Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Nancy R. Forde"'
Autor:
Chapin S. Korosec, Ivan N. Unksov, Pradheebha Surendiran, Roman Lyttleton, Paul M. G. Curmi, Christopher N. Angstmann, Ralf Eichhorn, Heiner Linke, Nancy R. Forde
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Inspired by biology, great progress has been made in creating artificial molecular motors. However, the dream of harnessing proteins – the building blocks selected by nature – to design autonomous motors has so far remained elusive. Here
Externí odkaz:
https://doaj.org/article/320435995bc84d979534476351967116
Autor:
Antonia Kowalewski, Nancy R. Forde
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/40ff58f9bf9b4fc5a5b523bc442ea041
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Multi-step assembly of individual protein building blocks is key to the formation of essential higher-order structures inside and outside of cells. Optical tweezers is a technique well suited to investigate the mechanics and dynamics of these structu
Externí odkaz:
https://doaj.org/article/318e158d9a7444f5b28fe1624b86be8e
Publikováno v:
Physical Review Research, Vol 2, Iss 3, p 033520 (2020)
The mean-squared displacement (MSD) is an averaged quantity widely used to assess anomalous diffusion. In many cases, such as molecular motors with finite processivity, the dynamics of the system of interest produce trajectories of varying duration.
Externí odkaz:
https://doaj.org/article/348ed31cd93848c48e843fe8195532a3
Publikováno v:
Soft Matter. 18:5359-5365
In the past three decades, the technology of optical tweezers has made significant contributions in various scientific areas, including optics, photonics, and nanosciences. Breakthroughs include manipulating particles in both static and dynamic ways,
Publikováno v:
Biophys J
Single-molecule imaging is widely used to determine statistical distributions of molecular properties. One such characteristic is the bending flexibility of biological filaments, which can be parameterized via the persistence length. Quantitative ext
Autor:
Lara S R Small, Martin J Zuckermann, Richard B Sessions, Paul M G Curmi, Heiner Linke, Nancy R Forde, Elizabeth H C Bromley
Publikováno v:
New Journal of Physics, Vol 21, Iss 1, p 013002 (2019)
One challenge to synthetic biology is to design functional machines from natural building blocks, from individual amino acids up to larger motifs such as the coiled coil. Here we investigate a novel bipedal motor concept, the Bar-Hinge Motor (BHM), a
Externí odkaz:
https://doaj.org/article/ed67dbce2f2e42579e01d8972d0d8b50
Autor:
Ivan N. Unksov, Chapin S. Korosec, Pradheebha Surendiran, Damiano Verardo, Roman Lyttleton, Nancy R. Forde, Heiner Linke
Publikováno v:
ACS nanoscience Au. 2(3)
Inspired by molecular motors in biology, there has been significant progress in building artificial molecular motors, using a number of quite distinct approaches. As the constructs become more sophisticated, there is also an increasing need to direct
Autor:
Nancy R. Forde, Aaron Lyons, Sergei P. Boudko, Billy G. Hudson, Alaa Al-Shaer, Yoshihiro Ishikawa
Publikováno v:
Biophys J
Biophysical journal, vol 120, iss 18
Biophysical journal, vol 120, iss 18
Extracellular matrix mechanics influence diverse cellular functions, yet surprisingly little is known about the mechanical properties of their constituent collagen proteins. In particular, network-forming collagen IV, an integral component of basemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add8b3befd845a08ae75098219948afb
https://europepmc.org/articles/PMC8510973/
https://europepmc.org/articles/PMC8510973/
Autor:
Vadim Pedchenko, Alaa Al-Shaer, Billy G. Hudson, Ryan Bauer, Sergei P. Boudko, Elena Pokidysheva, Aaron L. Fidler, Nancy R. Forde
Publikováno v:
The Journal of Biological Chemistry
Collagen IV scaffold is a principal component of the basement membrane (BM), a specialized extracellular matrix that is essential for animal multicellularity and tissue evolution. Scaffold assembly begins with the trimerization of α-chains into prot