Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Nancy S Magnuson"'
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002801 (2012)
Externí odkaz:
https://doaj.org/article/b7dc114cadc04823855a4805805ab3e5
Publikováno v:
Acta Agriculturae Slovenica, Vol 108, Iss 2, Pp 65-69 (2017)
Acta agriculturae Slovenica
Acta agriculturae Slovenica
Mitochondrial transcription factor A (TFAM) is a nuclear-encoded mitochondrial protein that plays an important role in energy metabolism and is a candidate gene for fat deposition in cattle and human. In the present study, we characterized the methyl
Autor:
Anya Y. Joyo, Mirko Völkers, Mark A. Sussman, Zeping Wang, Bevan Johnson, Mathias H. Konstandin, Matt Mason, Shabana Din, Peter Erhardt, Nancy S. Magnuson, Christopher T. Cottage, Pearl Quijada
Publikováno v:
Proceedings of the National Academy of Sciences. 110:5969-5974
Mitochondrial morphological dynamics affect the outcome of ischemic heart damage and pathogenesis. Recently, mitochondrial fission protein dynamin-related protein 1 (Drp1) has been identified as a mediator of mitochondrial morphological changes and c
Autor:
Yandong Zhang, Raymond Reeves, Nancy S. Magnuson, Juan Jenny Gu, Zeping Wang, Christine M. Davitt
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 42:1030-1038
Pim-2 kinase is one of the three highly conserved Pim family members which are known to be involved in cell survival and cell proliferation. Here we demonstrate that like Pim-1, Pim-2 also phosphorylates the cell cycle inhibitor p21Cip1/WAF1 (p21) on
Publikováno v:
Animal Genetics. 19:343-348
Summary. Monoclonal antibodies specific for equine T lymphocyte subpopulations were produced and procedures for the continuous culture of equine lymphocytes were developed. These reagents and procedures were used to analyse the appearance, maturation
Autor:
Nancy S. Magnuson, Zhihua Jiang, Jennifer J. Michal, Zeping Wang, David J. Tobey, Michael D. MacNeil
Publikováno v:
International Journal of Biological Sciences
Several reports have shown that urotensin 2 (UTS2) and its receptor (UTS2R) are involved in glucose metabolism and insulin resistance, which lead to development of type 2 diabetes mellitus (T2DM) in humans. In the present study, we annotated both bov
Autor:
Zhihua Jiang, Jennifer J. Michal, David J. Tobey, Zeping Wang, Michael D. MacNeil, Nancy S. Magnuson
Publikováno v:
International Journal of Biological Sciences, Vol 4, Iss 2, Pp 96-102 (2008)
Several reports have shown that urotensin 2 (UTS2) and its receptor (UTS2R) are involved in glucose metabolism and insulin resistance, which lead to development of type 2 diabetes mellitus (T2DM) in humans. In the present study, we annotated both bov
Autor:
Weitao Wu, Steven R. Houser, Sailay Siddiqi, Erik Schaefer, Gregory Emmanuel, Francesca Delucchi, Christopher C. Glembotski, Jenna Fransioli, Piero Anversa, Yu Misao, Mark A. Sussman, Joshua J. Martindale, Annarosa Leri, Kimberlee M. Fischer, Roberto Alvarez, Jan Kajstura, Remus M Beretta, Michael L. Arcarese, John A. Muraski, Grazia Esposito, Natalie Gude, Nancy S. Magnuson, Christopher T. Cottage, Anton Berns, Marcello Rota
Publikováno v:
Nature Medicine. 13:1467-1475
The serine-threonine kinases Pim-1 and Akt regulate cellular proliferation and survival. Although Akt is known to be a crucial signaling protein in the myocardium, the role of Pim-1 has been overlooked. Pim-1 expression in the myocardium of mice decr
Publikováno v:
Molecular Cancer Research. 5:909-922
Previous studies from our laboratory showed that p21Cip1/WAF1 can be phosphorylated by Pim-1 kinase in vitro, implying that part of the function of Pim-1 might involve influencing the cell cycle. In the present study, site-directed mutagenesis and ph