Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Nancy P. Y. Chung"'
Autor:
Nancy P. Y. Chung, K. M. Faisal Khan, Mirko Andreoli, Robert J. Kaner, Sarah L. O’Beirne, Ronald G. Crystal
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract With highly active anti-retroviral therapy (HAART), higher incidence of airway abnormalities is common in the HIV population consistent with the concept of accelerated lung “aging”. Our previous findings demonstrated that HIV induces hum
Externí odkaz:
https://doaj.org/article/f42e5997121649f0abaadddb0a9f8bc9
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Despite the introduction of anti-retroviral therapy, chronic HIV infection is associated with an increased incidence of other comorbidities such as COPD. Based on the knowledge that binding of HIV to human airway basal stem/progenitor cells
Externí odkaz:
https://doaj.org/article/5084a3a5429d4adeaf31eaaa1970d4a3
Autor:
Lingling Wang, Tiao Bu, Xiaolong Wu, Sheng Gao, Xinyao Li, Angela Bryanne De Jesus, Chris K. C. Wong, Hao Chen, Nancy P. Y. Chung, Fei Sun, C. Yan Cheng
Publikováno v:
Cells, Vol 11, Iss 4, p 591 (2022)
Emerging evidence has shown that cell-cell interactions between testicular cells, in particular at the Sertoli cell-cell and Sertoli-germ cell interface, are crucial to support spermatogenesis. The unique ultrastructures that support cell-cell intera
Externí odkaz:
https://doaj.org/article/84b4a70afad84f6aba584b60ddeaba6d
Autor:
Yongxiong Chen, Shiuh-Lin Hwang, Vera S F Chan, Nancy P Y Chung, Shu-Rong Wang, Zhongye Li, Jing Ma, Chia-Wei Lin, Ya-Ju Hsieh, Kao-Ping Chang, Sui-Sum Kung, Yi-Chia Wu, Cheng-Wei Chu, Hsiao-Ting Tai, George F Gao, Bojian Zheng, Kazunari K Yokoyama, Jonathan M Austyn, Chen-Lung S Lin
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003100 (2013)
During disease progression to AIDS, HIV-1 infected individuals become increasingly immunosuppressed and susceptible to opportunistic infections. It has also been demonstrated that multiple subsets of dendritic cells (DC), including DC-SIGN⁺ cells,
Externí odkaz:
https://doaj.org/article/52784e093ab7452998ab0eeb11db4dee
Autor:
Katie Matthews, Nancy P Y Chung, Per Johan Klasse, Magda Moutaftsi, Darrick Carter, André M Salazar, Steven G Reed, Rogier W Sanders, John P Moore
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63785 (2013)
CD14(+) dermal DCs (CD14(+) DDCs) have a natural capacity to activate naïve B-cells. Targeting CD14(+) DDCs is therefore a rational approach for vaccination strategies aimed at improving humoral responses towards poorly immunogenic antigens, for exa
Externí odkaz:
https://doaj.org/article/ffbf75467d35465683639068d5015de6
Autor:
Gözde Isik, Nancy P Y Chung, Thijs van Montfort, Sergey Menis, Katie Matthews, William R Schief, John P Moore, Rogier W Sanders
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67309 (2013)
Broadly neutralizing antibodies (bNAbs) that target the HIV-1 envelope glycoproteins (Env) can prevent virus acquisition, but several Env properties limit its ability to induce an antibody response that is of sufficient quantity and quality. The immu
Externí odkaz:
https://doaj.org/article/7c0462fb0cb547f180f4dedadfc19894
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Despite the introduction of anti-retroviral therapy, chronic HIV infection is associated with an increased incidence of other comorbidities such as COPD. Based on the knowledge that binding of HIV to human airway basal stem/progenitor cells (BC) indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb809171b7abfad343147c3fd57d74d
https://pubmed.ncbi.nlm.nih.gov/33597552
https://pubmed.ncbi.nlm.nih.gov/33597552
Publikováno v:
Journal of immunology (Baltimore, Md., 189(12), 5729-5744. American Association of Immunologists
Targeting CD14(+) dermal-derived dendritic cells (DDCs) is a rational approach for vaccination strategies aimed at improving humoral immune responses, because of their natural ability to stimulate naive B cells. In this study, we show that CD14(+) DD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880db620f3f8c6ffa64b5df0e6a65d8e
https://doi.org/10.4049/jimmunol.1200601
https://doi.org/10.4049/jimmunol.1200601
HIV-1 gp120 Impairs the Induction of B Cell Responses by TLR9-Activated Plasmacytoid Dendritic Cells
Publikováno v:
Journal of immunology (Baltimore, Md., 189(11), 5257-5265. American Association of Immunologists
Plasmacytoid dendritic cells (pDCs) play a central role in innate and adaptive immune responses to viral infections, including HIV type 1 (HIV-1). pDCs produce substantial quantities of type I IFN and proinflammatory cytokines upon stimulation via TL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996ea56814f2e845814c282fe0c56a64
https://doi.org/10.4049/jimmunol.1201905
https://doi.org/10.4049/jimmunol.1201905
Autor:
K.M. Faisal Khan, Nancy P. Y. Chung, Jacqueline Salit, Robert J. Kaner, Xuemei Ou, Ronald G. Crystal
Publikováno v:
Cell Reports, Vol 19, Iss 6, Pp 1091-1100 (2017)
While highly active anti-retroviral therapy has dramatically improved the survival of HIV-infected individuals, there is an increased risk for other co-morbidities, such as COPD, manifesting as emphysema. Given that emphysema originates around the ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e1a3a4569ee007a5cdf71ec51efa1f
https://pubmed.ncbi.nlm.nih.gov/28494859
https://pubmed.ncbi.nlm.nih.gov/28494859