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pro vyhledávání: '"Nancy R. Mack"'
Publikováno v:
Frontiers in Systems Neuroscience, Vol 17 (2023)
Anxiety disorders are the most common class of mental illness in the U.S., affecting 40 million individuals annually. Anxiety is an adaptive response to a stressful or unpredictable life event. Though evolutionarily thought to aid in survival, excess
Externí odkaz:
https://doaj.org/article/740abdd740214e9b87817c478cc41665
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Prefrontal cortical GABAergic interneurons (INs) and their innervations are essential for the execution of complex behaviors such as working memory, social behavior, and fear expression. These behavior regulations are highly dependent on primary long
Externí odkaz:
https://doaj.org/article/178e0aff0d9a45a6a8567fe199b146ed
Autor:
Wen-Jun Gao, Nancy R. Mack
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Abnormal social behavior, including both hypo- and hypersociability, is often observed in neurodevelopmental disorders such as autism spectrum disorders. However, the mechanisms associated with these two distinct social behavior abnormalities remain
Externí odkaz:
https://doaj.org/article/d70fb791c8614d9cb570cf8c41f437ad
The Paraventricular Nucleus of the Thalamus Is an Important Node in the Emotional Processing Network
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
The paraventricular nucleus of the thalamus (PVT) has for decades been acknowledged to be an important node in the limbic system, but studies of emotional processing generally fail to incorporate it into their investigational framework. Here, we prop
Externí odkaz:
https://doaj.org/article/7823b5d5f833430d9ae050e943c72586
Autor:
Linda A. Chamberlin, Sha-Sha Yang, Erin P. McEachern, Joshua T. M. Lucas, Owen W. McLeod II, Claire A. Rolland, Nancy R. Mack, Brielle R. Ferguson, Wen-Jun Gao
Publikováno v:
Neuropsychopharmacology.
Publikováno v:
J Neurosci
Neuronal activity in the prefrontal cortex (PFC) controls dominance hierarchies in groups of animals. Dopamine (DA) strongly modulates PFC activity mainly through D1 receptors (D1Rs) and D2 receptors (D2Rs). Still, it is unclear how these two subpopu
Publikováno v:
Molecular Psychiatry. 27:731-743
The neurobiology of schizophrenia involves multiple facets of pathophysiology, ranging from its genetic basis over changes in neurochemistry and neurophysiology, to the systemic level of neural circuits. Although the precise mechanisms associated wit
Publikováno v:
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
Dysfunction in the prefrontal cortex is commonly implicated in anxiety disorders, but the mechanisms remain unclear. Approach-avoidance conflict tasks have been extensively used in animal research to better understand how changes in neural activity w
Autor:
Wen-Jun Gao, Nancy R. Mack
Publikováno v:
Biological Psychiatry. 89:212-214
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Frontiers in Neural Circuits
Frontiers in Neural Circuits
Prefrontal cortical GABAergic interneurons (INs) and their innervations are essential for the execution of complex behaviors such as working memory, social behavior, and fear expression. These behavior regulations are highly dependent on primary long