Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Nancy M. Sherwood"'
Autor:
Ellen R Busby, Nancy M Sherwood
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174452 (2017)
Gonadotropin-releasing hormone (GnRH) is important in the control of reproduction, but its actions in non-reproductive processes are less well known. In this study we examined the effect of disrupting the GnRH receptor in mice to determine if growth,
Externí odkaz:
https://doaj.org/article/157c2012927e4111abde406db7c9f17f
Autor:
Jenny Clarkson, Günther Schütz, Nancy M. Sherwood, Ellen R. Busby, Allan E. Herbison, Milen Kirilov
Publikováno v:
The Journal of Neuroscience. 34:15297-15305
Sex differences in brain function underlie robust differences between males and females in both normal and disease states. Although alternative mechanisms exist, sexual differentiation of the male mammalian brain is initiated predominantly by testost
Autor:
Graeme J. Roch, Nancy M. Sherwood
Publikováno v:
Genome Biology and Evolution
The cystine knot growth factor (CKGF) superfamily includes important secreted developmental regulators, including the families of transforming growth factor beta, nerve growth factor, platelet-derived growth factor, and the glycoprotein hormones (GPH
Publikováno v:
Molecular Biology and Evolution
This work was supported by a grant from the Canadian Natural Sciences and Engineering Council (NSERC). Gonadotropin-releasing hormone (GnRH) is a critical reproductive regulator in vertebrates. Homologous peptides are also found in invertebrates, wit
Autor:
Nancy M. Sherwood, Ellen R. Busby
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174452 (2017)
PLoS ONE
PLoS ONE
Gonadotropin-releasing hormone (GnRH) is important in the control of reproduction, but its actions in non-reproductive processes are less well known. In this study we examined the effect of disrupting the GnRH receptor in mice to determine if growth,
Autor:
Graeme J. Roch, Nancy M. Sherwood
Publikováno v:
Integrative and Comparative Biology. 50:86-97
Stanniocalcin (STC) is present throughout vertebrates, including humans, but a structure for STC has not been identified in animals that evolved before bony fish. The origin of this pleiotropic hormone known to regulate calcium is not clear. In the p
Publikováno v:
General and Comparative Endocrinology. 161:3-12
Modern fish are the result of major changes in evolution including three possible duplications of the whole genome. Retained duplicate genes are often involved with metabolism, transcription, neurogenic processes and development. Here we examine the
Publikováno v:
Journal of Molecular Endocrinology. 41:343-366
A group of ten hormones in humans are structurally related and known as the secretin superfamily. These hormones bind to G-protein-coupled receptors that activate the cAMP pathway and are clustered as the secretin or B family. We used an evolutionary
Autor:
Nancy M. Sherwood, Emma R. Isaac
Publikováno v:
Molecular and Cellular Endocrinology. 280:13-19
Mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP) show high mortality during the postnatal period, as well as impaired reproduction in females. This study characterizes the reproductive phenotype in female mice lacking PACAP due
Autor:
Antonio Vidal-Puig, Emma R. Isaac, Bruce A. Adams, Nancy M. Sherwood, Sarah L. Gray, Antonio C. Bianco
Publikováno v:
Endocrinology. 149:1571-1580
Disruption of the pituitary adenylate cyclase-activating polypeptide (PACAP) gene in mice has demonstrated a role for this highly conserved neuropeptide in the regulation of metabolism and temperature control. Localization of PACAP neurons within hyp