Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nancy Santos-Martínez"'
Autor:
Santiago García, Itzel Mercado-Sánchez, Luis Bahena, Yolanda Alcaraz, Marco A. García-Revilla, Juvencio Robles, Nancy Santos-Martínez, David Ordaz-Rosado, Rocío García-Becerra, Miguel A. Vazquez
Publikováno v:
Molecules, Vol 25, Iss 21, p 5134 (2020)
Coumarin-hydroxamic acid derivatives 7a–k were herein designed with a dual purpose: as antiproliferative agents and fluorescent probes. The compounds were synthesized in moderate yields (30–87%) through a simple methodology, biological evaluation
Externí odkaz:
https://doaj.org/article/712fae62cb1b4c7abf8c9b581b80c8ba
Autor:
Stephanie P. Totten, Young Kyuen Im, Eduardo Cepeda Cañedo, Ouafa Najyb, Alice Nguyen, Steven Hébert, Ryuhjin Ahn, Kyle Lewis, Benjamin Lebeau, Rachel La Selva, Valérie Sabourin, Constanza Martínez, Paul Savage, Hellen Kuasne, Daina Avizonis, Nancy Santos Martínez, Catherine Chabot, Adriana Aguilar-Mahecha, Marie-Line Goulet, Matthew Dankner, Michael Witcher, Kevin Petrecca, Mark Basik, Michael Pollak, Ivan Topisirovic, Rongtuan Lin, Peter M. Siegel, Claudia L. Kleinman, Morag Park, Julie St-Pierre, Josie Ursini-Siegel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Complex I inhibition induces oxidative stress leading to cancer cell cytotoxicity. Here, the authors show, in breast cancer models, that inflammatory mediators can potentiate complex I inhibitor phenformin cytotoxicity through STAT1-mediated downregu
Externí odkaz:
https://doaj.org/article/e78e979f7f9a43d280222791ea6273df
Autor:
Steven Hébert, Ryuhjin Ahn, Ivan Topisirovic, Matthew Dankner, Daina Avizonis, Kyle Lewis, Julie St-Pierre, Marie-Line Goulet, Josie Ursini-Siegel, Eduardo Cepeda Cañedo, Mark Basik, Alice Nguyen, Kevin Petrecca, Valerie Sabourin, Nancy Santos Martínez, Constanza Martinez, Benjamin Lebeau, Rongtuan Lin, Morag Park, Ouafa Najyb, Adriana Aguilar-Mahecha, Michael Witcher, Peter M. Siegel, Paul Savage, Catherine Chabot, Rachel La Selva, Young Kyuen Im, Claudia L. Kleinman, Hellen Kuasne, Stephanie Totten, Michael Pollak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications
Nature Communications
Bioenergetic perturbations driving neoplastic growth increase the production of reactive oxygen species (ROS), requiring a compensatory increase in ROS scavengers to limit oxidative stress. Intervention strategies that simultaneously induce energetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efb52addcc93ac7072fb39e5c81282a
https://doaj.org/article/e78e979f7f9a43d280222791ea6273df
https://doaj.org/article/e78e979f7f9a43d280222791ea6273df
Autor:
Nancy, Santos-Martínez, Lorenza, Díaz, Victor M, Ortiz-Ortega, David, Ordaz-Rosado, Heriberto, Prado-Garcia, Euclides, Avila, Fernando, Larrea, Rocío, García-Becerra
Publikováno v:
Am J Cancer Res
Patients with estrogen receptor (ER) α-negative breast tumors have a poor prognosis and are not suitable for hormone therapy. Previously, we demonstrated that calcitriol, the active metabolite of vitamin D, induces ERα expression and re-establishes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34613215cde771b3ac0091a06cdfc336
https://pubmed.ncbi.nlm.nih.gov/35018235
https://pubmed.ncbi.nlm.nih.gov/35018235
Autor:
Itzel Mercado-Sánchez, David Ordaz-Rosado, Clarisa Villegas Gómez, Miguel A. Vázquez, Fernando Hernández-Borja, Marco A. García-Revilla, Yolanda Alcaraz, Rocío García-Becerra, Nancy Santos-Martínez
Publikováno v:
Daru
PURPOSE: Histone deacetylases (HDACs) play a vital role in the epigenetic regulation of gene expression due to their overexpression in several cancer forms. Therefore, these enzymes are considered as a potential anticancer drug target. Different synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a644db3de9ca3051237a52685d42a433
https://europepmc.org/articles/PMC8602590/
https://europepmc.org/articles/PMC8602590/
Autor:
Nancy Santos-Martínez, Luis Bahena, David Ordaz-Rosado, Yolanda Alcaraz, Rocío García-Becerra, Itzel Mercado-Sánchez, Santiago García, Marco A. García-Revilla, Juvencio Robles, Miguel A. Vázquez
Publikováno v:
Molecules
Volume 25
Issue 21
Molecules, Vol 25, Iss 5134, p 5134 (2020)
Volume 25
Issue 21
Molecules, Vol 25, Iss 5134, p 5134 (2020)
Coumarin-hydroxamic acid derivatives 7a&ndash
k were herein designed with a dual purpose: as antiproliferative agents and fluorescent probes. The compounds were synthesized in moderate yields (30&ndash
87%) through a simple methodology, bio
k were herein designed with a dual purpose: as antiproliferative agents and fluorescent probes. The compounds were synthesized in moderate yields (30&ndash
87%) through a simple methodology, bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251ed574148a3731c5e3853e00a78219
http://europepmc.org/articles/PMC7662212
http://europepmc.org/articles/PMC7662212
Autor:
Fernando Larrea, Euclides Avila, Nancy Santos-Martínez, Lorenza Díaz, Janice García-Quiroz, Rocío García-Becerra
Publikováno v:
Journal of Biomedical Science
Background In normal and neoplastic cells, growth-promoting, proangiogenic, cytotoxic and pro-apoptotic effects have all been attributed to cathelicidin antimicrobial peptide (CAMP). Nevertheless, little is known about the factors regulating this pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5b9e39392af28d57b1498fba5eff33
https://doi.org/10.1186/s12929-016-0298-4
https://doi.org/10.1186/s12929-016-0298-4
Autor:
David Ordaz-Rosado, María de Jesús Ibarra-Sánchez, David Barrera, Nancy Santos-Martínez, Galia Lara-Sotelo, José Esparza-López, Fernando Larrea, Andrea Olmos-Ortiz, Euclides Avila, Sofía López, Rocío García-Becerra, Ali Halhali, Lorenza Díaz, Janice García-Quiroz
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 173
Factors affecting vitamin D metabolism may preclude anti-carcinogenic effects of its active metabolite calcitriol. Chronic ethanol consumption is an etiological factor for breast cancer that affects vitamin D metabolism; however, the mechanisms under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c2b982ca204d8bc1b2f5a8cdd3e06e
https://pubmed.ncbi.nlm.nih.gov/27639478
https://pubmed.ncbi.nlm.nih.gov/27639478
Autor:
Rocío García-Becerra, Maŕa J Ibarra-Sánchez, Octavio Villanueva, Nancy Santos-Martínez, Armando Gamboa-Domínguez, David Barrera, David Ordaz-Rosado, Janice García-Quiroz, Euclides Avila, Javier Camacho, Fernando Larrea, José Esparza-López, Ali Halhali, Lorenza Díaz
Publikováno v:
BMC Cancer
Background The oncogenic ether-à-go-go-1 potassium channel (EAG1) activity and expression are necessary for cell cycle progression and tumorigenesis. The active vitamin D metabolite, calcitriol, and astemizole, a promising antineoplastic drug, targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49366b2a53718c4301f83d55314edfe
http://europepmc.org/articles/PMC4194404
http://europepmc.org/articles/PMC4194404
Autor:
José Esparza-López, María de Jesús Ibarra-Sánchez, Fernando Larrea, Javier Camacho, David Barrera, Rocío García-Becerra, Nancy Santos-Martínez, David Ordaz-Rosado, Euclides Avila, Heriberto Medina-Franco, Ali Halhali, Lorenza Díaz, Janice García-Quiroz
Publikováno v:
BMC Cancer
Background Approximately 30% of breast tumors do not express the estrogen receptor (ER) α, which is necessary for endocrine therapy approaches. Studies are ongoing in order to restore ERα expression in ERα-negative breast cancer. The aim of the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d438613348110d829ff300e55a3b3551
https://doi.org/10.1186/1471-2407-14-230
https://doi.org/10.1186/1471-2407-14-230