Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Nancy Pleshko"'
Publikováno v:
Journal of Structural Biology: X, Vol 10, Iss , Pp 100111- (2024)
Understanding the composition of bone tissue at the submicron level is crucial to elucidate factors contributing to bone disease and fragility. Here, we introduce a novel approach utilizing optical photothermal infrared (O-PTIR) spectroscopy and imag
Externí odkaz:
https://doaj.org/article/784495632d4b49c3818ecd3bf6ae41c3
Autor:
Shital Kandel, William Querido, Jessica M. Falcon, Hannah M. Zlotnick, Ryan C. Locke, Brendan Stoeckl, Jay M. Patel, Chetan A. Patil, Robert L. Mauck, Nancy Pleshko
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Standard assessment of cartilage repair progression by visual arthroscopy can be subjective and may result in suboptimal evaluation. Visible–near infrared (Vis-NIR) fiber optic spectroscopy of joint tissues, including articular cartilage and subcho
Externí odkaz:
https://doaj.org/article/89517e8ac74e45d588bc4e1a93859a6b
Autor:
Minwook Kim, Eiki Koyama, Cheri M. Saunders, William Querido, Nancy Pleshko, Maurizio Pacifici
Publikováno v:
Biology Open, Vol 11, Iss 6 (2022)
The synovial cavity and its fluid are essential for joint function and lubrication, but their developmental biology remains largely obscure. Here, we analyzed E12.5 to E18.5 mouse embryo hindlimbs and discovered that cavitation initiates around E15.0
Externí odkaz:
https://doaj.org/article/5c2382a6f84441d485bfe33f37c932cd
Autor:
Jessica M. Falcon, Shital Kandel, William Querido, Justin Morman, Jay Patel, Liane M. Miller, Robert L. Mauck, Nancy Pleshko
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 2, Iss 1, Pp 100038- (2022)
Introduction: Articular cartilage lacks the capacity for self-repair due to its relative avascularity. Regenerative medicine approaches are now widely investigated, but optimal solutions have not been identified. This is partially attributable to cha
Externí odkaz:
https://doaj.org/article/7e4f5543542d4bbf991e67d5c338505f
Autor:
Abigail L. Hong, Mikayel Ispiryan, Mugdha V. Padalkar, Brandon C. Jones, Alexandra S. Batzdorf, Snehal S. Shetye, Nancy Pleshko, Chamith S. Rajapakse
Publikováno v:
Bone Reports, Vol 11, Iss , Pp - (2019)
The MRI-derived porosity index (PI) is a non-invasively obtained biomarker based on an ultrashort echo time sequence that images both bound and pore water protons in bone, corresponding to water bound to organic collagenous matrix and freely moving w
Externí odkaz:
https://doaj.org/article/1385171a207d4d34b91d9a9c5d6f819a
Autor:
Prapaporn Jongwattanapisan, Masahiko Terajima, Patricia A. Miguez, William Querido, Hideaki Nagaoka, Noriko Sumida, Elizabeth Grace Gurysh, Kristy M. Ainslie, Nancy Pleshko, Lalith Perera, Mitsuo Yamauchi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract We have reported that recombinant biglycan (BGN) core protein accelerates bone formation in vivo by enhancing bone morphogenetic protein (BMP)-2 function. The purpose of the present study was to identify the specific domain (“effector”)
Externí odkaz:
https://doaj.org/article/86b12ac6f51546d392392532a8bb8bf5
Autor:
Karen Wahlstrøm Sanden, Ulrike Böcker, Ragni Ofstad, Mona Elisabeth Pedersen, Vibeke Høst, Nils Kristian Afseth, Sissel Beate Rønning, Nancy Pleshko
Publikováno v:
Foods, Vol 10, Iss 3, p 548 (2021)
Recently, two chicken breast fillet abnormalities, termed Wooden Breast (WB) and Spaghetti Meat (SM), have become a challenge for the chicken meat industry. The two abnormalities share some overlapping morphological features, including myofiber necro
Externí odkaz:
https://doaj.org/article/345cb1c54ca843d686be18e1496c0639
Autor:
Patricia A. Miguez, Stephen A. Tuin, Adam G. Robinson, Joyce Belcher, Prapaporn Jongwattanapisan, Kimberly Perley, Vinicius de Paiva Gonҫalves, Arash Hanifi, Nancy Pleshko, Elisabeth R. Barton
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3223 (2021)
This study evaluated the direct effect of a phytochemical, hesperidin, on pre-osteoblast cell function as well as osteogenesis and collagen matrix quality, as there is little known about hesperidin’s influence in mineralized tissue formation and re
Externí odkaz:
https://doaj.org/article/4583b073466344608598d6e005a9f9fb
Publikováno v:
Molecules, Vol 26, Iss 4, p 922 (2021)
Advances in vibrational spectroscopy have propelled new insights into the molecular composition and structure of biological tissues. In this review, we discuss common modalities and techniques of vibrational spectroscopy, and present key examples to
Externí odkaz:
https://doaj.org/article/90189dd509754efe867dd31a60842ee5
Autor:
Beth G Ashinsky, Kenneth W Fishbein, Erin M Carter, Ping-Chang Lin, Nancy Pleshko, Cathleen L Raggio, Richard G Spencer
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157891 (2016)
The purpose of this study is to evaluate the ability of quantitative magnetic resonance imaging (MRI) to discriminate between skin biopsies from individuals with osteogenesis imperfecta (OI) and skin biopsies from individuals without OI. Skin biopsie
Externí odkaz:
https://doaj.org/article/d12e28910f144e33ac47adc787e169ad