Hongzhao Li, Robert W. Omange, Tamara G. Dacoba, Jose Crecente-Campo, Dane Schalk, Mohammad A. Kashem, Eva Rakasz, Nancy Schultz-Darken, Qingsheng Li, James B. Whitney, Maria J. Alonso, Francis A. Plummer, Ma Luo
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Studies have shown that vaccine vectors and route of immunization can differentially activate different arms of the immune system. However, the effects of different HIV vaccine immunogens on mucosal inflammation have not yet been studied. Because muc
Externí odkaz:
https://doaj.org/article/f5036d8582ec48499d95ddd2513a2d67
Autor:
Dawn M. Dudley, Christina M. Newman, Joseph Lalli, Laurel M. Stewart, Michelle R. Koenig, Andrea M. Weiler, Matthew R. Semler, Gabrielle L. Barry, Katie R. Zarbock, Mariel S. Mohns, Meghan E. Breitbach, Nancy Schultz-Darken, Eric Peterson, Wendy Newton, Emma L. Mohr, Saverio Capuano III, Jorge E. Osorio, Shelby L. O’Connor, David H. O’Connor, Thomas C. Friedrich, Matthew T. Aliota
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Vector saliva can affect infectivity and pathogenesis of vector-borne viruses, but this hasn’t been studied for Zika virus infection. Here, Dudley et al. show that mosquito-mediated Zika infection of macaques results in altered replication kinetics
Externí odkaz:
https://doaj.org/article/31917530d7414bac87d6c4b747a76d29
Autor:
Christina M. Newman, Dawn M. Dudley, Matthew T. Aliota, Andrea M. Weiler, Gabrielle L. Barry, Mariel S. Mohns, Meghan E. Breitbach, Laurel M. Stewart, Connor R. Buechler, Michael E. Graham, Jennifer Post, Nancy Schultz-Darken, Eric Peterson, Wendy Newton, Emma L. Mohr, Saverio Capuano, David H. O’Connor, Thomas C. Friedrich
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Zika virus (ZIKV) is present in body fluids, including saliva, but transmission risk through mucosal contact is not well known. Here, the authors show that oropharyngeal mucosal infection of macaques with a high ZIKV dose results in viremia, but that
Externí odkaz:
https://doaj.org/article/00564ee8a1ce45af98f5098b776f6d85
Autor:
Michelle R Koenig, Elaina Razo, Ann Mitzey, Christina M Newman, Dawn M Dudley, Meghan E Breitbach, Matthew R Semler, Laurel M Stewart, Andrea M Weiler, Sierra Rybarczyk, Kathryn M Bach, Mariel S Mohns, Heather A Simmons, Andres Mejia, Michael Fritsch, Maria Dennis, Leandro B C Teixeira, Michele L Schotzko, T Michael Nork, Carol A Rasmussen, Alex Katz, Veena Nair, Jiancheng Hou, Amy Hartman, James Ver Hoeve, Charlene Kim, Mary L Schneider, Karla Ausderau, Sarah Kohn, Anna S Jaeger, Matthew T Aliota, Jennifer M Hayes, Nancy Schultz-Darken, Jens Eickhoff, Kathleen M Antony, Kevin Noguchi, Xiankun Zeng, Sallie Permar, Vivek Prabhakaran, Saverio Capuano, Thomas C Friedrich, Thaddeus G Golos, David H O'Connor, Emma L Mohr
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0235877 (2020)
Congenital Zika virus (ZIKV) exposure results in a spectrum of disease ranging from severe birth defects to delayed onset neurodevelopmental deficits. ZIKV-related neuropathogenesis, predictors of birth defects, and neurodevelopmental deficits are no
Externí odkaz:
https://doaj.org/article/b8a918ea7e514764bb69f17fe5263421
Autor:
Meghan E Breitbach, Christina M Newman, Dawn M Dudley, Laurel M Stewart, Matthew T Aliota, Michelle R Koenig, Phoenix M Shepherd, Keisuke Yamamoto, Chelsea M Crooks, Ginger Young, Matthew R Semler, Andrea M Weiler, Gabrielle L Barry, Holly Heimsath, Emma L Mohr, Jens Eichkoff, Wendy Newton, Eric Peterson, Nancy Schultz-Darken, Sallie R Permar, Hansi Dean, Saverio Capuano, Jorge E Osorio, Thomas C Friedrich, David H O'Connor
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007766 (2019)
Zika virus (ZIKV) and dengue virus (DENV) are genetically and antigenically related flaviviruses that now co-circulate in much of the tropical and subtropical world. The rapid emergence of ZIKV in the Americas in 2015 and 2016, and its recent associa
Externí odkaz:
https://doaj.org/article/070cb2655c2f4945bf798ac9c466070e
Autor:
Dawn M. Dudley, Matthew T. Aliota, Emma L. Mohr, Andrea M. Weiler, Gabrielle Lehrer-Brey, Kim L. Weisgrau, Mariel S. Mohns, Meghan E. Breitbach, Mustafa N. Rasheed, Christina M. Newman, Dane D. Gellerup, Louise H. Moncla, Jennifer Post, Nancy Schultz-Darken, Michele L. Schotzko, Jennifer M. Hayes, Josh A. Eudailey, M. Anthony Moody, Sallie R. Permar, Shelby L. O’Connor, Eva G. Rakasz, Heather A. Simmons, Saverio Capuano, Thaddeus G. Golos, Jorge E. Osorio, Thomas C. Friedrich, David H. O’Connor
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Animal models of infection with Zika virus (ZIKV) are urgently needed for a better understanding of pathogenesis and for testing potential therapies. Here, the authors describe infection of rhesus macaques with an Asian-lineage ZIKV strain as a relev
Externí odkaz:
https://doaj.org/article/1d500df450f942ebbe6246e44f2a96d7
Autor:
Matthew T Aliota, Dawn M Dudley, Christina M Newman, James Weger-Lucarelli, Laurel M Stewart, Michelle R Koenig, Meghan E Breitbach, Andrea M Weiler, Matthew R Semler, Gabrielle L Barry, Katie R Zarbock, Amelia K Haj, Ryan V Moriarty, Mariel S Mohns, Emma L Mohr, Vanessa Venturi, Nancy Schultz-Darken, Eric Peterson, Wendy Newton, Michele L Schotzko, Heather A Simmons, Andres Mejia, Jennifer M Hayes, Saverio Capuano, Miles P Davenport, Thomas C Friedrich, Gregory D Ebel, Shelby L O'Connor, David H O'Connor
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006964 (2018)
Defining the complex dynamics of Zika virus (ZIKV) infection in pregnancy and during transmission between vertebrate hosts and mosquito vectors is critical for a thorough understanding of viral transmission, pathogenesis, immune evasion, and potentia
Externí odkaz:
https://doaj.org/article/39df6433589043a6a28ef7d6b7c60f56
Autor:
Hongzhao Li, Yan Hai, So-Yon Lim, Nikki Toledo, Jose Crecente-Campo, Dane Schalk, Lin Li, Robert W Omange, Tamara G Dacoba, Lewis R Liu, Mohammad Abul Kashem, Yanmin Wan, Binhua Liang, Qingsheng Li, Eva Rakasz, Nancy Schultz-Darken, Maria J Alonso, Francis A Plummer, James B Whitney, Ma Luo
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202997 (2018)
HIV mutates rapidly and infects CD4+ T cells, especially when they are activated. A vaccine targeting conserved, essential viral elements while limiting CD4+ T cell activation could be effective. Learning from natural immunity observed in a group of
Externí odkaz:
https://doaj.org/article/5a0bd10aa4a94417af351aa2f560411c