Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nancy S, Krieger"'
Publikováno v:
JBMR Plus, Vol 6, Iss 12, Pp n/a-n/a (2022)
ABSTRACT Metabolic acidosis (MET) stimulates bone resorption through inhibition of osteoblast (OB) bone formation and stimulation of osteoclast (OC) bone resorption. We found that OGR1, a G protein‐coupled proton (H+)‐sensing receptor, was critic
Externí odkaz:
https://doaj.org/article/4ed54782ad9244dc836a9eb5fddb98b9
Autor:
Nancy S Krieger, Luojing Chen, Jennifer Becker, Sean DeBoyace, Hongwei Wang, Murray J Favus, David A Bushinsky
Publikováno v:
JBMR Plus, Vol 4, Iss 4, Pp n/a-n/a (2020)
ABSTRACT To study human idiopathic hypercalciuria (IH), we developed an animal model, genetic hypercalciuric stone‐forming (GHS) rats, whose pathophysiology parallels that in IH. All GHS rats form kidney stones and have decreased BMD and bone quali
Externí odkaz:
https://doaj.org/article/e8bcd703bba94625975e50dafec8f7a6
Autor:
Joshua M, Stern, Robert D, Burk, John, Asplin, Nancy S, Krieger, Sylvia O, Suadicani, Yi, Wang, Mykhaylo, Usyk, Justin A, Lee, Luojing, Chen, Jennifer, Becker, Michaela, Chan, David A, Bushinsky
Publikováno v:
Urolithiasis. 49(3)
Antibiotics can alter the gut microbiome (GMB), which may be associated with stone disease. We sought to determine the effect that antibiotics have on the GMB, urine ion excretion and stone formation in genetic hypercalciuric stone-forming (GHS) rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4314636a56b593cd9babeb987f09fbc9
https://pubmed.ncbi.nlm.nih.gov/33161469
https://pubmed.ncbi.nlm.nih.gov/33161469
Publikováno v:
Journal of Bone and Mineral Research. 3:473-478
Thyroid hormones stimulate bone turnover in vivo and increase Ca release from bone in vitro. To investigate further the effects of thyroid hormones in bone, we have characterized specific nuclear receptors for [125I]tri-iodothyronine (T3) in neonatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb1f67508a1b187bf1ee66ad22aa8c3
https://doi.org/10.1002/jbmr.5650030415
https://doi.org/10.1002/jbmr.5650030415
Publikováno v:
Journal of Bone and Mineral Research. 4:901-909
We have examined the effect of alpha-difluoromethylornithine (DFMO) on bone polyamine content and parathyroid hormone (PTH)- and calcitriol-stimulated bone resorption in cultures of neonatal mouse calvaria. Polyamine content in bone homogenates was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fcdb2cd51f487c7d70006b6405b0cf5
https://doi.org/10.1002/jbmr.5650040615
https://doi.org/10.1002/jbmr.5650040615
Publikováno v:
Kidney International. 55(1):234-243
Alendronate decreases urine calcium and supersaturation in genetic hypercalciuric rats.BackgroundThe mechanism of excess urine calcium excretion in human idiopathic hypercalciuria (IH) has not been determined but may be secondary to enhanced intestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259c2d1d9b6752383e25b19916e3dd73
Autor:
Adeline H, Ng, Kevin K, Frick, Nancy S, Krieger, John R, Asplin, Madison, Cohen-McFarlane, Christopher D, Culbertson, Kelly, Kyker-Snowman, Marc D, Grynpas, David A, Bushinsky
Publikováno v:
Calcified tissue international. 94(5)
Genetic hypercalciuric stone-forming (GHS) rats, bred to maximize urine (u) calcium (Ca) excretion, demonstrate increased intestinal Ca absorption, increased bone Ca resorption, and reduced renal Ca reabsorption, all leading to elevated uCa compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5eaaabeba657ffcfb6d6fbda5e73dfe
https://pubmed.ncbi.nlm.nih.gov/24481706
https://pubmed.ncbi.nlm.nih.gov/24481706
Autor:
Kevin K, Frick, John R, Asplin, Nancy S, Krieger, Christopher D, Culbertson, Daniel M, Asplin, David A, Bushinsky
Publikováno v:
American journal of physiology. Renal physiology. 305(8)
The inbred genetic hypercalciuric stone-forming (GHS) rats exhibit many features of human idiopathic hypercalciuria and have elevated levels of vitamin D receptors (VDR) in calcium (Ca)-transporting organs. On a normal-Ca diet, 1,25(OH)2D3 (1,25D) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1861ab007a2ab841055c190cb7437ae5
https://pubmed.ncbi.nlm.nih.gov/23926184
https://pubmed.ncbi.nlm.nih.gov/23926184
Publikováno v:
Journal of Bone and Mineral Research. 5:159-164
Tumor-associated hypercalcemia is due, in part, to enhanced osteoclastic bone resorption induced by soluble factors elaborated from malignant cells. ras transformation of NIH 3T3 cells results in a 50-fold induction of cathepsin L mRNA and secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f047484da773723b080d04f4adb541d4
https://doi.org/10.1002/jbmr.5650050209
https://doi.org/10.1002/jbmr.5650050209
Publikováno v:
Seminars in dialysis. 16(6)
Metabolic acidosis increases urine calcium excretion without an increase in intestinal calcium absorption, resulting in a net loss of bone mineral. In vitro metabolic acidosis induces bone calcium efflux initially by physicochemical dissolution and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::032dead4611dc7478bcd03377bd4b6a0
https://pubmed.ncbi.nlm.nih.gov/14629607
https://pubmed.ncbi.nlm.nih.gov/14629607