Zobrazeno 1 - 10
of 432
pro vyhledávání: '"Nancy P Keller"'
Autor:
Taylor J Schoen, Dante G Calise, Jin Woo Bok, Morgan A Giese, Chibueze D Nwagwu, Robert Zarnowski, David Andes, Anna Huttenlocher, Nancy P Keller
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011152 (2023)
Hyphal growth is essential for host colonization during Aspergillus infection. The transcription factor ZfpA regulates A. fumigatus hyphal development including branching, septation, and cell wall composition. However, how ZfpA affects fungal growth
Externí odkaz:
https://doaj.org/article/54b4ec096f514a7f8c91391b1326d8c7
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010040 (2022)
Invasive aspergillosis is a common opportunistic infection, causing >50% mortality in infected immunocompromised patients. The specific molecular mechanisms of the innate immune system that prevent pathogenesis of invasive aspergillosis in immunocomp
Externí odkaz:
https://doaj.org/article/f338c178a98c44ae9798109295fc2b4e
Autor:
Jeffrey M Skerker, Kaila M Pianalto, Stephen J Mondo, Kunlong Yang, Adam P Arkin, Nancy P Keller, Igor V Grigoriev, N Louise Louise Glass
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 8 (2021)
Abstract Aspergillus flavusA. flavusA. flavusA. flavus
Externí odkaz:
https://doaj.org/article/eb2eaa81bbf2464fb5b8c8306f835192
Autor:
Nicholas Raffa, Nancy P Keller
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007606 (2019)
Externí odkaz:
https://doaj.org/article/152eb613154642d6a1b0457200792842
Autor:
Emily E Rosowski, Nicholas Raffa, Benjamin P Knox, Netta Golenberg, Nancy P Keller, Anna Huttenlocher
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007229 (2018)
In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease that is often difficult to treat. Exactly how immune mechanisms control A. fumigatus in immunocompetent individuals remains unclear. Here, we use transparent zebra
Externí odkaz:
https://doaj.org/article/191f39c3f6d840f980c2ebbe4eeb9bd7
Autor:
Abigail L Lind, Jennifer H Wisecaver, Catarina Lameiras, Philipp Wiemann, Jonathan M Palmer, Nancy P Keller, Fernando Rodrigues, Gustavo H Goldman, Antonis Rokas
Publikováno v:
PLoS Biology, Vol 15, Iss 11, p e2003583 (2017)
Filamentous fungi produce a diverse array of secondary metabolites (SMs) critical for defense, virulence, and communication. The metabolic pathways that produce SMs are found in contiguous gene clusters in fungal genomes, an atypical arrangement for
Externí odkaz:
https://doaj.org/article/8e72f4a479e1493e8bd14b9f1e115eef
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006424 (2017)
Externí odkaz:
https://doaj.org/article/6db9cbab9b784e9f9d87ca960da69cb4
Autor:
Erwin Berthier, Fang Yun Lim, Qing Deng, Chun-Jun Guo, Dimitrios P Kontoyiannis, Clay C C Wang, Julie Rindy, David J Beebe, Anna Huttenlocher, Nancy P Keller
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003289 (2013)
The secondary metabolome provides pathogenic fungi with a plethoric and versatile panel of molecules that can be deployed during host ingress. While powerful genetic and analytical chemistry methods have been developed to identify fungal secondary me
Externí odkaz:
https://doaj.org/article/8ae9616b3bbb4715a47a40d4e4c2844a
Autor:
Jonathan M Palmer, Jeffrey M Theisen, Rocio M Duran, W Scott Grayburn, Ana M Calvo, Nancy P Keller
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003193 (2013)
Secondary metabolism and development are linked in Aspergillus through the conserved regulatory velvet complex composed of VeA, VelB, and LaeA. The founding member of the velvet complex, VeA, shuttles between the cytoplasm and nucleus in response to
Externí odkaz:
https://doaj.org/article/9a8f5a82460f443eacbcc009d8100595
Autor:
Relebohile Sekonyela, Jonathan M Palmer, Jin-Woo Bok, Sachin Jain, Erwin Berthier, Ry Forseth, Frank Schroeder, Nancy P Keller
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62591 (2013)
Dimeric basic leucine zipper (bZIP) proteins are conserved transcriptional enhancers found in all eukaryotes. A recently reported and novel function for bZIPs is association of these proteins with secondary metabolite production in filamentous fungi.
Externí odkaz:
https://doaj.org/article/392a2e729f6641d5b97ed222fcbd96ad